Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner
Cano-Rodriguez, David, Gjaltema, Rutger A F, Jilderda, Laura J, Jellema, Pytrick, Dokter-Fokkens, Jelleke, Ruiters, Marcel H J, Rots, Marianne G
Published in Nature communications (10.08.2016)
Published in Nature communications (10.08.2016)
Get full text
Journal Article
Targeting Rapamycin to Podocytes Using a Vascular Cell Adhesion Molecule-1 (VCAM-1)-Harnessed SAINT-Based Lipid Carrier System
Visweswaran, Ganesh Ram R, Gholizadeh, Shima, Ruiters, Marcel H J, Molema, Grietje, Kok, Robbert J, Kamps, Jan A A M
Published in PloS one (25.09.2015)
Published in PloS one (25.09.2015)
Get full text
Journal Article
Endothelium-targeted delivery of dexamethasone by anti-VCAM-1 SAINT-O-Somes in mouse endotoxemia
Li, Ranran, Kowalski, Piotr S, Morselt, Henriëtte W M, Schepel, Ilona, Jongman, Rianne M, Aslan, Adnan, Ruiters, Marcel H J, Zijlstra, Jan G, Molema, Grietje, van Meurs, Matijs, Kamps, Jan A A M
Published in PloS one (15.05.2018)
Published in PloS one (15.05.2018)
Get full text
Journal Article
Experimental mitochondria-targeted DNA methylation identifies GpC methylation, not CpG methylation, as potential regulator of mitochondrial gene expression
van der Wijst, Monique G P, van Tilburg, Amanda Y, Ruiters, Marcel H J, Rots, Marianne G
Published in Scientific reports (14.03.2017)
Published in Scientific reports (14.03.2017)
Get full text
Journal Article
Cationic lipid-formulated DNA vaccine against hepatitis B virus: immunogenicity of MIDGE-Th1 vectors encoding small and large surface antigen in comparison to a licensed protein vaccine
Endmann, Anne, Klünder, Katharina, Kapp, Kerstin, Riede, Oliver, Oswald, Detlef, Talman, Eduard G, Schroff, Matthias, Kleuss, Christiane, Ruiters, Marcel H J, Juhls, Christiane
Published in PloS one (03.07.2014)
Published in PloS one (03.07.2014)
Get full text
Journal Article
Efficient nontoxic delivery of PD-L1 and PD-L2 siRNA into dendritic cell vaccines using the cationic lipid SAINT-18
Roeven, Mieke W H, Hobo, Willemijn, van der Voort, Robbert, Fredrix, Hanny, Norde, Wieger J, Teijgeler, Kasper, Ruiters, Marcel H J, Schaap, Nicolaas, Dolstra, Harry
Published in Journal of immunotherapy (1997) (01.05.2015)
Published in Journal of immunotherapy (1997) (01.05.2015)
Get more information
Journal Article
The Mitochondrial Epigenome: An Unexplored Avenue to Explain Unexplained Myopathies?
Mposhi, Archibold, Liang, Lin, Mennega, Kevin P, Yildiz, Dilemin, Kampert, Crista, Hof, Ingrid H, Jellema, Pytrick G, de Koning, Tom J, Faber, Klaas Nico, Ruiters, Marcel H J, Niezen-Koning, Klary E, Rots, Marianne G
Published in International journal of molecular sciences (16.02.2022)
Published in International journal of molecular sciences (16.02.2022)
Get full text
Journal Article
Combination of MIDGE-Th1 DNA vaccines with the cationic lipid SAINT-18: Studies on formulation, biodistribution and vector clearance
Endmann, Anne, Oswald, Detlef, Riede, Oliver, Talman, Eduard G, Vos, Roelien E, Schroff, Matthias, Kleuss, Christiane, Ruiters, Marcel H.J, Juhls, Christiane
Published in Vaccine (05.06.2014)
Published in Vaccine (05.06.2014)
Get full text
Journal Article
Anti-VCAM‑1 and Anti-E-selectin SAINT-O-Somes for Selective Delivery of siRNA into Inflammation-Activated Primary Endothelial Cells
Kowalski, Piotr S, Lintermans, Lucas L, Morselt, Henriëtte W. M, Leus, Niek G. J, Ruiters, Marcel H. J, Molema, Grietje, Kamps, Jan A. A. M
Published in Molecular pharmaceutics (05.08.2013)
Published in Molecular pharmaceutics (05.08.2013)
Get full text
Journal Article
Effective siRNA delivery to inflamed primary vascular endothelial cells by anti-E-selectin and anti-VCAM-1 PEGylated SAINT-based lipoplexes
Leus, Niek G.J., Talman, Eduard G., Ramana, Pranov, Kowalski, Piotr S., Woudenberg-Vrenken, Titia E., Ruiters, Marcel H.J., Molema, Grietje, Kamps, Jan A.A.M.
Published in International journal of pharmaceutics (01.01.2014)
Published in International journal of pharmaceutics (01.01.2014)
Get full text
Journal Article
VCAM-1 specific PEGylated SAINT-based lipoplexes deliver siRNA to activated endothelium in vivo but do not attenuate target gene expression
Leus, Niek G.J., Morselt, Henriëtte W.M., Zwiers, Peter J., Kowalski, Piotr S., Ruiters, Marcel H.J., Molema, Grietje, Kamps, Jan A.A.M.
Published in International journal of pharmaceutics (20.07.2014)
Published in International journal of pharmaceutics (20.07.2014)
Get full text
Journal Article
Targeted transfection increases siRNA uptake and gene silencing of primary endothelial cells in vitro — A quantitative study
Ásgeirsdóttir, Sigridur A., Talman, Eduard G., de Graaf, Inge A., Kamps, Jan A.A.M., Satchell, Simon C., Mathieson, Peter W., Ruiters, Marcel H.J., Molema, Grietje
Published in Journal of controlled release (25.01.2010)
Published in Journal of controlled release (25.01.2010)
Get full text
Journal Article
Establishment of protein delivery systems targeting podocytes
Chiang, Wen Chih, Geel, Tessa M, Altintas, Mehmet M, Sever, Sanja, Ruiters, Marcel H J, Reiser, Jochen
Published in PloS one (29.07.2010)
Published in PloS one (29.07.2010)
Get full text
Journal Article
Targeted SAINT-O-Somes for improved intracellular delivery of siRNA and cytotoxic drugs into endothelial cells
Adrian, Joanna E., Morselt, Henriëtte W.M., Süss, Regine, Barnert, Sabine, Kok, Jan Willem, Ásgeirsdóttir, Sigridur A., Ruiters, Marcel H.J., Molema, Grietje, Kamps, Jan A.A.M.
Published in Journal of controlled release (15.06.2010)
Published in Journal of controlled release (15.06.2010)
Get full text
Journal Article
TCTN2: a novel tumor marker with oncogenic properties
Cano-Rodriguez, David, Campagnoli, Susanna, Grandi, Alberto, Parri, Matteo, Camilli, Elisa De, Song, Chaojun, Jin, Boquan, Lacombe, Aurelien, Pierleoni, Andrea, Bombaci, Mauro, Cordiglieri, Chiara, Ruiters, Marcel Hj, Viale, Giuseppe, Terracciano, Luigi, Sarmientos, Paolo, Abrignani, Sergio, Grandi, Guido, Pileri, Piero, Rots, Marianne G, Grifantini, Renata
Published in Oncotarget (10.11.2017)
Published in Oncotarget (10.11.2017)
Get full text
Journal Article
SAINT-liposome-polycation particles, a new carrier for improved delivery of siRNAs to inflamed endothelial cells
Kowalski, Piotr S., Kuninty, Praneeth R., Bijlsma, Klaas T., Stuart, Marc C.A., Leus, Niek G.J., Ruiters, Marcel H.J., Molema, Grietje, Kamps, Jan A.A.M.
Published in European journal of pharmaceutics and biopharmaceutics (01.01.2015)
Published in European journal of pharmaceutics and biopharmaceutics (01.01.2015)
Get full text
Journal Article
Targeted DNA Methylation by a DNA Methyltransferase Coupled to a Triple Helix Forming Oligonucleotide To Down-Regulate the Epithelial Cell Adhesion Molecule
van der Gun, Bernardina T. F, Maluszynska-Hoffman, Maria, Kiss, Antal, Arendzen, Alice J, Ruiters, Marcel H. J, McLaughlin, Pamela M. J, Weinhold, Elmar, Rots, Marianne G
Published in Bioconjugate chemistry (21.07.2010)
Published in Bioconjugate chemistry (21.07.2010)
Get full text
Journal Article
Serum insensitive, intranuclear protein delivery by the multipurpose cationic lipid SAINT-2
VAN DER GUN, Bernardina T. F, MONAMI, Amélie, MCLAUGHLIN, Pamela M. J, LAARMANN, Sven, RASKO, Tamas, SLASKA-KISS, Krystyna, WEINHOLD, Elmar, WASSERKORT, Reinhold, DE LEIJ, Lou F. M. H, RUITERS, Marcel H. J, KISS, Antal
Published in Journal of controlled release (20.11.2007)
Published in Journal of controlled release (20.11.2007)
Get full text
Journal Article