Generation, Characterization, and Quantitative Bioanalysis of Drug/Anti-drug Antibody Immune Complexes to Facilitate Dedicated In Vivo Studies
Hoffmann, Eugenia, Jordan, Gregor, Lauer, Matthias, Ringler, Philippe, Kusznir, Eric A., Rufer, Arne C., Huber, Sylwia, Jochner, Anton, Winter, Gerhard, Staack, Roland F.
Published in Pharmaceutical research (01.09.2019)
Published in Pharmaceutical research (01.09.2019)
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Journal Article
Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance
Bocquet, Nicolas, Kohler, Josiane, Hug, Melanie N., Kusznir, Eric A., Rufer, Arne C., Dawson, Roger J., Hennig, Michael, Ruf, Armin, Huber, Walter, Huber, Sylwia
Published in Biochimica et biophysica acta (01.05.2015)
Published in Biochimica et biophysica acta (01.05.2015)
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Journal Article
Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors
Scott-Dennis, Morgan, Rafani, Fikri A., Yi, Yicheng, Perera, Themiya, Harwood, Clare R., Guba, Wolfgang, Rufer, Arne C., Grether, Uwe, Veprintsev, Dmitry B., Sykes, David A.
Published in Frontiers in pharmacology (11.08.2023)
Published in Frontiers in pharmacology (11.08.2023)
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Journal Article
Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody
Favuzza, Paola, Guffart, Elena, Tamborrini, Marco, Scherer, Bianca, Dreyer, Anita M, Rufer, Arne C, Erny, Johannes, Hoernschemeyer, Joerg, Thoma, Ralf, Schmid, Georg, Gsell, Bernard, Lamelas, Araceli, Benz, Joerg, Joseph, Catherine, Matile, Hugues, Pluschke, Gerd, Rudolph, Markus G
Published in eLife (14.02.2017)
Published in eLife (14.02.2017)
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Journal Article
Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs
Plath, Friederike, Ringler, Philippe, Graff-Meyer, Alexandra, Stahlberg, Henning, Lauer, Matthias E, Rufer, Arne C, Graewert, Melissa A, Svergun, Dmitri, Gellermann, Gerald, Finkler, Christof, Stracke, Jan O, Koulov, Atanas, Schnaible, Volker
Published in mAbs (03.07.2016)
Published in mAbs (03.07.2016)
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Journal Article
Structure and Function of Purified Monoclonal Antibody Dimers Induced by Different Stress Conditions
Paul, Rajsekhar, Graff-Meyer, Alexandra, Stahlberg, Henning, Lauer, Matthias E., Rufer, Arne C., Beck, Hermann, Briguet, Alexandre, Schnaible, Volker, Buckel, Thomas, Boeckle, Sabine
Published in Pharmaceutical research (01.08.2012)
Published in Pharmaceutical research (01.08.2012)
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Journal Article
The Crystal Structure of Carnitine Palmitoyltransferase 2 and Implications for Diabetes Treatment
Rufer, Arne C., Thoma, Ralf, Benz, Jörg, Stihle, Martine, Gsell, Bernard, De Roo, Elodie, Banner, David W., Mueller, Francis, Chomienne, Odile, Hennig, Michael
Published in Structure (London) (01.04.2006)
Published in Structure (London) (01.04.2006)
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Journal Article
Novel β‐Glucocerebrosidase Activators That Bind to a New Pocket at a Dimer Interface and Induce Dimerization
Benz, Joerg, Rufer, Arne C., Huber, Sylwia, Ehler, Andreas, Hug, Melanie, Topp, Andreas, Guba, Wolfgang, Hofmann, Eva Carolina, Jagasia, Ravi, Rodríguez Sarmiento, Rosa María
Published in Angewandte Chemie International Edition (01.03.2021)
Published in Angewandte Chemie International Edition (01.03.2021)
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Journal Article
Structural insight into function and regulation of carnitine palmitoyltransferase
Rufer, Arne C, Thoma, Ralf, Hennig, Michael
Published in Cellular and molecular life sciences : CMLS (01.08.2009)
Published in Cellular and molecular life sciences : CMLS (01.08.2009)
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Journal Article
Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain
Richter, Kirsten, Rufer, Arne C., Muller, Magali, Burger, Dominique, Casagrande, Fabio, Grossenbacher, Tabea, Huber, Sylwia, Hug, Melanie N., Koldewey, Philipp, D'Osualdo, Andrea, Schlatter, Daniel, Stoll, Theodor, Rudolph, Markus G.
Published in The Journal of biological chemistry (05.06.2020)
Published in The Journal of biological chemistry (05.06.2020)
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Evaluation of Tetrazine Tracers for Pretargeted Imaging within the Central Nervous System
Edelmann, Martin R., Bredack, Christoph, Belli, Sara, Mohr, Peter, Imhoff, Marie-Paule, Reggiani, Flore, Kusznir, Eric A., Rufer, Arne C., Holt, Daniel P., Valentine, Heather, Wong, Dean F., Dannals, Robert F., Honer, Michael, Gobbi, Luca C.
Published in Bioconjugate chemistry (18.10.2023)
Published in Bioconjugate chemistry (18.10.2023)
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Journal Article
Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells
Sarott, Roman C, Westphal, Matthias V, Pfaff, Patrick, Korn, Claudia, Sykes, David A, Gazzi, Thais, Brennecke, Benjamin, Atz, Kenneth, Weise, Marie, Mostinski, Yelena, Hompluem, Pattarin, Koers, Eline, Miljuš, Tamara, Roth, Nicolas J, Asmelash, Hermon, Vong, Man C, Piovesan, Jacopo, Guba, Wolfgang, Rufer, Arne C, Kusznir, Eric A, Huber, Sylwia, Raposo, Catarina, Zirwes, Elisabeth A, Osterwald, Anja, Pavlovic, Anto, Moes, Svenja, Beck, Jennifer, Benito-Cuesta, Irene, Grande, Teresa, Ruiz de Martı́n Esteban, Samuel, Yeliseev, Alexei, Drawnel, Faye, Widmer, Gabriella, Holzer, Daniela, van der Wel, Tom, Mandhair, Harpreet, Yuan, Cheng-Yin, Drobyski, William R, Saroz, Yurii, Grimsey, Natasha, Honer, Michael, Fingerle, Jürgen, Gawrisch, Klaus, Romero, Julian, Hillard, Cecilia J, Varga, Zoltan V, van der Stelt, Mario, Pacher, Pal, Gertsch, Jürg, McCormick, Peter J, Ullmer, Christoph, Oddi, Sergio, Maccarrone, Mauro, Veprintsev, Dmitry B, Nazaré, Marc, Grether, Uwe, Carreira, Erick M
Published in Journal of the American Chemical Society (07.10.2020)
Published in Journal of the American Chemical Society (07.10.2020)
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Journal Article
EFMC: Trends in Medicinal Chemistry and Chemical Biology
Auberson, Yves P., Arimondo, Paola B., Duca, Maria, Essig, Sebastian, Grether, Uwe, Rufer, Arne C., Sbardella, Gianluca, Schopfer, Ulrich, Torrens, Antoni, Stelt, Mario, Vauzeilles, Boris, Vázquez, Olalla, Zhang, Andrew X.
Published in Chembiochem : a European journal of chemical biology (03.04.2023)
Published in Chembiochem : a European journal of chemical biology (03.04.2023)
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Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe
Gazzi, Thais, Brennecke, Benjamin, Atz, Kenneth, Korn, Claudia, Sykes, David, Forn-Cuni, Gabriel, Pfaff, Patrick, Sarott, Roman C, Westphal, Matthias V, Mostinski, Yelena, Mach, Leonard, Wasinska-Kalwa, Malgorzata, Weise, Marie, Hoare, Bradley L, Milju, Tamara, Mexi, Maira, Roth, Nicolas, Koers, Eline J, Guba, Wolfgang, Alker, Andr, Rufer, Arne C, Kusznir, Eric A, Huber, Sylwia, Raposo, Catarina, Zirwes, Elisabeth A, Osterwald, Anja, Pavlovic, Anto, Moes, Svenja, Beck, Jennifer, Nettekoven, Matthias, Benito-Cuesta, Irene, Grande, Teresa, Drawnel, Faye, Widmer, Gabriella, Holzer, Daniela, van der Wel, Tom, Mandhair, Harpreet, Honer, Michael, Fingerle, Jürgen, Scheffel, Jörg, Broichhagen, Johannes, Gawrisch, Klaus, Romero, Julián, Hillard, Cecilia J, Varga, Zoltan V, van der Stelt, Mario, Pacher, Pal, Gertsch, Jürg, Ullmer, Christoph, McCormick, Peter J, Oddi, Sergio, Spaink, Herman P, Maccarrone, Mauro, Veprintsev, Dmitry B, Carreira, Erick M, Grether, Uwe, Nazaré, Marc
Published in Chemical science (Cambridge) (18.05.2022)
Published in Chemical science (Cambridge) (18.05.2022)
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Journal Article
Reply to Alarcon and Borroto: Small molecule AX-024 reduces T cell proliferation independently of CD3ε-Nck1 interaction at SH3.1
Richter, Kirsten, Rufer, Arne C., Muller, Magali, Burger, Dominique, Casagrande, Fabio, Grossenbacher, Tabea, Huber, Sylwia, Hug, Melanie N., Koldewey, Philipp, D'Osualdo, Andrea, Schlatter, Daniel, Stoll, Theodor, Rudolph, Markus G.
Published in The Journal of biological chemistry (17.07.2020)
Published in The Journal of biological chemistry (17.07.2020)
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Journal Article
Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP
Lauer, Matthias E., Graff-Meyer, Alexandra, Rufer, Arne C., Maugeais, Cyrille, von der Mark, Elisabeth, Matile, Hugues, D’Arcy, Brigitte, Magg, Christine, Ringler, Philippe, Müller, Shirley A., Scherer, Sebastian, Dernick, Gregor, Thoma, Ralf, Hennig, Michael, Niesor, Eric J., Stahlberg, Henning
Published in Journal of structural biology (01.05.2016)
Published in Journal of structural biology (01.05.2016)
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Journal Article
Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects
Aebi, Johannes, Atz, Kenneth, Ametamey, Simon M, Benz, Jörg, Blaising, Julie, Butini, Stefania, Campiani, Giuseppe, Carreira, Erick M, Collin, Ludovic, De Lago, Eva, Gazzi, Thais, Gertsch, Jürg, Gobbi, Luca, Guba, Wolfgang, Fernández-Ruiz, Javier, Fingerle, Jürgen, Haider, Ahmed, He, Yingfang, Heitman, Laura H, Honer, Michael, Hunziker, Daniel, Kuhn, Bernd, Maccarrone, Mauro, Märki, Hans Peter, Martin, Rainer E, Mohr, Peter, Mu, Linjing, Nazaré, Marc, Nippa, David F, Oddi, Sergio, O'Hara, Fionn, Pacher, Pal, Romero, Julian, Röver, Stephan, Rufer, Arne C, Schibli, Roger, Schneider, Gisbert, Stepan, Antonia F, Sykes, David A, Ullmer, Christoph, Van der Stelt, Mario, Veprintsev, Dmitry B, Wittwer, Matthias B, Grether, Uwe
Published in Chimia (21.08.2024)
Published in Chimia (21.08.2024)
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Journal Article
A Novel Selective Inverse Agonist of the CB 2 Receptor as a Radiolabeled Tool Compound for Kinetic Binding Studies
Martella, Andrea, Sijben, Huub, Rufer, Arne C, Grether, Uwe, Fingerle, Juergen, Ullmer, Christoph, Hartung, Thomas, IJzerman, Adriaan P, van der Stelt, Mario, Heitman, Laura H
Published in Molecular pharmacology (01.10.2017)
Published in Molecular pharmacology (01.10.2017)
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Journal Article
Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies
Burger, Dominique, Stihle, Martine, Sharma, Ashwani, Di Lello, Paola, Benz, Jörg, D'Arcy, Brigitte, Debulpaep, Maja, Fry, David, Huber, Walter, Kremer, Thomas, Laeremans, Toon, Matile, Hugues, Ross, Alfred, Rufer, Arne C., Schoch, Guillaume, Steinmetz, Michel O., Steyaert, Jan, Rudolph, Markus G., Thoma, Ralf, Ruf, Armin
Published in The Journal of biological chemistry (29.07.2016)
Published in The Journal of biological chemistry (29.07.2016)
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