SFRP1 modulates astrocyte-to-microglia crosstalk in acute and chronic neuroinflammation
Rueda-Carrasco, Javier, Martin-Bermejo, María Jesús, Pereyra, Guadalupe, Mateo, María Inés, Borroto, Aldo, Brosseron, Frederic, Kummer, Markus P, Schwartz, Stephanie, López-Atalaya, José P, Alarcon, Balbino, Esteve, Pilar, Heneka, Michael T, Bovolenta, Paola
Published in EMBO reports (04.11.2021)
Published in EMBO reports (04.11.2021)
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Journal Article
Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models
Rueda-Carrasco, Javier, Sokolova, Dimitra, Lee, Sang-Eun, Childs, Thomas, Jurčáková, Natália, Crowley, Gerard, De Schepper, Sebastiaan, Ge, Judy Z, Lachica, Joanne I, Toomey, Christina E, Freeman, Oliver J, Hardy, John, Barnes, Samuel J, Lashley, Tammaryn, Stevens, Beth, Chang, Sunghoe, Hong, Soyon
Published in The EMBO journal (04.10.2023)
Published in The EMBO journal (04.10.2023)
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Journal Article
Perivascular cells induce microglial phagocytic states andsynaptic engulfment via SPP1 in mouse models of Alzheimer’sdisease
De Schepper, Sebastiaan, Ge, Judy Z, Crowley, Gerard, Ferreira, Laís S. S, Garceau, Dylan, Toomey, Christina E, Sokolova, Dimitra, Rueda-Carrasco, Javier, Shin, Sun-Hye, Kim, Jung-Seok, Childs, Thomas, Lashley, Tammaryn, Burden, Jemima J, Sasner, Michael, Sala Frigerio, Carlo, Jung, Steffen, Hong, Soyon
Published in Nature neuroscience (01.03.2023)
Published in Nature neuroscience (01.03.2023)
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Journal Article
Sfrp1 deficiency makes retinal photoreceptors prone to degeneration
Cisneros, Elsa, di Marco, Fabiana, Rueda-Carrasco, Javier, Lillo, Concepción, Pereyra, Guadalupe, Martín-Bermejo, María Jesús, Vargas, Alba, Sanchez, Rocío, Sandonís, África, Esteve, Pilar, Bovolenta, Paola
Published in Scientific reports (20.03.2020)
Published in Scientific reports (20.03.2020)
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Journal Article
Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease
De Schepper, Sebastiaan, Ge, Judy Z., Crowley, Gerard, Ferreira, Laís S. S., Garceau, Dylan, Toomey, Christina E., Sokolova, Dimitra, Rueda-Carrasco, Javier, Shin, Sun-Hye, Kim, Jung-Seok, Childs, Thomas, Lashley, Tammaryn, Burden, Jemima J., Sasner, Michael, Sala Frigerio, Carlo, Jung, Steffen, Hong, Soyon
Published in Nature neuroscience (01.03.2023)
Published in Nature neuroscience (01.03.2023)
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Journal Article
Microglia Detect Externalized Phosphatidylserine on Synapses for Elimination via TREM2 in Alzheimer's Disease Models
Rueda-Carrasco, Javier, Sokolova, Dimitra, Sang-Eun, Lee, Childs, Thomas, Jurcakova, Natalia, De Schepper, Sebastiaan, Ge, Judy Z, Lachica, Joanne I, Toomey, Christina E, Freeman, Oliver J, Hardy, John, Stevens, Beth, Lashley, Tammaryn, Chang, Sunghoe, Hong, Soyon
Published in bioRxiv (05.04.2022)
Published in bioRxiv (05.04.2022)
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Paper
Elevated levels of Secreted-Frizzled-Related-Protein 1 contribute to Alzheimer’s disease pathogenesis
Esteve, Pilar, Rueda-Carrasco, Javier, Inés Mateo, María, Martin-Bermejo, María Jesús, Draffin, Jonathan, Pereyra, Guadalupe, Sandonís, África, Crespo, Inmaculada, Moreno, Inmaculada, Aso, Ester, Garcia-Esparcia, Paula, Gomez-Tortosa, Estrella, Rábano, Alberto, Fortea, Juan, Alcolea, Daniel, Lleo, Alberto, Heneka, Michael T., Valpuesta, José M., Esteban, José A., Ferrer, Isidro, Domínguez, Mercedes, Bovolenta, Paola
Published in Nature neuroscience (01.08.2019)
Published in Nature neuroscience (01.08.2019)
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Journal Article
Author Correction: Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer’s disease models
Rueda-Carrasco, Javier, Sokolova, Dimitra, Lee, Sang-Eun, Childs, Thomas, Jurčáková, Natália, Crowley, Gerard, De Schepper, Sebastiaan, Ge, Judy Z, Lachica, Joanne I, Toomey, Christina E, Freeman, Oliver J, Hardy, John, Barnes, Samuel J, Lashley, Tammaryn, Stevens, Beth, Chang, Sunghoe, Hong, Soyon
Published in The EMBO journal (01.09.2024)
Published in The EMBO journal (01.09.2024)
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Journal Article
Astrocyte-derived MFG-E8 facilitates microglial synapse elimination in Alzheimer's disease mouse models
Sokolova, Dimitra, Ghansah, Shari Addington, Puletti, Francesca, Georgiades, Tatiana, De Schepper, Sebastiaan, Zheng, Yongjing, Crowley, Gerard, Wu, Ling, Rueda-Carrasco, Javier, Koutsiouroumpa, Angeliki, Muckett, Philip, Freeman, Oliver J, Khakh, Baljit S, Hong, Soyon
Published in bioRxiv (01.09.2024)
Published in bioRxiv (01.09.2024)
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Journal Article
THERAPEUTIC TARGET AND MONOCLONAL ANTIBODIES AGAINST IT FOR THE DIAGNOSIS AND TREATMENT OF ALZHEIMER'S DISEASE
DOMÍNGUEZ RODRÍGUEZ, Mercedes, MARTIN BERMEJO, María Jesús, RUEDA CARRASCO, Javier, BOVOLENTA NICOLAO, Paola, MORENO IRUELA, Inmaculada, MATEO RUIZ, María Inés, ESTEVE PASTOR, María Pilar
Year of Publication 31.03.2022
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Year of Publication 31.03.2022
Patent
THERAPEUTIC TARGET AND MONOCLONAL ANTIBODIES AGAINST IT FOR THE DIAGNOSIS AND TREATMENT OF ALZHEIMER´S DISEASE
DOMÍNGUEZ RODRÍGUEZ, Mercedes, MARTIN BERMEJO, María Jesús, RUEDA CARRASCO, Javier, BOVOLENTA NICOLAO, Paola, MORENO IRUELA, Inmaculada, MATEO RUIZ, María Inés, ESTEVE PASTOR, María Pilar
Year of Publication 20.08.2020
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Year of Publication 20.08.2020
Patent
THERAPEUTIC TARGET AND MONOCLONAL ANTIBODIES AGAINST IT FOR THE DIAGNOSIS AND TREATMENT OF ALZHEIMER´S DISEASE
MARTIN BERMEJO, María Jesús, DOMINGUEZ RODRIGUEZ, Mercedes, RUEDA CARRASCO, Javier, BOVOLENTA NICOLAO, Paola, ESTEVE PASTOR, Pilar, MORENO IRUELA, Inmaculada, MATEO RUIZ, María Inés
Year of Publication 19.08.2020
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Year of Publication 19.08.2020
Patent
Sfrp1 deficiency makes retinal photoreceptors prone to degeneration
Cisneros, Elsa, Fabiana Di Marco, Rueda-Carrasco, Javier, Lillo, Concepcion, Pereyra, Guadalupe, Maria Jesus Martin-Bermejo, Vargas, Alba, Sanchez, Rocio, Sandonis, Africa, Esteve, Pilar, Bovolenta, Poala
Published in bioRxiv (09.03.2020)
Published in bioRxiv (09.03.2020)
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Paper
SFRP1 shapes astrocyte to microglia cross-talk in acute and chronic neuroinflammation
Rueda-Carrasco, Javier, Mateo, María Inés, Borroto, Aldo, María Jesús Martin-Bermejo, Kummer, Markus P, Schwartz, Stephanie, López-Atalaya, José P, Alarcon, Balbino, Heneka, Michael T, Esteve, Pilar, Bovolenta, Paola
Published in bioRxiv (24.09.2020)
Published in bioRxiv (24.09.2020)
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Paper