DNA stretching induces Cas9 off-target activity
Newton, Matthew D, Taylor, Benjamin J, Driessen, Rosalie P C, Roos, Leonie, Cvetesic, Nevena, Allyjaun, Shenaz, Lenhard, Boris, Cuomo, Maria Emanuela, Rueda, David S
Published in Nature structural & molecular biology (01.03.2019)
Published in Nature structural & molecular biology (01.03.2019)
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Journal Article
Structure and dynamics of the yeast SWR1-nucleosome complex
Willhoft, Oliver, Ghoneim, Mohamed, Lin, Chia-Liang, Chua, Eugene Y D, Wilkinson, Martin, Chaban, Yuriy, Ayala, Rafael, McCormack, Elizabeth A, Ocloo, Lorraine, Rueda, David S, Wigley, Dale B
Published in Science (American Association for the Advancement of Science) (12.10.2018)
Published in Science (American Association for the Advancement of Science) (12.10.2018)
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Journal Article
Retroviral integration into nucleosomes through DNA looping and sliding along the histone octamer
Wilson, Marcus D, Renault, Ludovic, Maskell, Daniel P, Ghoneim, Mohamed, Pye, Valerie E, Nans, Andrea, Rueda, David S, Cherepanov, Peter, Costa, Alessandro
Published in Nature communications (13.09.2019)
Published in Nature communications (13.09.2019)
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Journal Article
A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules
Gutierrez-Escribano, Pilar, Newton, Matthew D, Llauró, Aida, Huber, Jonas, Tanasie, Loredana, Davy, Joseph, Aly, Isabel, Aramayo, Ricardo, Montoya, Alex, Kramer, Holger, Stigler, Johannes, Rueda, David S, Aragon, Luis
Published in Science advances (01.11.2019)
Published in Science advances (01.11.2019)
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Journal Article
Generation of versatile ss-dsDNA hybrid substrates for single-molecule analysis
Belan, Ondrej, Moore, George, Kaczmarczyk, Artur, Newton, Matthew D., Anand, Roopesh, Boulton, Simon J., Rueda, David S.
Published in STAR protocols (18.06.2021)
Published in STAR protocols (18.06.2021)
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Journal Article
POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
Belan, Ondrej, Sebald, Marie, Adamowicz, Marek, Anand, Roopesh, Vancevska, Aleksandra, Neves, Joana, Grinkevich, Vera, Hewitt, Graeme, Segura-Bayona, Sandra, Bellelli, Roberto, Robinson, Helen M.R., Higgins, Geoff S., Smith, Graeme C.M., West, Stephen C., Rueda, David S., Boulton, Simon J.
Published in Molecular cell (15.12.2022)
Published in Molecular cell (15.12.2022)
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Journal Article
HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51
Anand, Roopesh, Buechelmaier, Erika, Belan, Ondrej, Newton, Matthew, Vancevska, Aleksandra, Kaczmarczyk, Artur, Takaki, Tohru, Rueda, David S, Powell, Simon N, Boulton, Simon J
Published in Nature (London) (13.01.2022)
Published in Nature (London) (13.01.2022)
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Journal Article
Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins
Belan, Ondrej, Barroso, Consuelo, Kaczmarczyk, Artur, Anand, Roopesh, Federico, Stefania, O’Reilly, Nicola, Newton, Matthew D., Maeots, Erik, Enchev, Radoslav I., Martinez-Perez, Enrique, Rueda, David S., Boulton, Simon J.
Published in Molecular cell (04.03.2021)
Published in Molecular cell (04.03.2021)
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Journal Article
A Minimal Load-and-Lock Ru II Luminescent DNA Probe
Newton, Matthew D, Fairbanks, Simon D, Thomas, Jim A, Rueda, David S
Published in Angewandte Chemie International Edition (13.09.2021)
Published in Angewandte Chemie International Edition (13.09.2021)
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Journal Article
Cas12a target search and cleavage on force-stretched DNA
Losito, Marialucrezia, Smith, Quentin M, Newton, Matthew D, Cuomo, Maria Emanuela, Rueda, David S
Published in Physical chemistry chemical physics : PCCP (08.12.2021)
Published in Physical chemistry chemical physics : PCCP (08.12.2021)
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Journal Article
Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein
Belan, Ondrej, Greenhough, Luke, Kuhlen, Lucas, Anand, Roopesh, Kaczmarczyk, Artur, Gruszka, Dominika T, Yardimci, Hasan, Zhang, Xiaodong, Rueda, David S, West, Stephen C, Boulton, Simon J
Published in Molecular cell (17.08.2023)
Published in Molecular cell (17.08.2023)
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Journal Article
Single-Molecule RNA Imaging Using Mango II Arrays
Cawte, Adam D, Iino, Haruki, Unrau, Peter J, Rueda, David S
Published in Methods in molecular biology (Clifton, N.J.) (2022)
Published in Methods in molecular biology (Clifton, N.J.) (2022)
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Journal Article
Negative DNA supercoiling induces genome-wide Cas9 off-target activity
Newton, Matthew D., Losito, Marialucrezia, Smith, Quentin M., Parnandi, Nishita, Taylor, Benjamin J., Akcakaya, Pinar, Maresca, Marcello, van Eijk, Patrick, Reed, Simon H., Boulton, Simon J., King, Graeme A., Cuomo, Maria Emanuela, Rueda, David S.
Published in Molecular cell (05.10.2023)
Published in Molecular cell (05.10.2023)
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Journal Article
A Minimal Load‐and‐Lock RuII Luminescent DNA Probe
Newton, Matthew D., Fairbanks, Simon D., Thomas, Jim A., Rueda, David S.
Published in Angewandte Chemie International Edition (13.09.2021)
Published in Angewandte Chemie International Edition (13.09.2021)
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Journal Article