Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials
JOHNSON, J. I, DECKER, S, SAUSVILLE, E. A, ZAHAREVITZ, D, RUBINSTEIN, L. V, VENDITTI, J. M, SCHEPARTZ, S, KALYANDRUG, S, CHRISTIAN, M, ARBUCK, S, HOLLINGSHEAD, M
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Ado-trastuzumab emtansine (T-DM1) in patients with HER2-amplified tumors excluding breast and gastric/gastroesophageal junction (GEJ) adenocarcinomas: results from the NCI-MATCH trial (EAY131) subprotocol Q
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Published in Annals of oncology (01.11.2019)
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Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines
Rubinstein, L V, Shoemaker, R H, Paull, K D, Simon, R M, Tosini, S, Skehan, P, Scudiero, D A, Monks, A, Boyd, M R
Published in JNCI : Journal of the National Cancer Institute (04.07.1990)
Published in JNCI : Journal of the National Cancer Institute (04.07.1990)
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NCI-MATCH Arms N & P: Phase II study of PI3K beta inhibitor GSK2636771 in patients (pts) with cancers (ca) with PTEN mutation/deletion (mut/del) or PTEN protein loss
Janku, F, Jegede, O, Puhalla, S L, Konstantinopoulos, P, Meric-Bernstam, F, Mitchell, E P, Zwiebel, J A, McShane, L M, Li, S, Rubinstein, L V, Doyle, L A, Patton, D, Conley, B A, O'Dwyer, P J, Harris, L N, Arteaga, C, Williams, P M, Hamilton, S R, Chen, A P, Flaherty, K T
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Crizotinib in patients with tumors harboring ALK or ROS1 rearrangements in the NCI-MATCH trial
Mansfield, A. S., Wei, Z., Mehra, R., Shaw, A. T., Lieu, C. H., Forde, P. M., Drilon, A. E., Mitchell, E. P., Wright, J. J., Takebe, N., Sharon, E., Hovelson, D., Tomlins, S., Zeng, J., Poorman, K., Malik, N., Gray, R. J., Li, S., McShane, L. M., Rubinstein, L. V., Patton, D., Williams, P. M., Hamilton, S. R., Conley, B. A., Arteaga, C. L., Harris, L. N., O’Dwyer, P. J., Chen, A. P., Flaherty, K. T.
Published in NPJ precision oncology (01.03.2022)
Published in NPJ precision oncology (01.03.2022)
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Neural Computing in Cancer Drug Development: Predicting Mechanism of Action
Weinstein, John N., Kohn, Kurt W., Grever, Michael R., Viswanadhan, Vellarkad N., Rubinstein, Lawrence V., Monks, Anne P., Scudiero, Dominic A., Welch, Lester, Koutsoukos, Antonis D., Chiausa, August J., Paull, Kenneth D.
Published in Science (American Association for the Advancement of Science) (16.10.1992)
Published in Science (American Association for the Advancement of Science) (16.10.1992)
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Preclinical antitumor activity of temozolomide in mice : efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1-nitrosourea
PLOWMAN, J, WAUD, W. R, KOUTSOUKOS, A. D, RUBINSTEIN, L. V, MOORE, T. D, GREVER, M. R
Published in Cancer research (Chicago, Ill.) (15.07.1994)
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Published in Cancer research (Chicago, Ill.) (15.07.1994)
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Enhanced sensitivity to 1-β-D-arabinofuranosylcytosine and topoisomerase II inhibitors in tumor cell lines harboring activated ras oncogenes
KOO, H.-M, MONKS, A, ZARBL, H, VANDE WOUDE, G. F, MIKHEEV, A, RUBINSTEIN, L. V, GRAY-GOODRICH, M, MCWILLIAMS, M. J, ALVORD, W. G, OIE, H. K, GAZDAR, A. F, PAULL, K. D
Published in Cancer research (Chicago, Ill.) (15.11.1996)
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Published in Cancer research (Chicago, Ill.) (15.11.1996)
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Multidrug-resistant phenotype of disease-oriented panels of human tumor cell lines used for anticancer drug screening
LIN WU, SMYTHE, A. M, SHOEMAKER, R. H, STINSON, S. F, MULLENDORE, L. A, MONKS, A, SCUDIERO, D. A, PAULL, K. D, KOUTSOUKOS, A. D, RUBINSTEIN, L. V, BOYD, M. R
Published in Cancer research (Chicago, Ill.) (01.06.1992)
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Published in Cancer research (Chicago, Ill.) (01.06.1992)
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Predictive statistics and artificial intelligence in the U.S. National Cancer Institute's Drug Discovery Program for Cancer and AIDS
Weinstein, J N, Myers, T, Buolamwini, J, Raghavan, K, van Osdol, W, Licht, J, Viswanadhan, V N, Kohn, K W, Rubinstein, L V, Koutsoukos, A D
Published in Stem cells (Dayton, Ohio) (01.01.1994)
Published in Stem cells (Dayton, Ohio) (01.01.1994)
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Vaginal Clear Cell Adenocarcinoma in the United States
Trimble, Edward L., Rubinstein, Lawrence V., Menck, Herman R., Hankey, Benjamin F., Kosary, Carol, Giusti, Ruthann M.
Published in Gynecologic oncology (01.04.1996)
Published in Gynecologic oncology (01.04.1996)
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Pilot study of interleukin-2 and lymphokine-activated killer cells combined with immunomodulatory doses of chemotherapy and sequenced with interferon alfa-2a in patients with metastatic melanoma and renal cell carcinoma
Sznol, M, Clark, J W, Smith, 2nd, J W, Steis, R G, Urba, W J, Rubinstein, L V, VanderMolen, L A, Janik, J, Sharfman, W H, Fenton, R G
Published in JNCI : Journal of the National Cancer Institute (17.06.1992)
Published in JNCI : Journal of the National Cancer Institute (17.06.1992)
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Ipatasertib in Patients with Tumors with AKT Mutations: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Sub-protocol Z1K
Kalinsky, K., Zihan, W., McCourt, C., Mitchell, E.P., Wright, J.J., Doyle, L.A., Gray, R.J., Wang, V., McShane, L.M., Rubinstein, L.V., Patton, D., Williams, P.M., Hamilton, S.R., Conley, B.A., Arteaga, C.A., Harris, L.N., O’Dwyer, P.J., Chen, A.P., Flaherty, K.T.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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Application of molecular profiling in clinical trials for advanced metastatic cancers
Kummar, Shivaani, Williams, P Mickey, Lih, Chih-Jian, Polley, Eric C, Chen, Alice P, Rubinstein, Larry V, Zhao, Yingdong, Simon, Richard M, Conley, Barbara A, Doroshow, James H
Published in JNCI : Journal of the National Cancer Institute (01.04.2015)
Published in JNCI : Journal of the National Cancer Institute (01.04.2015)
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Phase II trial of afatinib in patients with EGFR-mutated solid tumors excluding lung cancer: results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol A
Reckamp, K., Song, Z., Gettinger, S., Mitchell, E.P., Wright, J.J., Moscow, J.A., Gray, R.J., Wang, V., McShane, L.M., Rubinstein, L.V., Patton, D.R., Williams, P.M., Hamilton, S.R., Conley, B.A., Arteaga, C.L., Harris, L.N., O’Dwyer, P.J., Chen, A.P., Flaherty, K.T.
Published in European journal of cancer (1990) (01.10.2022)
Published in European journal of cancer (1990) (01.10.2022)
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