MF63 [2-(6-Chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a Selective Microsomal Prostaglandin E Synthase-1 Inhibitor, Relieves Pyresis and Pain in Preclinical Models of Inflammation
Xu, Daigen, Rowland, Steven E, Clark, Patsy, Giroux, André, Côté, Bernard, Guiral, Sébastien, Salem, Myriam, Ducharme, Yves, Friesen, Richard W, Méthot, Nathalie, Mancini, Joseph, Audoly, Laurent, Riendeau, Denis
Published in The Journal of pharmacology and experimental therapeutics (01.09.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2008)
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Journal Article
MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a Selective E Prostanoid Receptor 4 Antagonist, Relieves Joint Inflammation and Pain in Rodent Models of Rheumatoid and Osteoarthritis
Clark, Patsy, Rowland, Steven E, Denis, Danielle, Mathieu, Marie-Claude, Stocco, Rino, Poirier, Hugo, Burch, Jason, Han, Yongxin, Audoly, Laurent, Therien, Alex G, Xu, Daigen
Published in The Journal of pharmacology and experimental therapeutics (01.05.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2008)
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Journal Article
Pharmacological characterization of a selective COX-2 inhibitor MF-tricyclic, [3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone], in multiple preclinical species
Rowland, Steven E., Clark, Patsy, Gordon, Robert, Mullen, Anne K., Guay, Jocelyne, Dufresne, Lynn, Brideau, Christine, Cote, Bernard, Ducharme, Yves, Mancini, Joseph, Chan, Chi-chung, Audoly, Laurent, Xu, Daigen
Published in European journal of pharmacology (10.04.2007)
Published in European journal of pharmacology (10.04.2007)
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