GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers
Sabbatini, Peter, Korenchuk, Susan, Rowand, Jason L, Groy, Arthur, Liu, Qi, Leperi, Dominic, Atkins, Charity, Dumble, Melissa, Yang, Jingsong, Anderson, Kelly, Kruger, Ryan G, Gontarek, Richard R, Maksimchuk, Kenneth R, Suravajjala, Sapna, Lapierre, Russell R, Shotwell, J Brad, Wilson, Joseph W, Chamberlain, Stanley D, Rabindran, Sridhar K, Kumar, Rakesh
Published in Molecular cancer therapeutics (01.10.2009)
Published in Molecular cancer therapeutics (01.10.2009)
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Antitumor Activity of GSK1904529A, a Small-molecule Inhibitor of the Insulin-like Growth Factor-I Receptor Tyrosine Kinase
Sabbatini, Peter, Rowand, Jason L, Groy, Arthur, Korenchuk, Susan, Liu, Qi, Atkins, Charity, Dumble, Melissa, Yang, Jingsong, Anderson, Kelly, Wilson, Brian J, Emmitte, Kyle A, Rabindran, Sridhar K, Kumar, Rakesh
Published in Clinical cancer research (01.05.2009)
Published in Clinical cancer research (01.05.2009)
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Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity
Chamberlain, Stanley D, Redman, Anikó M, Wilson, Joseph W, Deanda, Felix, Shotwell, J Brad, Gerding, Roseanne, Lei, Huangshu, Yang, Bin, Stevens, Kirk L, Hassell, Anne M, Shewchuk, Lisa M, Leesnitzer, M Anthony, Smith, Jeffery L, Sabbatini, Peter, Atkins, Charity, Groy, Arthur, Rowand, Jason L, Kumar, Rakesh, Mook, Jr, Robert A, Moorthy, Ganesh, Patnaik, Samarjit
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
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Endothelial cells in peripheral blood of healthy subjects and patients with metastatic carcinomas
Rowand, Jason L., Martin, Grace, Doyle, Gerald V., Miller, M. Craig, Pierce, Michael S., Connelly, Mark C., Rao, Chandra, Terstappen, Leon W. M. M.
Published in Cytometry. Part A (01.02.2007)
Published in Cytometry. Part A (01.02.2007)
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Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines : Potent inhibitors of the IGF-1R receptor tyrosine kinase
CHAMBERLAIN, Stanley D, WILSON, Joseph W, ATKINS, Charity, GERDING, Roseanne, HASSELL, Anne M, HUANGSHU LEI, MOCK, Robert A, MOORTHY, Ganesh, ROWAND, Jason L, STEVENS, Kirk L, KUMAR, Rakesh, BRAD SHOTWELL, J, DEANDA, Felix, PATNAIK, Samarjit, REDMAN, Aniko M, BIN YANG, SHEWCHUK, Lisa, SABBATINI, Peter, LEESNITZER, M. Anthony, GROY, Arthur
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
Published in Bioorganic & medicinal chemistry letters (15.01.2009)
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Discovery and optimization of imidazo[1,2- a]pyridine inhibitors of insulin-like growth factor-1 receptor (IGF-1R)
Emmitte, Kyle A., Wilson, Brian J., Baum, Erich W., Emerson, Holly K., Kuntz, Kevin W., Nailor, Kristen E., Salovich, James M., Smith, Stephon C., Cheung, Mui, Gerding, Roseanne M., Stevens, Kirk L., Uehling, David E., Mook, Robert A., Moorthy, Ganesh S., Dickerson, Scott H., Hassell, Anne M., Anthony Leesnitzer, M., Shewchuk, Lisa M., Groy, Arthur, Rowand, Jason L., Anderson, Kelly, Atkins, Charity L., Yang, Jingsong, Sabbatini, Peter, Kumar, Rakesh
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
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Journal Article
Antitumor Activity of GSK1904529A, a Small-molecule Inhibitor of the Insulin-like Growth Factor-I ReceptorTyrosine Kinase
SABBATINI, Peter, ROWAND, Jason L, EMMITTE, Kyle A, RABINDRAN, Sridhar K, KUMAR, Rakesh, GROY, Arthur, KORENCHUK, Susan, QI LIU, ATKINS, Charity, DUMBLE, Melissa, JINGSONG YANG, ANDERSON, Kelly, WILSON, Brian J
Published in Clinical cancer research (2009)
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Published in Clinical cancer research (2009)
Journal Article
Optimization of 4,6-bis-anilino-1 H-pyrrolo[2,3- d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity
Chamberlain, Stanley D., Redman, Anikó M., Wilson, Joseph W., Deanda, Felix, Shotwell, J. Brad, Gerding, Roseanne, Lei, Huangshu, Yang, Bin, Stevens, Kirk L., Hassell, Anne M., Shewchuk, Lisa M., Leesnitzer, M. Anthony, Smith, Jeffery L., Sabbatini, Peter, Atkins, Charity, Groy, Arthur, Rowand, Jason L., Kumar, Rakesh, Mook, Robert A., Moorthy, Ganesh, Patnaik, Samarjit
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
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Journal Article
Optimization of 4,6-bis-anilmo-1H-pyrrolo[2,3-d]pyrimidme IGF-1R tyrosine kinase inhibitors towards JNK selectivity
CHAMBERLAIN, Stanley D, REDMAN, Aniko M, SHEWCHUK, Lisa M, LEESNITZER, M. Anthony, SMITH, Jeffery L, SABBATINI, Peter, ATKINS, Charity, GROY, Arthur, ROWAND, Jason L, KUMAR, Rakesh, MOOK, Robert A, MOORTHY, Ganesh, WILSON, Joseph W, PATNAIK, Samarjit, DEANDA, Felix, SHOTWELL, J. Brad, GERDING, Roseanne, HUANGSHU LEI, BIN YANG, STEVENS, Kirk L, HASSELL, Anne M
Published in Bioorganic & medicinal chemistry letters (2009)
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Published in Bioorganic & medicinal chemistry letters (2009)
Journal Article
Discovery of 4,6-bis-anilino-1 H-pyrrolo[2,3- d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase
Chamberlain, Stanley D., Wilson, Joseph W., Deanda, Felix, Patnaik, Samarjit, Redman, Anikó M., Yang, Bin, Shewchuk, Lisa, Sabbatini, Peter, Leesnitzer, M. Anthony, Groy, Arthur, Atkins, Charity, Gerding, Roseanne, Hassell, Anne M., Lei, Huangshu, Mook, Robert A., Moorthy, Ganesh, Rowand, Jason L., Stevens, Kirk L., Kumar, Rakesh, Shotwell, J. Brad
Published in Bioorganic & medicinal chemistry letters (2009)
Published in Bioorganic & medicinal chemistry letters (2009)
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Journal Article