Safety and efficacy of ORM-12741 on cognitive and behavioral symptoms in patients with Alzheimer's disease: A randomized, double-blind, proof-of-concept study
Rinne, J.O, Wesnes, K, Hänninen, J, Murphy, M, Riordan, H, Rouru, J, ALPO Study Group
Published in Journal of the neurological sciences (15.10.2013)
Published in Journal of the neurological sciences (15.10.2013)
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Pharmacokinetics of deramciclane and N-desmethylderamciclane after single and repeated oral doses in healthy volunteers
Huupponen, R, Anttila, M, Rouru, J, Kanerva, H, Miettinen, T, Scheinin, M
Published in International journal of clinical pharmacology and therapeutics (01.08.2004)
Published in International journal of clinical pharmacology and therapeutics (01.08.2004)
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Pharmacokinetics of oral entacapone after frequent multiple dosing and effects on levodopa disposition
ROURU, J, GORDIN, A, HUUPPONEN, R, HUHTALA, S, SAVONTAUS, E, KORPELA, K, REINIKAINEN, K, SCHEININ, M
Published in European journal of clinical pharmacology (01.08.1999)
Published in European journal of clinical pharmacology (01.08.1999)
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2-[18F]fluoro-2-deoxy-d-glucose combined with microdialysis can be used for the comparison of tissue glucose metabolism in obese and lean rats
Virtanen, K. A., Haaparanta, M., Grönroos, T., Bergman, J., Solin, O., Rouru, J., Nuutila, P., Huupponen, R.
Published in Diabetes, obesity & metabolism (01.01.2002)
Published in Diabetes, obesity & metabolism (01.01.2002)
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Journal Article
Pharmacokinetics and safety of deramciclane during multiple oral dosing
Kanerva, H, Kilkku, O, Helminen, A, Rouru, J, Scheinin, M, Huupponen, R, Klebovich, I, Drabant, S, Urtti, A
Published in International journal of clinical pharmacology and therapeutics (01.12.1999)
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Published in International journal of clinical pharmacology and therapeutics (01.12.1999)
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Effects of estrous cycle and steroid replacement on the expression of leptin and uncoupling proteins in adipose tissue in the rat
Luukkaa, V, Savontaus, E, Rouru, J, Virtanen, K A, Boss, O, Huhtaniemi, I, Koulu, M, Pesonen, U, Huupponen, R
Published in Gynecological endocrinology (01.04.2001)
Published in Gynecological endocrinology (01.04.2001)
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Journal Article
Effects of metformin treatment on glucose transporter proteins in subcellular fractions of skeletal muscle in (fa/fa) Zucker rats
Rouru, J., Peltonen, J., Hänninen, V., Pesonen, U., Huupponen, R., Koulu, M., Santti, E.
Published in British journal of pharmacology (01.08.1995)
Published in British journal of pharmacology (01.08.1995)
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Journal Article
A double-blind, randomized, placebo-controlled crossover trial of the 2C-adrenoceptor antagonist ORM-12741 for prevention of cold-induced vasospasm in patients with systemic sclerosis
Herrick, A. L., Murray, A. K., Ruck, A., Rouru, J., Moore, T. L., Whiteside, J., Hakulinen, P., Wigley, F., Snapir, A.
Published in Rheumatology (Oxford, England) (01.05.2014)
Published in Rheumatology (Oxford, England) (01.05.2014)
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Journal Article
Validation of [11C]ORM-13070 as a PET tracer for alpha2c-adrenoceptors in the human brain
Lehto, Jussi, Hirvonen, Mika M., Johansson, Jarkko, Kemppainen, Jukka, Luoto, Pauliina, Naukkarinen, Tarja, Oikonen, Vesa, Arponen, Eveliina, Rouru, Juha, Sallinen, Jukka, Scheinin, Harry, Vuorilehto, Lauri, Finnema, Sjoerd J., Halldin, Christer, Rinne, Juha O., Scheinin, Mika
Published in Synapse (New York, N.Y.) (01.03.2015)
Published in Synapse (New York, N.Y.) (01.03.2015)
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Journal Article
Validation of [ 11 C]ORM‐13070 as a PET tracer for alpha 2c ‐adrenoceptors in the human brain
Lehto, Jussi, Hirvonen, Mika M., Johansson, Jarkko, Kemppainen, Jukka, Luoto, Pauliina, Naukkarinen, Tarja, Oikonen, Vesa, Arponen, Eveliina, Rouru, Juha, Sallinen, Jukka, Scheinin, Harry, Vuorilehto, Lauri, Finnema, Sjoerd J., Halldin, Christer, Rinne, Juha O., Scheinin, Mika
Published in Synapse (New York, N.Y.) (01.03.2015)
Published in Synapse (New York, N.Y.) (01.03.2015)
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Journal Article
Serum leptin concentrations in women with polycystic ovary syndrome
ROURU, J, ANTTILA, L, KOSKINEN, P, PENTTILÄ, T.-A, IRJALA, K, HUUPPONEN, R, KOULU, M
Published in The journal of clinical endocrinology and metabolism (01.06.1997)
Published in The journal of clinical endocrinology and metabolism (01.06.1997)
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Journal Article
Determination of metformin in plasma by high-performance liquid chromatography
Huupponen, R., Ojala-Karlsson, P., Rouru, J., Koulu, M.
Published in Journal of chromatography (02.12.1992)
Published in Journal of chromatography (02.12.1992)
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Correlation between circulating leptin and luteinizing hormone during the menstrual cycle in normal-weight women
TEIRMAA, T, LUUKKAA, V, ROURU, J, KOULU, M, HUUPPONEN, R
Published in European journal of endocrinology (01.08.1998)
Published in European journal of endocrinology (01.08.1998)
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Journal Article
Deramciclane in the treatment of generalized anxiety disorder: A placebo-controlled, double-blind, dose-finding study
Naukkarinen, Hannu, Raassina, Roope, Penttinen, Jukka, Ahokas, Antti, Jokinen, Riitta, Koponen, Hannu, Lepola, Ulla, Kanerva, Harri, Lehtonen, Leena, Pohjalainen, Tiina, Partanen, Auli, Mäki-Ikola, Outi, Rouru, Juha
Published in European neuropsychopharmacology (01.12.2005)
Published in European neuropsychopharmacology (01.12.2005)
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