CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing
Moreno-Mateos, Miguel A., Fernandez, Juan P., Rouet, Romain, Vejnar, Charles E., Lane, Maura A., Mis, Emily, Khokha, Mustafa K., Doudna, Jennifer A., Giraldez, Antonio J.
Published in Nature communications (08.12.2017)
Published in Nature communications (08.12.2017)
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Journal Article
General strategy for the generation of human antibody variable domains with increased aggregation resistance
Dudgeon, Kip, Rouet, Romain, Kokmeijer, Iris, Schofield, Peter, Stolp, Jessica, Langley, David, Stock, Daniela, Christ, Daniel
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2012)
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Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity
Sabouri, Zahra, Schofield, Peter, Horikawa, Keisuke, Spierings, Emily, Kipling, David, Randall, Katrina L, Langley, David, Roome, Brendan, Vazquez-Lombardi, Rodrigo, Rouet, Romain, Hermes, Jana, Chan, Tyani D, Brink, Robert, Dunn-Walters, Deborah K, Christ, Daniel, Goodnow, Christopher C
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2014)
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Journal Article
Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing
Rouet, Romain, Thuma, Benjamin A, Roy, Marc D, Lintner, Nathanael G, Rubitski, David M, Finley, James E, Wisniewska, Hanna M, Mendonsa, Rima, Hirsh, Ariana, de Oñate, Lorena, Compte Barrón, Joan, McLellan, Thomas J, Bellenger, Justin, Feng, Xidong, Varghese, Alison, Chrunyk, Boris A, Borzilleri, Kris, Hesp, Kevin D, Zhou, Kaihong, Ma, Nannan, Tu, Meihua, Dullea, Robert, McClure, Kim F, Wilson, Ross C, Liras, Spiros, Mascitti, Vincent, Doudna, Jennifer A
Published in Journal of the American Chemical Society (30.05.2018)
Published in Journal of the American Chemical Society (30.05.2018)
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Journal Article
Next-Generation Sequencing of Antibody Display Repertoires
Rouet, Romain, Jackson, Katherine J L, Langley, David B, Christ, Daniel
Published in Frontiers in immunology (02.02.2018)
Published in Frontiers in immunology (02.02.2018)
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Journal Article
Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients
Rouet, Romain, Henry, Jake Y., Johansen, Matt D., Sobti, Meghna, Balachandran, Harikrishnan, Langley, David B., Walker, Gregory J., Lenthall, Helen, Jackson, Jennifer, Ubiparipovic, Stephanie, Mazigi, Ohan, Schofield, Peter, Burnett, Deborah L., Brown, Simon H. J., Martinello, Marianne, Hudson, Bernard, Gilroy, Nicole, Post, Jeffrey J., Kelleher, Anthony, Jäck, Hans-Martin, Goodnow, Christopher C., Turville, Stuart G., Rawlinson, William D., Bull, Rowena A., Stewart, Alastair G., Hansbro, Philip M., Christ, Daniel
Published in Nature communications (08.02.2023)
Published in Nature communications (08.02.2023)
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Journal Article
Long-term persistence of RBD+ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection
Abayasingam, Arunasingam, Balachandran, Harikrishnan, Agapiou, David, Hammoud, Mohamed, Rodrigo, Chaturaka, Keoshkerian, Elizabeth, Li, Hui, Brasher, Nicholas A., Christ, Daniel, Rouet, Romain, Burnet, Deborah, Grubor-Bauk, Branka, Rawlinson, William, Turville, Stuart, Aggarwal, Anupriya, Stella, Alberto Ospina, Fichter, Christina, Brilot, Fabienne, Mina, Michael, Post, Jeffrey J., Hudson, Bernard, Gilroy, Nicky, Dwyer, Dominic, Sasson, Sarah C., Tea, Fiona, Pilli, Deepti, Kelleher, Anthony, Tedla, Nicodemus, Lloyd, Andrew R., Martinello, Marianne, Bull, Rowena A.
Published in Cell reports. Medicine (20.04.2021)
Published in Cell reports. Medicine (20.04.2021)
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Journal Article
High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells
Phetsouphanh, Chansavath, Khoo, Weng Hua, Jackson, Katherine, Klemm, Vera, Howe, Annett, Aggarwal, Anupriya, Akerman, Anouschka, Milogiannakis, Vanessa, Stella, Alberto Ospina, Rouet, Romain, Schofield, Peter, Faulks, Megan L, Law, Hannah, Danwilai, Thidarat, Starr, Mitchell, Munier, C Mee Ling, Christ, Daniel, Singh, Mandeep, Croucher, Peter I, Brilot-Turville, Fabienne, Turville, Stuart, Phan, Tri Giang, Dore, Gregory J, Darley, David, Cunningham, Philip, Matthews, Gail V, Kelleher, Anthony D, Zaunders, John J
Published in Frontiers in immunology (05.12.2022)
Published in Frontiers in immunology (05.12.2022)
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Journal Article
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies
Rouet, Romain, Mazigi, Ohan, Walker, Gregory J., Langley, David B., Sobti, Meghna, Schofield, Peter, Lenthall, Helen, Jackson, Jennifer, Ubiparipovic, Stephanie, Henry, Jake Y., Abayasingam, Arunasingam, Burnett, Deborah, Kelleher, Anthony, Brink, Robert, Bull, Rowena A., Turville, Stuart, Stewart, Alastair G., Goodnow, Christopher C., Rawlinson, William D., Christ, Daniel
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
Antibody-mediated delivery of CRISPR-Cas9 ribonucleoproteins in human cells
Ubiparipovic, Stephanie, Christ, Daniel, Rouet, Romain
Published in Protein engineering, design and selection (17.02.2022)
Published in Protein engineering, design and selection (17.02.2022)
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Journal Article
I-motif DNA structures are formed in the nuclei of human cells
Zeraati, Mahdi, Langley, David B., Schofield, Peter, Moye, Aaron L., Rouet, Romain, Hughes, William E., Bryan, Tracy M., Dinger, Marcel E., Christ, Daniel
Published in Nature chemistry (01.06.2018)
Published in Nature chemistry (01.06.2018)
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Journal Article
Optimized CRISPR-Cpf1 system for genome editing in zebrafish
Fernandez, Juan P., Vejnar, Charles E., Giraldez, Antonio J., Rouet, Romain, Moreno-Mateos, Miguel A.
Published in Methods (San Diego, Calif.) (01.11.2018)
Published in Methods (San Diego, Calif.) (01.11.2018)
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Journal Article
Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability
Burnett, Deborah L., Jackson, Katherine J.L., Langley, David B., Aggarwal, Anupriya, Stella, Alberto Ospina, Johansen, Matt D., Balachandran, Harikrishnan, Lenthall, Helen, Rouet, Romain, Walker, Gregory, Saunders, Bernadette M., Singh, Mandeep, Li, Hui, Henry, Jake Y., Jackson, Jennifer, Stewart, Alastair G., Witthauer, Franka, Spence, Matthew A., Hansbro, Nicole G., Jackson, Colin, Schofield, Peter, Milthorpe, Claire, Martinello, Marianne, Schulz, Sebastian R., Roth, Edith, Kelleher, Anthony, Emery, Sean, Britton, Warwick J., Rawlinson, William D., Karl, Rudolfo, Schäfer, Simon, Winkler, Thomas H., Brink, Robert, Bull, Rowena A., Hansbro, Philip M., Jäck, Hans-Martin, Turville, Stuart, Christ, Daniel, Goodnow, Christopher C.
Published in Immunity (Cambridge, Mass.) (14.12.2021)
Published in Immunity (Cambridge, Mass.) (14.12.2021)
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Journal Article
Human genomic DNA is widely interspersed with i-motif structures
Peña Martinez, Cristian David, Zeraati, Mahdi, Rouet, Romain, Mazigi, Ohan, Henry, Jake Y, Gloss, Brian, Kretzmann, Jessica A, Evans, Cameron W, Ruggiero, Emanuela, Zanin, Irene, Marušič, Maja, Plavec, Janez, Richter, Sara N, Bryan, Tracy M, Smith, Nicole M, Dinger, Marcel E, Kummerfeld, Sarah, Christ, Daniel
Published in The EMBO journal (15.10.2024)
Published in The EMBO journal (15.10.2024)
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