Differing roles for short chain fatty acids and GPR43 agonism in the regulation of intestinal barrier function and immune responses
D'Souza, Warren N, Douangpanya, Jason, Mu, Sharon, Jaeckel, Peter, Zhang, Ming, Maxwell, Joseph R, Rottman, James B, Labitzke, Katja, Willee, Angela, Beckmann, Holger, Wang, Yingcai, Li, Yang, Schwandner, Ralf, Johnston, James A, Towne, Jennifer E, Hsu, Hailing
Published in PloS one (20.07.2017)
Published in PloS one (20.07.2017)
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A multicenter phase 1 study of solitomab (MT110, AMG 110), a bispecific EpCAM/CD3 T-cell engager (BiTE®) antibody construct, in patients with refractory solid tumors
Kebenko, Maxim, Goebeler, Marie-Elisabeth, Wolf, Martin, Hasenburg, Annette, Seggewiss-Bernhardt, Ruth, Ritter, Barbara, Rautenberg, Beate, Atanackovic, Djordje, Kratzer, Andrea, Rottman, James B., Friedrich, Matthias, Vieser, Eva, Elm, Stefanie, Patzak, Ingrid, Wessiepe, Dorothea, Stienen, Sabine, Fiedler, Walter
Published in Oncoimmunology (01.01.2018)
Published in Oncoimmunology (01.01.2018)
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Global Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to pain
Gingras, Jacinthe, Smith, Sarah, Matson, David J, Johnson, Danielle, Nye, Kim, Couture, Lauren, Feric, Elma, Yin, Ruoyuan, Moyer, Bryan D, Peterson, Matthew L, Rottman, James B, Beiler, Rudolph J, Malmberg, Annika B, McDonough, Stefan I
Published in PloS one (04.09.2014)
Published in PloS one (04.09.2014)
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Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity
Kim, Hye Young, PhD, Chang, Ya-Jen, PhD, Subramanian, Srividya, PhD, Lee, Hyun-Hee, PhD, Albacker, Lee A., PhD, Matangkasombut, Ponpan, MD, PhD, Savage, Paul B., PhD, McKenzie, Andrew N.J., PhD, Smith, Dirk E., MS, Rottman, James B., DVM, PhD, DeKruyff, Rosemarie H., PhD, Umetsu, Dale T., MD, PhD
Published in Journal of allergy and clinical immunology (01.01.2012)
Published in Journal of allergy and clinical immunology (01.01.2012)
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Identification of Functional Roles for Both IL-17RB and IL-17RA in Mediating IL-25-Induced Activities
Rickel, Erika A, Siegel, Lori A, Yoon, Bo-Rin Park, Rottman, James B, Kugler, David G, Swart, David A, Anders, Penny M, Tocker, Joel E, Comeau, Michael R, Budelsky, Alison L
Published in The Journal of immunology (1950) (15.09.2008)
Published in The Journal of immunology (1950) (15.09.2008)
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Immunogenicity/hypersensitivity of biologics
Leach, Michael W, Rottman, James B, Hock, M Benjamin, Finco, Deborah, Rojko, Jennifer L, Beyer, Joseph C
Published in Toxicologic pathology (01.01.2014)
Published in Toxicologic pathology (01.01.2014)
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T-SIGn tumor reengineering therapy and CAR T cells synergize in combination therapy to clear human lung tumor xenografts and lung metastases in NSG mice
Sonzogni, Olmo, Zak, Daniel E., Sasso, Maria Stella, Lear, Rochelle, Muntzer, Alice, Zonca, Manuela, West, Katy, Champion, Brian R., Rottman, James B.
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
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Validation of a DKK1 RNAscope chromogenic in situ hybridization assay for gastric and gastroesophageal junction adenocarcinoma tumors
Caldwell, Charles, Rottman, James B, Paces, Will, Bueche, Elizabeth, Reitsma, Sofia, Gibb, Joseph, Adisetiyo, Vitria, Haas, Michael S, Heath, Heidi, Newman, Walter, Baum, Jason, Gianani, Roberto, Kagey, Michael H
Published in Scientific reports (10.05.2021)
Published in Scientific reports (10.05.2021)
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Large-scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes
Tyler, Matthew A., MD, Russell, Chris B., PhD, Smith, Dirk E., MSc, Rottman, James B., DVM, PhD, Padro Dietz, Caroline J., PhD, Hu, Xuguang, PhD, Citardi, Martin J., MD, Fakhri, Samer, MD, Assassi, Shervin, MD, Luong, Amber, MD, PhD
Published in Journal of allergy and clinical immunology (01.03.2017)
Published in Journal of allergy and clinical immunology (01.03.2017)
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Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation
Maxwell, Joseph R., Zhang, Yu, Brown, William A., Smith, Carole L., Byrne, Fergus R., Fiorino, Mike, Stevens, Erin, Bigler, Jeannette, Davis, John A., Rottman, James B., Budelsky, Alison L., Symons, Antony, Towne, Jennifer E.
Published in Immunity (Cambridge, Mass.) (20.10.2015)
Published in Immunity (Cambridge, Mass.) (20.10.2015)
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IL-22 regulates iron availability in vivo through the induction of hepcidin
Smith, Carole L, Arvedson, Tara L, Cooke, Keegan S, Dickmann, Leslie J, Forte, Carla, Li, Hongyan, Merriam, Kimberly L, Perry, V Kristina, Tran, Linh, Rottman, James B, Maxwell, Joseph R
Published in The Journal of immunology (1950) (15.08.2013)
Published in The Journal of immunology (1950) (15.08.2013)
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Design of an Interferon-Resistant Oncolytic HSV-1 Incorporating Redundant Safety Modalities for Improved Tolerability
Kennedy, Edward M., Farkaly, Terry, Grzesik, Peter, Lee, Jennifer, Denslow, Agnieszka, Hewett, Jacqueline, Bryant, Jeffrey, Behara, Prajna, Goshert, Caitlin, Wambua, Daniel, De Almeida, Ana, Jacques, Judith, Deavall, Damian, Rottman, James B., Glorioso, Joseph C., Finer, Mitchell H., Haines, Brian B., Quéva, Christophe, Lerner, Lorena
Published in Molecular therapy. Oncolytics (25.09.2020)
Published in Molecular therapy. Oncolytics (25.09.2020)
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Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection
Hancock, Wayne W, Özkaynak, Engin, Gao, Wei, Shemmeri, Nida, Wang, Chichung, Gutierrez-Ramos, Jose-Carlos, Amaral, Jillian, Qin, Shixin, Rottman, James B, Coyle, Anthony J
Published in Nature immunology (01.07.2001)
Published in Nature immunology (01.07.2001)
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Programmed Death-1 Targeting Can Promote Allograft Survival
Ozkaynak, Engin, Wang, Liqing, Goodearl, Andrew, McDonald, Kevin, Qin, Shixin, O'Keefe, Theresa, Duong, Thao, Smith, Tammy, Gutierrez-Ramos, Jose-Carlos, Rottman, James B, Coyle, Anthony J, Hancock, Wayne W
Published in The Journal of immunology (1950) (01.12.2002)
Published in The Journal of immunology (1950) (01.12.2002)
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Broad Antitumor Activity in Breast Cancer Xenografts by Motesanib, a Highly Selective, Oral Inhibitor of Vascular Endothelial Growth Factor, Platelet-Derived Growth Factor, and Kit Receptors
Coxon, Angela, Bush, Tammy, Saffran, Douglas, Kaufman, Stephen, Belmontes, Brian, Rex, Karen, Hughes, Paul, Caenepeel, Sean, Rottman, James B, Tasker, Andrew, Patel, Vinod, Kendall, Richard, Radinsky, Robert, Polverino, Anthony
Published in Clinical cancer research (01.01.2009)
Published in Clinical cancer research (01.01.2009)
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The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE
Rottman, James B, Smith, Tammy, Tonra, James R, Ganley, Kenneth, Bloom, Troy, Silva, Robert, Pierce, Barbara, Gutierrez-Ramos, Jose-Carlos, Özkaynak, Engin, Coyle, Anthony J
Published in Nature immunology (01.07.2001)
Published in Nature immunology (01.07.2001)
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Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models
Killion, Elizabeth A, Wang, Jinghong, Yie, Junming, Shi, Stone D-H, Bates, Darren, Min, Xiaoshan, Komorowski, Renee, Hager, Todd, Deng, Liying, Atangan, Larissa, Lu, Shu-Chen, Kurzeja, Robert J M, Sivits, Glenn, Lin, Joanne, Chen, Qing, Wang, Zhulun, Thibault, Stephen A, Abbott, Christina M, Meng, Tina, Clavette, Brandon, Murawsky, Christopher M, Foltz, Ian N, Rottman, James B, Hale, Clarence, Véniant, Murielle M, Lloyd, David J
Published in Science translational medicine (19.12.2018)
Published in Science translational medicine (19.12.2018)
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Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals
Mylonakis, Eleftherios, Idnurm, Alexander, Moreno, Roberto, El Khoury, Joseph, Rottman, James B., Ausubel, Frederick M., Heitman, Joseph, Calderwood, Stephen B.
Published in Molecular microbiology (01.10.2004)
Published in Molecular microbiology (01.10.2004)
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Safety, Efficacy, and Biomarker Results from a Phase Ib Study of the Anti-DKK1 Antibody DKN-01 in Combination with Pembrolizumab in Advanced Esophagogastric Cancers
Klempner, Samuel J, Bendell, Johanna C, Villaflor, Victoria Meucci, Tenner, Laura LaNiel, Stein, Stacey M, Rottman, James B, Naik, Girish S, Sirard, Cynthia A, Kagey, Michael H, Chaney, Marya F, Strickler, John H
Published in Molecular cancer therapeutics (01.11.2021)
Published in Molecular cancer therapeutics (01.11.2021)
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