Differing roles for short chain fatty acids and GPR43 agonism in the regulation of intestinal barrier function and immune responses
D'Souza, Warren N, Douangpanya, Jason, Mu, Sharon, Jaeckel, Peter, Zhang, Ming, Maxwell, Joseph R, Rottman, James B, Labitzke, Katja, Willee, Angela, Beckmann, Holger, Wang, Yingcai, Li, Yang, Schwandner, Ralf, Johnston, James A, Towne, Jennifer E, Hsu, Hailing
Published in PloS one (20.07.2017)
Published in PloS one (20.07.2017)
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Global Nav1.7 knockout mice recapitulate the phenotype of human congenital indifference to pain
Gingras, Jacinthe, Smith, Sarah, Matson, David J, Johnson, Danielle, Nye, Kim, Couture, Lauren, Feric, Elma, Yin, Ruoyuan, Moyer, Bryan D, Peterson, Matthew L, Rottman, James B, Beiler, Rudolph J, Malmberg, Annika B, McDonough, Stefan I
Published in PloS one (04.09.2014)
Published in PloS one (04.09.2014)
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Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity
Kim, Hye Young, PhD, Chang, Ya-Jen, PhD, Subramanian, Srividya, PhD, Lee, Hyun-Hee, PhD, Albacker, Lee A., PhD, Matangkasombut, Ponpan, MD, PhD, Savage, Paul B., PhD, McKenzie, Andrew N.J., PhD, Smith, Dirk E., MS, Rottman, James B., DVM, PhD, DeKruyff, Rosemarie H., PhD, Umetsu, Dale T., MD, PhD
Published in Journal of allergy and clinical immunology (01.01.2012)
Published in Journal of allergy and clinical immunology (01.01.2012)
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A multicenter phase 1 study of solitomab (MT110, AMG 110), a bispecific EpCAM/CD3 T-cell engager (BiTE®) antibody construct, in patients with refractory solid tumors
Kebenko, Maxim, Goebeler, Marie-Elisabeth, Wolf, Martin, Hasenburg, Annette, Seggewiss-Bernhardt, Ruth, Ritter, Barbara, Rautenberg, Beate, Atanackovic, Djordje, Kratzer, Andrea, Rottman, James B., Friedrich, Matthias, Vieser, Eva, Elm, Stefanie, Patzak, Ingrid, Wessiepe, Dorothea, Stienen, Sabine, Fiedler, Walter
Published in Oncoimmunology (01.01.2018)
Published in Oncoimmunology (01.01.2018)
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Anti-obesity effects of GIPR antagonists alone and in combination with GLP-1R agonists in preclinical models
Killion, Elizabeth A, Wang, Jinghong, Yie, Junming, Shi, Stone D-H, Bates, Darren, Min, Xiaoshan, Komorowski, Renee, Hager, Todd, Deng, Liying, Atangan, Larissa, Lu, Shu-Chen, Kurzeja, Robert J M, Sivits, Glenn, Lin, Joanne, Chen, Qing, Wang, Zhulun, Thibault, Stephen A, Abbott, Christina M, Meng, Tina, Clavette, Brandon, Murawsky, Christopher M, Foltz, Ian N, Rottman, James B, Hale, Clarence, Véniant, Murielle M, Lloyd, David J
Published in Science translational medicine (19.12.2018)
Published in Science translational medicine (19.12.2018)
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A WKB derivation for internal waves generated by a horizontally moving body in a thermocline
Broutman, Dave, Brandt, Laura, Rottman, James W., Taylor, Cecily K.
Published in Wave motion (01.09.2021)
Published in Wave motion (01.09.2021)
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Safety, Efficacy, and Biomarker Results from a Phase Ib Study of the Anti-DKK1 Antibody DKN-01 in Combination with Pembrolizumab in Advanced Esophagogastric Cancers
Klempner, Samuel J, Bendell, Johanna C, Villaflor, Victoria Meucci, Tenner, Laura LaNiel, Stein, Stacey M, Rottman, James B, Naik, Girish S, Sirard, Cynthia A, Kagey, Michael H, Chaney, Marya F, Strickler, John H
Published in Molecular cancer therapeutics (01.11.2021)
Published in Molecular cancer therapeutics (01.11.2021)
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Large scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes
Tyler, Matthew A., MD, Russell, Chris B., PhD, Smith, Dirk E., MSc, Rottman, James B., DVM, PhD, Padro Dietz, Caroline J., PhD, Hu, Xuguang, PhD, Citardi, Martin J., MD, Fakhri, Samer, MD, Assassi, Shervin, MD, Luong, Amber, MD, PhD
Published in Journal of allergy and clinical immunology (01.03.2017)
Published in Journal of allergy and clinical immunology (01.03.2017)
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Journal Article
Immunogenicity/hypersensitivity of biologics
Leach, Michael W, Rottman, James B, Hock, M Benjamin, Finco, Deborah, Rojko, Jennifer L, Beyer, Joseph C
Published in Toxicologic pathology (01.01.2014)
Published in Toxicologic pathology (01.01.2014)
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Identification of Functional Roles for Both IL-17RB and IL-17RA in Mediating IL-25-Induced Activities
Rickel, Erika A, Siegel, Lori A, Yoon, Bo-Rin Park, Rottman, James B, Kugler, David G, Swart, David A, Anders, Penny M, Tocker, Joel E, Comeau, Michael R, Budelsky, Alison L
Published in The Journal of immunology (1950) (15.09.2008)
Published in The Journal of immunology (1950) (15.09.2008)
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T-SIGn tumor reengineering therapy and CAR T cells synergize in combination therapy to clear human lung tumor xenografts and lung metastases in NSG mice
Sonzogni, Olmo, Zak, Daniel E., Sasso, Maria Stella, Lear, Rochelle, Muntzer, Alice, Zonca, Manuela, West, Katy, Champion, Brian R., Rottman, James B.
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
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Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation
Maxwell, Joseph R., Zhang, Yu, Brown, William A., Smith, Carole L., Byrne, Fergus R., Fiorino, Mike, Stevens, Erin, Bigler, Jeannette, Davis, John A., Rottman, James B., Budelsky, Alison L., Symons, Antony, Towne, Jennifer E.
Published in Immunity (Cambridge, Mass.) (20.10.2015)
Published in Immunity (Cambridge, Mass.) (20.10.2015)
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B-cell–directed CAR T-cell therapy activates CD8+ cytotoxic CARneg bystander T cells in patients and nonhuman primates
Kaminski, James, Fleming, Ryan A., Alvarez-Calderon, Francesca, Winschel, Marlana B., McGuckin, Connor, Ho, Emily E., Eng, Fay, Rui, Xianliang, Keskula, Paula, Cagnin, Lorenzo, Charles, Joanne, Zavistaski, Jillian, Margossian, Steven P., Kapadia, Malika A., Rottman, James B., Lane, Jennifer, Baumeister, Susanne H. C., Tkachev, Victor, Shalek, Alex K., Kean, Leslie S., Gerdemann, Ulrike
Published in Blood (04.07.2024)
Published in Blood (04.07.2024)
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Validation of a DKK1 RNAscope chromogenic in situ hybridization assay for gastric and gastroesophageal junction adenocarcinoma tumors
Caldwell, Charles, Rottman, James B., Paces, Will, Bueche, Elizabeth, Reitsma, Sofia, Gibb, Joseph, Adisetiyo, Vitria, Haas, Michael S., Heath, Heidi, Newman, Walter, Baum, Jason, Gianani, Roberto, Kagey, Michael H.
Published in Scientific reports (10.05.2021)
Published in Scientific reports (10.05.2021)
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IL-17RA Signaling in Airway Inflammation and Bronchial Hyperreactivity in Allergic Asthma
Willis, Cynthia R, Siegel, Lori, Leith, Anh, Mohn, Deanna, Escobar, Sabine, Wannberg, Sharon, Misura, Kira, Rickel, Erika, Rottman, James B, Comeau, Michael R, Sullivan, John K, Metz, Daniela P, Tocker, Joel, Budelsky, Alison L
Published in American journal of respiratory cell and molecular biology (01.12.2015)
Published in American journal of respiratory cell and molecular biology (01.12.2015)
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Sleeping Beauty mRNA-LNP enables stable rAAV transgene expression in mouse and NHP hepatocytes and improves vector potency
Zakas, Philip M., Cunningham, Sharon C., Doherty, Ann, van Dijk, Eva B., Ibraheim, Raed, Yu, Stephanie, Mekonnen, Befikadu D., Lang, Brendan, English, Elizabeth J., Sun, Gang, Duncan, Miles C., Benczkowski, Matthew S., Altshuler, Robert C., Singh, Malvenderjit Jagjit, Kibbler, Emily S., Tonga, Gulen Y., Wang, Zi Jun, Wang, Z. Jane, Li, Guangde, An, Ding, Rottman, James B., Bhavsar, Yashvi, Purcell, Cormac, Jain, Rachit, Alberry, Ryan, Roquet, Nathaniel, Fu, Yanfang, Citorik, Robert J., Rubens, Jacob R., Holmes, Michael C., Cotta-Ramusino, Cecilia, Querbes, William, Alexander, Ian E., Salomon, William E.
Published in Molecular therapy (02.10.2024)
Published in Molecular therapy (02.10.2024)
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IL-22 regulates iron availability in vivo through the induction of hepcidin
Smith, Carole L, Arvedson, Tara L, Cooke, Keegan S, Dickmann, Leslie J, Forte, Carla, Li, Hongyan, Merriam, Kimberly L, Perry, V Kristina, Tran, Linh, Rottman, James B, Maxwell, Joseph R
Published in The Journal of immunology (1950) (15.08.2013)
Published in The Journal of immunology (1950) (15.08.2013)
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AMG 900, a small-molecule inhibitor of aurora kinases, potentiates the activity of microtubule-targeting agents in human metastatic breast cancer models
Bush, Tammy L, Payton, Marc, Heller, Scott, Chung, Grace, Hanestad, Kelly, Rottman, James B, Loberg, Robert, Friberg, Gregory, Kendall, Richard L, Saffran, Douglas, Radinsky, Robert
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
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