Comparison of alamar blue and MTT assays for high through-put screening
Hamid, R, Rotshteyn, Y, Rabadi, L, Parikh, R, Bullock, P
Published in Toxicology in vitro (01.10.2004)
Published in Toxicology in vitro (01.10.2004)
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Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy
Valenzano, Kenneth J., Tafesse, Laykea, Lee, Gary, Harrison, James E., Boulet, Jamie M., Gottshall, Susan L., Mark, Lilly, Pearson, Michelle S., Miller, Wendy, Shan, Shen, Rabadi, Leyana, Rotshteyn, Yakov, Chaffer, Suzanne M., Turchin, Paul I., Elsemore, David A., Toth, Mathew, Koetzner, Lee, Whiteside, Garth T.
Published in Neuropharmacology (01.04.2005)
Published in Neuropharmacology (01.04.2005)
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N-(4-Tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a Novel, Orally Effective Vanilloid Receptor 1 Antagonist with Analgesic Properties: I. In Vitro Characterization and Pharmacokinetic Properties
Valenzano, Kenneth J, Grant, Elfrida R, Wu, Gang, Hachicha, Mohamed, Schmid, Lori, Tafesse, Laykea, Sun, Qun, Rotshteyn, Yakov, Francis, Joseph, Limberis, James, Malik, Shiazah, Whittemore, Edward R, Hodges, Dianne
Published in The Journal of pharmacology and experimental therapeutics (01.07.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2003)
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Journal Article
Prostate-specific membrane antigen antibody drug conjugate (PSMA ADC): A phase I trial in taxane-refractory prostate cancer
Petrylak, D. P., Kantoff, P. W., Rotshteyn, Y., Israel, R. J., Olson, W. C., Ramakrishna, T., Morris, S.
Published in Journal of clinical oncology (01.03.2011)
Published in Journal of clinical oncology (01.03.2011)
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774 SUBSTITUTION OF A CONSERVED AMINO ACID IN THE TRANSMEMBRANE DOMAIN OF E2 CONFERS RESISTANCE TO A NOVEL SMALL-MOLECULE INHIBITOR OF HCV ENTRY
Coburn, G.A, Fisch, D.N, Moorji, S, Murga, J.D, de Muys, J.-M, Paul, D, Han, A.Q, Rotshteyn, Y, Qian, D, Maddon, P.J, Olson, W.C
Published in Journal of hepatology (01.03.2011)
Published in Journal of hepatology (01.03.2011)
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112 DISCOVERY OF POTENT AND SELECTIVE INHIBITORS OF HEPATITIS C VIRUS (HCV) ENTRY WITH DISTINCT MECHANISMS OF ACTION
Coburn, G.A, Han, A.Q, Murga, J.D, de Muys, J.-M, Fisch, D.N, Paul, D, Moorji, S, Provoncha, K.P, Rotshteyn, Y, Qian, D, Maddon, P.J, Olson, W.C
Published in Journal of hepatology (2010)
Published in Journal of hepatology (2010)
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Journal Article
7 PRECLINICAL CHARACTERIZATION OF PRO 206, AN ORALLY ACTIVE SMALL-MOLECULE HEPATITIS C (HCV) ENTRY INHIBITOR
Qian, D, Coburn, G, Han, A.Q, de Muys, J.-M, Gauss, C, Provoncha, K, Canfield, M, Paul, D, Mohamed, S, Moorji, S, Fisch, D, Murga, J, Rotshteyn, Y, Maddon, P.J, Olson, W.C
Published in Journal of hepatology (2009)
Published in Journal of hepatology (2009)
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Journal Article
4-(2-Pyridyl)piperazine-1-carboxamides: Potent vanilloid receptor 1 antagonists
QUN SUN, TAFESSE, Laykea, VALENZANO, Kenneth J, KYLE, Donald J, ISLAM, Khondaker, XIAOMING ZHOU, VICTORY, Sam F, CHONGWU ZHANG, HACHICHA, Mohamed, SCHMID, Lori A, PATEL, Aniket, ROTSHTEYN, Yakov
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
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65 Targeting Ras-mutated tumors with novel multiplex PI3K inhibitors through inhibition of eIF-4E-mediated protein translation
Hamilton, M, Bernardino, A.K, Liu, Y, Provoncha, K, Paul, D, Rotshteyn, Y, Han, A, Qian, D
Published in European journal of cancer supplements (2010)
Published in European journal of cancer supplements (2010)
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Journal Article
Prostate-specific membrane antigen antibody–drug conjugate (PSMA ADC): A phase I trial in taxane-refractory prostate cancer
Petrylak, D. P., Kantoff, P. W., Frank, R. C., Shore, N. D., Rotshteyn, Y., Israel, R. J., Olson, W. C., Ramakrishna, T., Morris, S.
Published in Journal of clinical oncology (20.05.2011)
Published in Journal of clinical oncology (20.05.2011)
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Journal Article
DiPOA ([8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic Acid), a Novel, Systemically Available, and Peripherally Restricted Mu Opioid Agonist with Antihyperalgesic Activity: I. In Vitro Pharmacological Characterization and Pharmacokinetic Properties
Valenzano, Kenneth J, Miller, Wendy, Chen, Zhengming, Shan, Shen, Crumley, Gregg, Victory, Sam F, Davies, Ellen, Huang, Jin-Cheng, Allie, Nezima, Nolan, Scott J, Rotshteyn, Yakov, Kyle, Donald J, Broglé, Kevin
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
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Journal Article
DiPOA ([8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic Acid), a Novel, Systemically Available, and Peripherally Restricted Mu Opioid Agonist with Antihyperalgesic Activity: II. In Vivo Pharmacological Characterization in the Rat
Whiteside, Garth T, Harrison, James E, Pearson, Michelle S, Chen, Zhengming, Fundytus, Marian E, Rotshteyn, Yakov, Turchin, Paul I, Pomonis, James D, Mark, Lilly, Walker, Katharine, Broglé, Kevin C
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2004)
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Journal Article
Pharmacology of a new cyclic nucleotide phosphodiesterase type 4 inhibitor, V11294
Gale, Donna D, Hofer, Peter, Spina, Domenico, Seeds, Esther A, Banner, Katherine H, Harrison, Selina, Douglas, Gary, Matsumoto, Tatsui, Page, Clive P, Wong, Richard H, Jordan, Stephan, Smith, Forrest, Banik, Nandini, Halushka, Perry V, Cavalla, David, Rotshteyn, Yakov, Kyle, Donald J, Burch, Ronald M, Chasin, Mark
Published in Pulmonary pharmacology & therapeutics (01.01.2003)
Published in Pulmonary pharmacology & therapeutics (01.01.2003)
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