Synthesis, Optimization, and Large-Scale Preparation of the Low-Dose Central Nervous System-Penetrant BACE1 Inhibitor LY3202626 via a [3 + 2] Nitrone Cycloaddition
Garcia-Losada, Pablo, DeBaillie, Amy C, Eugenio de Diego, Jose, Green, Steven J, Hansen, Marvin M, Jaramillo, Carlos, Johnson, Matt, Kaoudi, Talbi, Li, Jiuyuan, Lindsay-Scott, Peter J, Mateos, Carlos, Mergott, Dustin J, Rincon, Juan Antonio, Rothhaar, Roger R, Seibert, Kevin D, Watson, Brian M, Winneroski, Leonard L, Gangula, Srinivas, Jing, Dajiang, Sun, Hao, Zhang, Lei, Frederick, Michael O
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Published in Organic process research & development (21.02.2020)
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Application of Kinetic Modeling and Competitive Solvent Hydrolysis in the Development of a Highly Selective Hydrolysis of a Nitrile to an Amide
Niemeier, Jeffry K, Rothhaar, Roger R, Vicenzi, Jeffrey T, Werner, John A
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Published in Organic process research & development (21.03.2014)
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Published in Organic process research & development (20.03.2009)
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Privileged structure-based ligands for melanocortin receptors—tetrahydroquinolines, indoles, and aminotetralines
Fisher, Matthew J., Backer, Ryan T., Husain, Saba, Hsiung, Hansen M., Mullaney, Jeffrey T., O’Brian, Thomas P., Ornstein, Paul L., Rothhaar, Roger R., Zgombick, John M., Briner, Karin
Published in Bioorganic & medicinal chemistry letters (15.10.2005)
Published in Bioorganic & medicinal chemistry letters (15.10.2005)
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Diastereo- and Enantiodifferentiation in Indium-Promoted Allylations of 2,3-Azetidinediones in Water. Definition of Long-Range Stereocontrol Elements on π-Facial Selectivity for β-Lactam Synthesis
Paquette, Leo A, Rothhaar, Roger R, Isaac, Methvin, Rogers, Lillian M, Rogers, Robin D
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Published in Journal of organic chemistry (07.08.1998)
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