Von Willebrand factor delays liver repair after acetaminophen-induced acute liver injury in mice
Groeneveld, Dafna, Cline-Fedewa, Holly, Baker, Kevin S., Williams, Kurt J., Roth, Robert A., Mittermeier, Karen, Lisman, Ton, Palumbo, Joseph S., Luyendyk, James P.
Published in Journal of hepatology (01.01.2020)
Published in Journal of hepatology (01.01.2020)
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Intrinsic versus idiosyncratic drug-induced hepatotoxicity--two villains or one?
Roth, Robert A, Ganey, Patricia E
Published in The Journal of pharmacology and experimental therapeutics (01.03.2010)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2010)
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Journal Article
Inflammatory Stress and Idiosyncratic Hepatotoxicity: Hints from Animal Models
Deng, Xiaomin, Luyendyk, James P, Ganey, Patricia E, Roth, Robert A
Published in Pharmacological reviews (01.09.2009)
Published in Pharmacological reviews (01.09.2009)
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Journal Article
Platelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice
Miyakawa, Kazuhisa, Joshi, Nikita, Sullivan, Bradley P., Albee, Ryan, Brandenberger, Christina, Jaeschke, Hartmut, McGill, Mitchell R., Scott, Michael A., Ganey, Patricia E., Luyendyk, James P., Roth, Robert A.
Published in Blood (08.10.2015)
Published in Blood (08.10.2015)
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Journal Article
Complement activation in acetaminophen-induced liver injury in mice
Singhal, Rohit, Ganey, Patricia E, Roth, Robert A
Published in The Journal of pharmacology and experimental therapeutics (01.05.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2012)
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Journal Article
Amiodarone Exposure During Modest Inflammation Induces Idiosyncrasy-like Liver Injury in Rats: Role of Tumor Necrosis Factor-alpha
Lu, Jingtao, Jones, A. Daniel, Harkema, Jack R., Roth, Robert A., Ganey, Patricia E.
Published in Toxicological Sciences (01.01.2012)
Published in Toxicological Sciences (01.01.2012)
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Metformin prevents alcohol-induced liver injury in the mouse: Critical role of plasminogen activator inhibitor-1
Bergheim, Ina, Guo, Luping, Davis, Molly Anne, Lambert, Jason C, Beier, Juliane I, Duveau, Ilinca, Luyendyk, James P, Roth, Robert A, Arteel, Gavin E
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2006)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2006)
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Journal Article
Modest Inflammation Enhances Diclofenac Hepatotoxicity in Rats: Role of Neutrophils and Bacterial Translocation
Deng, Xiaomin, Stachlewitz, Robert F, Liguori, Michael J, Blomme, Eric A G, Waring, Jeffrey F, Luyendyk, James P, Maddox, Jane F, Ganey, Patricia E, Roth, Robert A
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2006)
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Journal Article
Trovafloxacin-induced replication stress sensitizes HepG2 cells to tumor necrosis factor-alpha-induced cytotoxicity mediated by extracellular signal-regulated kinase and ataxia telangiectasia and Rad3-related
Beggs, Kevin M, Maiuri, Ashley R, Fullerton, Aaron M, Poulsen, Kyle L, Breier, Anna B, Ganey, Patricia E, Roth, Robert A
Published in Toxicology (Amsterdam) (04.05.2015)
Published in Toxicology (Amsterdam) (04.05.2015)
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Journal Article
Trovafloxacin Enhances the Inflammatory Response to a Gram-Negative or a Gram-Positive Bacterial Stimulus, Resulting in Neutrophil-Dependent Liver Injury in Mice
Shaw, Patrick J, Ganey, Patricia E, Roth, Robert A
Published in The Journal of pharmacology and experimental therapeutics (01.07.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2009)
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Journal Article
Microarray Analysis of Lipopolysaccharide Potentiation of Trovafloxacin-Induced Liver Injury in Rats Suggests a Role for Proinflammatory Chemokines and Neutrophils
Waring, Jeffrey F, Liguori, Michael J, Luyendyk, James P, Maddox, Jane F, Ganey, Patricia E, Stachlewitz, Robert F, North, Colin, Blomme, Eric A G, Roth, Robert A
Published in The Journal of pharmacology and experimental therapeutics (01.03.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2006)
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Journal Article
Coexposure of Mice to Trovafloxacin and Lipopolysaccharide, a Model of Idiosyncratic Hepatotoxicity, Results in a Unique Gene Expression Profile and Interferon Gamma–Dependent Liver Injury
Shaw, Patrick J., Ditewig, Amy C., Waring, Jeffrey F., Liguori, Michael J., Blomme, Eric A., Ganey, Patricia E., Roth, Robert A.
Published in Toxicological sciences (01.01.2009)
Published in Toxicological sciences (01.01.2009)
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Journal Article
Adverse hepatic drug reactions: inflammatory episodes as consequence and contributor
Ganey, Patricia E., Luyendyk, James P., Maddox, Jane F., Roth, Robert A.
Published in Chemico-biological interactions (01.11.2004)
Published in Chemico-biological interactions (01.11.2004)
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