Alternative modulation of protein–protein interactions by small molecules
Fischer, Gerhard, Rossmann, Maxim, Hyvönen, Marko
Published in Current opinion in biotechnology (01.12.2015)
Published in Current opinion in biotechnology (01.12.2015)
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Journal Article
Structural basis for integration of GluD receptors within synaptic organizer complexes
Elegheert, Jonathan, Kakegawa, Wataru, Clay, Jordan E., Shanks, Natalie F., Behiels, Ester, Matsuda, Keiko, Kohda, Kazuhisa, Miura, Eriko, Rossmann, Maxim, Mitakidis, Nikolaos, Motohashi, Junko, Chang, Veronica T., Siebold, Christian, Greger, Ingo H., Nakagawa, Terunaga, Yuzaki, Michisuke, Aricescu, A. Radu
Published in Science (American Association for the Advancement of Science) (15.07.2016)
Published in Science (American Association for the Advancement of Science) (15.07.2016)
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Journal Article
Double Strain-Promoted Macrocyclization for the Rapid Selection of Cell-Active Stapled Peptides
Lau, Yu Heng, Wu, Yuteng, Rossmann, Maxim, Tan, Ban Xiong, de Andrade, Peterson, Tan, Yaw Sing, Verma, Chandra, McKenzie, Grahame J., Venkitaraman, Ashok R., Hyvönen, Marko, Spring, David R.
Published in Angewandte Chemie International Edition (14.12.2015)
Published in Angewandte Chemie International Edition (14.12.2015)
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Journal Article
Dynamics and allosteric potential of the AMPA receptor N-terminal domain
Sukumaran, Madhav, Rossmann, Maxim, Shrivastava, Indira, Dutta, Anindita, Bahar, Ivet, Greger, Ingo H
Published in The EMBO journal (02.03.2011)
Published in The EMBO journal (02.03.2011)
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Journal Article
Crystal Structures of Human Saposins C and D: Implications for Lipid Recognition and Membrane Interactions
Rossmann, Maxim, Schultz-Heienbrok, Robert, Behlke, Joachim, Remmel, Natascha, Alings, Claudia, Sandhoff, Konrad, Saenger, Wolfram, Maier, Timm
Published in Structure (London) (01.05.2008)
Published in Structure (London) (01.05.2008)
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Journal Article
Intracellular calcium excess as one of the main factors in the etiology of prostate cancer
Zaichick, Vladimir, Zaichick, Sofia, Rossmann, Maxim
Published in AIMS molecular science (01.01.2016)
Published in AIMS molecular science (01.01.2016)
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Journal Article
Citrullination-dependent Differential Presentation of a Self-peptide by HLA-B27 Subtypes
Beltrami, Alessandra, Rossmann, Maxim, Fiorillo, Maria Teresa, Paladini, Fabiana, Sorrentino, Rosa, Saenger, Wolfram, Kumar, Pravin, Ziegler, Andreas, Uchanska-Ziegler, Barbara
Published in The Journal of biological chemistry (03.10.2008)
Published in The Journal of biological chemistry (03.10.2008)
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Journal Article
Functionalised staple linkages for modulating the cellular activity of stapled peptides
Lau, Yu Heng, de Andrade, Peterson, Quah, Soo-Tng, Rossmann, Maxim, Laraia, Luca, Sköld, Niklas, Sum, Tze Jing, Rowling, Pamela J. E., Joseph, Thomas L., Verma, Chandra, Hyvönen, Marko, Itzhaki, Laura S., Venkitaraman, Ashok R., Brown, Christopher J., Lane, David P., Spring, David R.
Published in Chemical science (Cambridge) (01.01.2014)
Published in Chemical science (Cambridge) (01.01.2014)
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Journal Article
Somatic genetic rescue of a germline ribosome assembly defect
Tan, Shengjiang, Kermasson, Laëtitia, Hilcenko, Christine, Kargas, Vasileios, Traynor, David, Boukerrou, Ahmed Z., Escudero-Urquijo, Norberto, Faille, Alexandre, Bertrand, Alexis, Rossmann, Maxim, Goyenechea, Beatriz, Jin, Li, Moreil, Jonathan, Alibeu, Olivier, Beaupain, Blandine, Bôle-Feysot, Christine, Fumagalli, Stefano, Kaltenbach, Sophie, Martignoles, Jean-Alain, Masson, Cécile, Nitschké, Patrick, Parisot, Mélanie, Pouliet, Aurore, Radford-Weiss, Isabelle, Tores, Frédéric, de Villartay, Jean-Pierre, Zarhrate, Mohammed, Koh, Ai Ling, Phua, Kong Boo, Reversade, Bruno, Bond, Peter J., Bellanné-Chantelot, Christine, Callebaut, Isabelle, Delhommeau, François, Donadieu, Jean, Warren, Alan J., Revy, Patrick
Published in Nature communications (19.08.2021)
Published in Nature communications (19.08.2021)
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Journal Article
Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2
Janeček, Matej, Rossmann, Maxim, Sharma, Pooja, Emery, Amy, Huggins, David J., Stockwell, Simon R., Stokes, Jamie E., Tan, Yaw S., Almeida, Estrella Guarino, Hardwick, Bryn, Narvaez, Ana J., Hyvönen, Marko, Spring, David R., McKenzie, Grahame J., Venkitaraman, Ashok R.
Published in Scientific reports (24.06.2016)
Published in Scientific reports (24.06.2016)
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Journal Article
Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents
Stockwell, Simon R, Scott, Duncan E, Fischer, Gerhard, Guarino, Estrella, Rooney, Timothy P C, Feng, Tzu-Shean, Moschetti, Tommaso, Srinivasan, Rajavel, Alza, Esther, Asteian, Alice, Dagostin, Claudio, Alcaide, Anna, Rocaboy, Mathieu, Blaszczyk, Beata, Higueruelo, Alicia, Wang, Xuelu, Rossmann, Maxim, Perrior, Trevor R, Blundell, Tom L, Spring, David R, McKenzie, Grahame, Abell, Chris, Skidmore, John, Venkitaraman, Ashok R, Hyvönen, Marko
Published in Journal of medicinal chemistry (12.09.2024)
Published in Journal of medicinal chemistry (12.09.2024)
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Journal Article
Second-generation CK2 alpha inhibitors targeting the alpha D pocket
Iegre, Jessica, Brear, Paul, De Fusco, Claudia, Yoshida, Masao, Mitchell, Sophie L., Rossmann, Maxim, Carro, Laura, Sore, Hannah F., Hyvonen, Marko, Spring, David R.
Published in Chemical science (Cambridge) (21.03.2018)
Published in Chemical science (Cambridge) (21.03.2018)
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Journal Article
Development of a multipurpose scaffold for the display of peptide loops
Rossmann, Maxim, J. Greive, Sandra, Moschetti, Tommaso, Dinan, Michael, Hyvönen, Marko
Published in Protein engineering, design and selection (01.06.2017)
Published in Protein engineering, design and selection (01.06.2017)
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Journal Article
A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation
Sharma, Pooja, Mahen, Robert, Rossmann, Maxim, Stokes, Jamie E., Hardwick, Bryn, Huggins, David J., Emery, Amy, Kunciw, Dominique L., Hyvönen, Marko, Spring, David R., McKenzie, Grahame J., Venkitaraman, Ashok R.
Published in Scientific reports (04.11.2019)
Published in Scientific reports (04.11.2019)
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Journal Article
Computationally-guided optimization of small-molecule inhibitors of the Aurora A kinase-TPX2 protein-protein interaction
Cole, Daniel J, Janecek, Matej, Stokes, Jamie E, Rossmann, Maxim, Faver, John C, McKenzie, Grahame J, Venkitaraman, Ashok R, Hyvönen, Marko, Spring, David R, Huggins, David J, Jorgensen, William L
Published in Chemical communications (Cambridge, England) (17.08.2017)
Published in Chemical communications (Cambridge, England) (17.08.2017)
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Journal Article
Development of a Multifunctional Benzophenone Linker for Peptide Stapling and Photoaffinity Labelling
Wu, Yuteng, Olsen, Lasse B., Lau, Yu Heng, Jensen, Claus Hatt, Rossmann, Maxim, Baker, Ysobel R., Sore, Hannah F., Collins, Súil, Spring, David R.
Published in Chembiochem : a European journal of chemical biology (15.04.2016)
Published in Chembiochem : a European journal of chemical biology (15.04.2016)
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Journal Article
Publisher Correction: Somatic genetic rescue of a germline ribosome assembly defect
Tan, Shengjiang, Kermasson, Laëtitia, Hilcenko, Christine, Kargas, Vasileios, Traynor, David, Boukerrou, Ahmed Z., Escudero-Urquijo, Norberto, Faille, Alexandre, Bertrand, Alexis, Rossmann, Maxim, Goyenechea, Beatriz, Jin, Li, Moreil, Jonathan, Alibeu, Olivier, Beaupain, Blandine, Bôle-Feysot, Christine, Fumagalli, Stefano, Kaltenbach, Sophie, Martignoles, Jean-Alain, Masson, Cécile, Nitschké, Patrick, Parisot, Mélanie, Pouliet, Aurore, Radford-Weiss, Isabelle, Tores, Frédéric, de Villartay, Jean-Pierre, Zarhrate, Mohammed, Koh, Ai Ling, Phua, Kong Boo, Reversade, Bruno, Bond, Peter J., Bellanné-Chantelot, Christine, Callebaut, Isabelle, Delhommeau, François, Donadieu, Jean, Warren, Alan J., Revy, Patrick
Published in Nature communications (22.06.2022)
Published in Nature communications (22.06.2022)
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Journal Article
Second-generation CK2α inhibitors targeting the αD pocketElectronic supplementary information (ESI) available: All experimental details, crystallographic data collection and refinement statistics, details of chemical synthesis, additional figures and tables. See DOI: 10.1039/c7sc05122k
Iegre, Jessica, Brear, Paul, De Fusco, Claudia, Yoshida, Masao, Mitchell, Sophie L, Rossmann, Maxim, Carro, Laura, Sore, Hannah F, Hyvönen, Marko, Spring, David R
Year of Publication 14.03.2018
Year of Publication 14.03.2018
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Journal Article
Second-generation CK2α inhibitors targeting the αD pocket† †Electronic supplementary information (ESI) available: All experimental details, crystallographic data collection and refinement statistics, details of chemical synthesis, additional figures and tables. See DOI: 10.1039/c7sc05122k
Iegre, Jessica, Brear, Paul, De Fusco, Claudia, Yoshida, Masao, Mitchell, Sophie L., Rossmann, Maxim, Carro, Laura, Sore, Hannah F., Hyvönen, Marko, Spring, David R.
Published in Chemical science (Cambridge) (20.02.2018)
Published in Chemical science (Cambridge) (20.02.2018)
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Journal Article