Sacituzumab Govitecan (IMMU-132), an Anti-Trop-2/SN-38 Antibody–Drug Conjugate: Characterization and Efficacy in Pancreatic, Gastric, and Other Cancers
Cardillo, Thomas M., Govindan, Serengulam V., Sharkey, Robert M., Trisal, Preeti, Arrojo, Roberto, Liu, Donglin, Rossi, Edmund A., Chang, Chien-Hsing, Goldenberg, David M.
Published in Bioconjugate chemistry (20.05.2015)
Published in Bioconjugate chemistry (20.05.2015)
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Journal Article
Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody
Goldenberg, David M., Rossi, Edmund A., Stein, Rhona, Cardillo, Thomas M., Czuczman, Myron S., Hernandez-Ilizaliturri, Francisco J., Hansen, Hans J., Chang, Chien-Hsing
Published in Blood (29.01.2009)
Published in Blood (29.01.2009)
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Journal Article
Stably Tethered Multifunctional Structures of Defined Composition Made by the Dock and Lock Method for Use in Cancer Targeting
Rossi, Edmund A., Goldenberg, David M., Cardillo, Thomas M., McBride, William J., Sharkey, Robert M., Chang, Chien-Hsing
Published in Proceedings of the National Academy of Sciences - PNAS (02.05.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (02.05.2006)
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Journal Article
Recombinant Bispecific Monoclonal Antibodies Prepared by the Dock-and-Lock Strategy for Pretargeted Radioimmunotherapy
Sharkey, Robert M., PhD, Rossi, Edmund A., PhD, McBride, William J., PhD, Chang, Chien-Hsing, PhD, Goldenberg, David M., ScD, MD
Published in Seminars in nuclear medicine (01.05.2010)
Published in Seminars in nuclear medicine (01.05.2010)
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Journal Article
The Dock and Lock Method: A Novel Platform Technology for Building Multivalent, Multifunctional Structures of Defined Composition with Retained Bioactivity
CHANG, Chien-Hsing, ROSSI, Edmund A, GOLDENBERG, David M
Published in Clinical cancer research (15.09.2007)
Published in Clinical cancer research (15.09.2007)
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Journal Article
Conference Proceeding
Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody
Goldenberg, David M, Sharkey, Robert M, Cardillo, Thomas M, Rossi, Edmund A, Chang, Chien-Hsing, Karacay, Habibe, McBride, William J, Hansen, Hans J, Horak, Ivan D
Published in Nature medicine (01.11.2005)
Published in Nature medicine (01.11.2005)
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Journal Article
A novel bispecific, trivalent antibody construct for targeting pancreatic carcinoma
Gold, David V, Goldenberg, David M, Karacay, Habibe, Rossi, Edmund A, Chang, Chien-Hsing, Cardillo, Thomas M, McBride, William J, Sharkey, Robert M
Published in Cancer research (Chicago, Ill.) (15.06.2008)
Published in Cancer research (Chicago, Ill.) (15.06.2008)
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Journal Article
Improving the Delivery of Radionuclides for Imaging and Therapy of Cancer Using Pretargeting Methods
SHARKEY, Robert M, KARACAY, Habibe, CARDILLO, Thomas M, CHANG, Chien-Hsing, MCBRIDE, William J, ROSSI, Edmund A, HORAK, Ivan D, GOLDENBERG, David M
Published in Clinical cancer research (01.10.2005)
Published in Clinical cancer research (01.10.2005)
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Journal Article
Conference Proceeding
A novel class of anti-HIV agents with multiple copies of enfuvirtide enhances inhibition of viral replication and cellular transmission in vitro
Chang, Chien-Hsing, Hinkula, Jorma, Loo, Meiyu, Falkeborn, Tina, Li, Rongxiu, Cardillo, Thomas M, Rossi, Edmund A, Goldenberg, David M, Wahren, Britta
Published in PloS one (23.07.2012)
Published in PloS one (23.07.2012)
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Journal Article
Evaluation of a novel hexavalent humanized anti-IGF-1R antibody and its bivalent parental IgG in diverse cancer cell lines
Chang, Chien-Hsing, Wang, Yang, Trisal, Preeti, Li, Rongxiu, Rossi, Diane L, Nair, Anju, Gupta, Pankaj, Losman, Michele, Cardillo, Thomas M, Rossi, Edmund A, Goldenberg, David M
Published in PloS one (31.08.2012)
Published in PloS one (31.08.2012)
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Journal Article
Bispecific Antibody Pretargeting of Radionuclides for Immuno–Single-Photon Emission Computed Tomography and Immuno–Positron Emission Tomography Molecular Imaging: An Update
SHARKEY, Robert M, KARACAY, Habibe, MCBRIDE, William J, ROSSI, Edmund A, CHANG, Chien-Hsing, GOLDENBERG, David M
Published in Clinical cancer research (15.09.2007)
Published in Clinical cancer research (15.09.2007)
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Journal Article
Conference Proceeding
Combination Therapy with Bispecific Antibodies and PD-1 Blockade Enhances the Antitumor Potency of T Cells
Chang, Chien-Hsing, Wang, Yang, Li, Rongxiu, Rossi, Diane L, Liu, Donglin, Rossi, Edmund A, Cardillo, Thomas M, Goldenberg, David M
Published in Cancer research (Chicago, Ill.) (01.10.2017)
Published in Cancer research (Chicago, Ill.) (01.10.2017)
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Journal Article
Enhanced Delivery of SN-38 to Human Tumor Xenografts with an Anti-Trop-2-SN-38 Antibody Conjugate (Sacituzumab Govitecan)
Sharkey, Robert M, McBride, William J, Cardillo, Thomas M, Govindan, Serengulam V, Wang, Yang, Rossi, Edmund A, Chang, Chien-Hsing, Goldenberg, David M
Published in Clinical cancer research (15.11.2015)
Published in Clinical cancer research (15.11.2015)
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Journal Article
Therapeutic Advantage of Pretargeted Radioimmunotherapy Using a Recombinant Bispecific Antibody in a Human Colon Cancer Xenograft
KARACAY, Habibe, BRARD, Pierre-Yves, SHARKEY, Robert M, CHANG, Chien-Hsing, ROSSI, Edmund A, MCBRIDE, William J, RAGLAND, Dan R, HORAK, Ivan D, GOLDENBERG, David M
Published in Clinical cancer research (01.11.2005)
Published in Clinical cancer research (01.11.2005)
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