Role of cytochrome P450 2B sequence variation and gene copy number in facilitating dietary specialization in mammalian herbivores
Kitanovic, Smiljka, Orr, Teri J., Spalink, Daniel, Cocke, Granger B., Schramm, Katharina, Wilderman, P. Ross, Halpert, James R., Dearing, M. Denise
Published in Molecular ecology (01.02.2018)
Published in Molecular ecology (01.02.2018)
Get full text
Journal Article
Tyrosine Nitration Contributes to Nitric Oxide-Stimulated Degradation of CYP2B6
Lee, Choon-Myung, Wilderman, P Ross, Park, Ji Won, Murphy, Thomas J, Morgan, Edward T
Published in Molecular pharmacology (01.09.2020)
Published in Molecular pharmacology (01.09.2020)
Get full text
Journal Article
Strategies in herbivory by mammals revisited: The role of liver metabolism in a juniper specialist (Neotoma stephensi) and a generalist (Neotoma albigula)
Orr, Teri J., Kitanovic, Smiljka, Schramm, Katharina M., Skopec, Michele M., Wilderman, P. Ross, Halpert, James R., Dearing, M. Denise
Published in Molecular ecology (01.05.2020)
Published in Molecular ecology (01.05.2020)
Get full text
Journal Article
Conformational Adaptation of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 Revealed upon Binding Multiple Amlodipine Molecules
Shah, Manish B, Wilderman, P. Ross, Pascual, Jaime, Zhang, Qinghai, Stout, C. David, Halpert, James R
Published in Biochemistry (Easton) (18.09.2012)
Published in Biochemistry (Easton) (18.09.2012)
Get full text
Journal Article
Functional characterization of the rice kaurene synthase-like gene family
Xu, Meimei, Ross Wilderman, P., Morrone, Dana, Xu, Jianjun, Roy, Arnab, Margis-Pinheiro, Marcia, Upadhyaya, Narayana M., Coates, Robert M., Peters, Reuben J.
Published in Phytochemistry (Oxford) (01.02.2007)
Published in Phytochemistry (Oxford) (01.02.2007)
Get full text
Journal Article
Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism
Shah, Manish B, Liu, Jingbao, Huo, Lu, Zhang, Qinghai, Dearing, M Denise, Wilderman, P Ross, Szklarz, Grazyna D, Stout, C David, Halpert, James R
Published in Molecular pharmacology (01.04.2016)
Published in Molecular pharmacology (01.04.2016)
Get full text
Journal Article
Investigation by site‐directed mutagenesis of the role of cytochrome P450 2B4 non‐active‐site residues in protein–ligand interactions based on crystal structures of the ligand‐bound enzyme
Wilderman, P. Ross, Gay, Sean C., Jang, Hyun‐Hee, Zhang, Qinghai, Stout, C. David, Halpert, James R.
Published in The FEBS journal (01.05.2012)
Published in The FEBS journal (01.05.2012)
Get full text
Journal Article
16-Aza-ent-beyerane and 16-Aza-ent-trachylobane: Potent Mechanism-Based Inhibitors of Recombinant ent-Kaurene Synthase from Arabidopsis thaliana
Roy, Arnab, Roberts, Frank G, Wilderman, P. Ross, Zhou, Ke, Peters, Reuben J, Coates, Robert M
Published in Journal of the American Chemical Society (17.10.2007)
Published in Journal of the American Chemical Society (17.10.2007)
Get full text
Journal Article
A Modular Approach for Facile Biosynthesis of Labdane-Related Diterpenes
Cyr, Anthony, Wilderman, P. Ross, Determan, Mara, Peters, Reuben J
Published in Journal of the American Chemical Society (30.05.2007)
Published in Journal of the American Chemical Society (30.05.2007)
Get full text
Journal Article
A Single Residue Switch Converts Abietadiene Synthase into a Pimaradiene Specific Cyclase
Wilderman, P. Ross, Peters, Reuben J
Published in Journal of the American Chemical Society (26.12.2007)
Published in Journal of the American Chemical Society (26.12.2007)
Get full text
Journal Article
Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7‑Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations
Liu, Jingbao, Shah, Manish B, Zhang, Qinghai, Stout, C. David, Halpert, James R, Wilderman, P. Ross
Published in Biochemistry (Easton) (05.04.2016)
Published in Biochemistry (Easton) (05.04.2016)
Get full text
Journal Article
Rational Re-Engineering of the O‑Dealkylation of 7‑Alkoxycoumarin Derivatives by Cytochromes P450 2B from the Desert Woodrat Neotoma lepida
Huo, Lu, Liu, Jingbao, Dearing, M. Denise, Szklarz, Grazyna D, Halpert, James R, Wilderman, P. Ross
Published in Biochemistry (Easton) (25.04.2017)
Published in Biochemistry (Easton) (25.04.2017)
Get full text
Journal Article