Intrinsic Allosteric Inhibition of Signaling Proteins by Targeting Rare Interaction States Detected by High-Pressure NMR Spectroscopy
Kalbitzer, Hans Robert, Rosnizeck, Ina C., Munte, Claudia E., Narayanan, Sunilkumar Puthenpurackal, Kropf, Veronika, Spoerner, Michael
Published in Angewandte Chemie (International ed.) (23.12.2013)
Published in Angewandte Chemie (International ed.) (23.12.2013)
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Journal Article
Stabilizing a Weak Binding State for Effectors in the Human Ras Protein by Cyclen Complexes
Rosnizeck, Ina C, Graf, Thorsten, Spoerner, Michael, Tränkle, Jens, Filchtinski, Daniel, Herrmann, Christian, Gremer, Lothar, Vetter, Ingrid R, Wittinghofer, Alfred, König, Burkhard, Kalbitzer, Hans Robert
Published in Angewandte Chemie (International ed.) (17.05.2010)
Published in Angewandte Chemie (International ed.) (17.05.2010)
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Journal Article
Metal-Bis(2-picolyl)amine Complexes as State 1(T) Inhibitors of Activated Ras Protein
Rosnizeck, Ina C., Spoerner, Michael, Harsch, Tobias, Kreitner, Sandra, Filchtinski, Daniel, Herrmann, Christian, Engel, Daniel, König, Burkhard, Kalbitzer, Hans Robert
Published in Angewandte Chemie (International ed.) (15.10.2012)
Published in Angewandte Chemie (International ed.) (15.10.2012)
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Journal Article
Cu2+-cyclen as Probe to Identify Conformational States in Guanine Nucleotide Binding Proteins
Meierhofer, Tanja, Rosnizeck, Ina C, Graf, Thorsten, Reiss, Kerstin, König, Burkhard, Kalbitzer, Hans Robert, Spoerner, Michael
Published in Journal of the American Chemical Society (23.02.2011)
Published in Journal of the American Chemical Society (23.02.2011)
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Journal Article
Time-Resolved Fluorescence-Based Assay for the Determination of Alkaline Phosphatase Activity and Application to the Screening of Its Inhibitors
Schrenkhammer, Petra, Rosnizeck, Ina C., Duerkop, Axel, Wolfbeis, Otto S., Schäferling, Michael
Published in Journal of biomolecular screening (01.01.2008)
Published in Journal of biomolecular screening (01.01.2008)
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Intrinsische allosterische Hemmung von Signalproteinen durch Stabilisierung gering besetzter, durch Hochdruck-NMR-Spektroskopie nachweisbarer Interaktionszustände
Kalbitzer, Hans Robert, Rosnizeck, Ina C., Munte, Claudia E., Narayanan, Sunilkumar Puthenpurackal, Kropf, Veronika, Spoerner, Michael
Published in Angewandte Chemie (23.12.2013)
Published in Angewandte Chemie (23.12.2013)
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Journal Article
Metall-Bis(2-picolyl)amin-Komplexe als Zustand-1(T)-Inhibitoren für aktiviertes Ras-Protein
Rosnizeck, Ina C., Spoerner, Michael, Harsch, Tobias, Kreitner, Sandra, Filchtinski, Daniel, Herrmann, Christian, Engel, Daniel, König, Burkhard, Kalbitzer, Hans Robert
Published in Angewandte Chemie (15.10.2012)
Published in Angewandte Chemie (15.10.2012)
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Journal Article
Cu 2+ -cyclen as Probe to Identify Conformational States in Guanine Nucleotide Binding Proteins
Meierhofer, Tanja, Rosnizeck, Ina C., Graf, Thorsten, Reiss, Kerstin, König, Burkhard, Kalbitzer, Hans Robert, Spoerner, Michael
Published in Journal of the American Chemical Society (23.02.2011)
Published in Journal of the American Chemical Society (23.02.2011)
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Journal Article
Metal-Bis(2-picolyl)amine Complexes as State1(T) Inhibitors of Activated Ras Protein
Rosnizeck, Ina C, Spoerner, Michael, Harsch, Tobias, Kreitner, Sandra, Filchtinski, Daniel, Herrmann, Christian, Engel, Daniel, Konig, Burkhard, Kalbitzer, Hans Robert
Published in Angewandte Chemie International Edition (01.10.2012)
Published in Angewandte Chemie International Edition (01.10.2012)
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Journal Article
Intrinsische allosterische Hemmung von Signalproteinen durch Stabilisierung gering besetzter, durch Hochdruck‐NMR‐Spektroskopie nachweisbarer Interaktionszustände
Kalbitzer, Hans Robert, Rosnizeck, Ina C., Munte, Claudia E., Narayanan, Sunilkumar Puthenpurackal, Kropf, Veronika, Spoerner, Michael
Published in Angewandte Chemie (23.12.2013)
Published in Angewandte Chemie (23.12.2013)
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Journal Article
Metall‐Bis(2‐picolyl)amin‐Komplexe als Zustand‐1(T)‐Inhibitoren für aktiviertes Ras‐Protein
Rosnizeck, Ina C., Spoerner, Michael, Harsch, Tobias, Kreitner, Sandra, Filchtinski, Daniel, Herrmann, Christian, Engel, Daniel, König, Burkhard, Kalbitzer, Hans Robert
Published in Angewandte Chemie (15.10.2012)
Published in Angewandte Chemie (15.10.2012)
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Journal Article
Stabilisierung eines niederaffinen Zustands für Effektoren im menschlichen Ras-Protein durch Cyclenkomplexe
Rosnizeck, Ina C., Graf, Thorsten, Spoerner, Michael, Tränkle, Jens, Filchtinski, Daniel, Herrmann, Christian, Gremer, Lothar, Vetter, Ingrid R., Wittinghofer, Alfred, König, Burkhard, Kalbitzer, Hans Robert
Published in Angewandte Chemie (17.05.2010)
Published in Angewandte Chemie (17.05.2010)
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Journal Article
Elucidating the Mode of Action of a Typical Ras State 1(T) Inhibitor
Rosnizeck, Ina C, Filchtinski DanielauthorRuhr-University of Bochum, Institute of Physical Chemistry I, Universitatsstrae 150, 44780 Bochum, Germany, Lopes Rui PedroauthorUniversity of Regensburg, Institute of Biophysics and Physical Biochemistry, Centre of Magnetic Resonance in Chemistry and Biomedicine, Universitatsstrae 31, 93053 Regensburg, Germany, Kieninger BarbelauthorUniversity of Regensburg, Institute of Biophysics and Physical Biochemistry, Centre of Magnetic Resonance in Chemistry and Biomedicine, Universitatsstrae 31, 93053 Regensburg, Germany, Herrmann ChristianauthorRuhr-University of Bochum, Institute of Physical Chemistry I, Universitatsstrae 150, 44780 Bochum, Germany, Kalbitzer Hans RobertauthorUniversity of Regensburg, Institute of Biophysics and Physical Biochemistry, Centre of Magnetic Resonance in Chemistry and Biomedicine, Universitatsstrae 31, 93053 Regensburg, Germany, Spoerner MichaelauthorUniversity of Regensburg, Institute of Biophysics and Physical Biochemistry, Centre of Magnetic Resonance in Chemistry and Biomedicine, Universitatsstrae 31, 93053 Regensburg, Germany
Year of Publication 2015
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Year of Publication 2015
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