Bypassing Drug Resistance Mechanisms of Prostate Cancer with Small Molecules that Target Androgen Receptor-Chromatin Interactions
Dalal, Kush, Che, Meixia, Que, Nanette S, Sharma, Aishwariya, Yang, Rendong, Lallous, Nada, Borgmann, Hendrik, Ozistanbullu, Deniz, Tse, Ronnie, Ban, Fuqiang, Li, Huifang, Tam, Kevin J, Roshan-Moniri, Mani, LeBlanc, Eric, Gleave, Martin E, Gewirth, Daniel T, Dehm, Scott M, Cherkasov, Artem, Rennie, Paul S
Published in Molecular cancer therapeutics (01.10.2017)
Published in Molecular cancer therapeutics (01.10.2017)
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Journal Article
Orphan nuclear receptors as drug targets for the treatment of prostate and breast cancers
Roshan-Moniri, Mani, Hsing, Michael, Butler, Miriam S, Cherkasov, Artem, Rennie, Paul S
Published in Cancer treatment reviews (01.12.2014)
Published in Cancer treatment reviews (01.12.2014)
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Journal Article
Transcriptome-Based Analysis of Molecular Pathways for Clusterin Functions in Kidney Cells
Dairi, Ghida, Guan, Qiunong, Roshan-Moniri, Mani, Collins, Colin C., Ong, Christopher J., Gleave, Martin E., Nguan, Christopher Y.C., Du, Caigan
Published in Journal of cellular physiology (01.12.2016)
Published in Journal of cellular physiology (01.12.2016)
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Journal Article
Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer
Butler, Miriam S, Roshan-Moniri, Mani, Hsing, Michael, Lau, Desmond, Kim, Ari, Yen, Paul, Mroczek, Marta, Nouri, Mannan, Lien, Scott, Axerio-Cilies, Peter, Dalal, Kush, Yau, Clement, Ghaidi, Fariba, Guo, Yubin, Yamazaki, Takeshi, Lawn, Sam, Gleave, Martin E, Gregory-Evans, Cheryl Y, McIntosh, Lawrence P, Cox, Michael E, Rennie, Paul S, Cherkasov, Artem
Published in Oncotarget (27.06.2017)
Published in Oncotarget (27.06.2017)
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Journal Article
Selectively Targeting the DNA-binding Domain of the Androgen Receptor as a Prospective Therapy for Prostate Cancer
Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hessein, Mohamed, Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma S., Cherkasov, Artem, Rennie, Paul S.
Published in The Journal of biological chemistry (19.09.2014)
Published in The Journal of biological chemistry (19.09.2014)
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Journal Article
Selectively targeting the dimerization interface of human androgen receptor with small-molecules to treat castration-resistant prostate cancer
Dalal, Kush, Ban, Fuqiang, Li, Huifang, Morin, Hélène, Roshan-Moniri, Mani, Tam, Kevin J., Shepherd, Ashley, Sharma, Aishwariya, Peacock, James, Carlson, Michael L., LeBlanc, Eric, Perez, Carl, Duong, Franck, Ong, Christopher J., Rennie, Paul S., Cherkasov, Artem
Published in Cancer letters (28.11.2018)
Published in Cancer letters (28.11.2018)
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Journal Article
Angiopoietin-like 4 Enhances the Proliferation and Migration of Tendon Fibroblasts
Jamil, Sarwat, Mousavizadeh, Rouhollah, Roshan-Moniri, Mani, Tebbutt, Scott J, McCormack, Robert G, Duronio, Vincent, Scott, Alex
Published in Medicine and science in sports and exercise (01.09.2017)
Published in Medicine and science in sports and exercise (01.09.2017)
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Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment
Hosseini-Beheshti, Elham, Choi, Wendy, Weiswald, Louis-Bastien, Kharmate, Geetanjali, Ghaffari, Mazyar, Roshan-Moniri, Mani, Hassona, Mohamed D, Chan, Leslie, Chin, Mei Yieng, Tai, Isabella T, Rennie, Paul S, Fazli, Ladan, Tomlinson Guns, Emma S
Published in Oncotarget (22.03.2016)
Published in Oncotarget (22.03.2016)
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Journal Article
Therapy-induced developmental reprogramming of prostate cancer cells and acquired therapy resistance
Nouri, Mannan, Caradec, Josselin, Lubik, Amy Anne, Li, Na, Hollier, Brett G, Takhar, Mandeep, Altimirano-Dimas, Manuel, Chen, Mengqian, Roshan-Moniri, Mani, Butler, Miriam, Lehman, Melanie, Bishop, Jennifer, Truong, Sarah, Huang, Shih-Chieh, Cochrane, Dawn, Cox, Michael, Collins, Colin, Gleave, Martin, Erho, Nicholas, Alshalafa, Mohamed, Davicioni, Elai, Nelson, Colleen, Gregory-Evans, Sheryl, Karnes, R Jeffrey, Jenkins, Robert B, Klein, Eric A, Buttyan, Ralph
Published in Oncotarget (21.03.2017)
Published in Oncotarget (21.03.2017)
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Journal Article
Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation
Lallous, Nada, Leblanc, Eric, Munuganti, Ravi S N, Hassona, Mohamed D H, Nakouzi, Nader Al, Awrey, Shannon, Morin, Helene, Roshan-Moniri, Mani, Singh, Kriti, Lawn, Sam, Yamazaki, Takeshi, Adomat, Hans H, Andre, Christophe, Daugaard, Mads, Young, Robert N, Guns, Emma S Tomlinson, Rennie, Paul S, Cherkasov, Artem
Published in Molecular cancer therapeutics (01.12.2016)
Published in Molecular cancer therapeutics (01.12.2016)
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Journal Article
Abstract 4644: Inhibition of the androgen receptor at two drug-targetable sites on the DNA-binding domain protein surface
Dalal, Kush, Sharma, Aishwariya, Roshan-Moniri, Mani, Borgmann, Hendrik, Lallous, Nada, Awrey, Shannon, Li, Huifang, Ban, Fuqiang, LeBlanc, Eric, Cherkasov, Artem, Rennie, Paul S.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer
Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hassona, Mohamed D., Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma S., Cherkasov, Artem, Rennie, Paul S.
Published in The Journal of biological chemistry (10.03.2017)
Published in The Journal of biological chemistry (10.03.2017)
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Journal Article
Abstract 4908: Neuropilin-1 is up-regulated in the adaptive response of prostate tumors to androgen targeted therapies and is prognostic of metastatic progression and patient mortality
Volpert, Marianna, Tse, Brian, Ratther, Ellca, Stylianou, Nataly, Nouri, Mannan, Lehman, Melanie, McPherson, Stephen, Roshan-Moniri, Mani, Takhar, Mandeep, Erho, Nicholas, Alshalafa, Mohamed, Davicioni, Elai, Jenkins, Robert, Ross, Ashley, Karnes, Jeffrey, Den, Robert, Fazli, Ladan, Gleave, Martin, Williams, Elizabeth, Rennie, Paul, Buttyan, Ralph, Russell, Pamela, Nelson, Colleen, Hollier, Brett
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 130: Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer
Butler, Miriam S., Roshan-Moniri, Mani, Hsing, Michael, Lau, Desmond, Kim, Ari, Yen, Paul, Mroczek, Marta, Nouri, Mannan, Lien, Scott, Axerio-Cilies, Peter, Dalal, Kush, Yau, Clement, Ghaidi, Fariba, Guo, Yubin, Yamazaki, Takeshi, Lawn, Sam, Gleave, Martin, Gregory-Evans, Cheryl Y., McIntosh, Lawrence P., Rennie, Paul S., Cherkasov, Artem, Cox, Michael E.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Use it or lose it? Sablefish, Anoplopoma fimbria , a species representing a fifth teleostean group where the βNHE associated with the red blood cell adrenergic stress response has been secondarily lost
Rummer, Jodie L., Roshan-Moniri, Mani, Balfry, Shannon K., Brauner, Colin J.
Published in Journal of experimental biology (01.05.2010)
Published in Journal of experimental biology (01.05.2010)
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Journal Article
The future of prostate cancer precision medicine: anti-ERG therapies
Roshan-Moniri, Mani, Hsing, Michael, Rennie, Paul S., Cherkasov, Artem, Cox, Michael E.
Published in Translational cancer research (01.10.2017)
Published in Translational cancer research (01.10.2017)
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Journal Article
Abstract 1648: Targeting ETS factor ETV4 as a novel therapeutic for the management of breast and prostate cancer
Butler, Miriam S., Hsing, Michael, Roshan Moniri, Mani, Lau, Desmond, Yen, Paul, Kim, Ari, Lien, Scott, Mroczek, Marta, Ghaidi, Fariba, LeBlanc, Eric, McIntosh, Lawrence, Cox, Michael, Cherkasov, Artem, Rennie, Paul S.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 1778: Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer
Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hassona, Mohamed D., Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma, Cherkasov, Artem, Rennie, Paul S.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer
Dalal, Kush, Roshan-Moniri, Mani, Sharma, Aishwariya, Li, Huifang, Ban, Fuqiang, Hessein, Mohamed, Hsing, Michael, Singh, Kriti, LeBlanc, Eric, Dehm, Scott, Tomlinson Guns, Emma S., Cherkasov, Artem, Rennie, Paul S.
Published in The Journal of biological chemistry (05.12.2014)
Published in The Journal of biological chemistry (05.12.2014)
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