Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress
Kaymak, Irem, Maier, Carina R, Schmitz, Werner, Campbell, Andrew D, Dankworth, Beatrice, Ade, Carsten P, Walz, Susanne, Paauwe, Madelon, Kalogirou, Charis, Marouf, Hecham, Rosenfeldt, Mathias T, Gay, David M, McGregor, Grace H, Sansom, Owen J, Schulze, Almut
Published in Cancer research (Chicago, Ill.) (15.01.2020)
Published in Cancer research (Chicago, Ill.) (15.01.2020)
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Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1
Laine, Anni, Sihto, Harri, Come, Christophe, Rosenfeldt, Mathias T, Zwolinska, Aleksandra, Niemelä, Minna, Khanna, Anchit, Chan, Edward K, Kähäri, Veli-Matti, Kellokumpu-Lehtinen, Pirkko-Liisa, Sansom, Owen J, Evan, Gerard I, Junttila, Melissa R, Ryan, Kevin M, Marine, Jean-Christophe, Joensuu, Heikki, Westermarck, Jukka
Published in Cancer discovery (01.02.2013)
Published in Cancer discovery (01.02.2013)
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Analysis of macroautophagy by immunohistochemistry
Rosenfeldt, Mathias T, Nixon, Colin, Liu, Emma, Mah, Li Yen, Ryan, Kevin M
Published in Autophagy (01.06.2012)
Published in Autophagy (01.06.2012)
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Journal Article
RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells
Otto, Christoph, Kastner, Carolin, Schmidt, Stefanie, Uttinger, Konstantin, Baluapuri, Apoorva, Denk, Sarah, Rosenfeldt, Mathias T., Rosenwald, Andreas, Roehrig, Florian, Ade, Carsten P., Schuelein‐Voelk, Christina, Diefenbacher, Markus E., Germer, Christoph‐Thomas, Wolf, Elmar, Eilers, Martin, Wiegering, Armin
Published in Molecular oncology (01.08.2022)
Published in Molecular oncology (01.08.2022)
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Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease
Hartmann, Oliver, Reissland, Michaela, Maier, Carina R, Fischer, Thomas, Prieto-Garcia, Cristian, Baluapuri, Apoorva, Schwarz, Jessica, Schmitz, Werner, Garrido-Rodriguez, Martin, Pahor, Nikolett, Davies, Clare C, Bassermann, Florian, Orian, Amir, Wolf, Elmar, Schulze, Almut, Calzado, Marco A, Rosenfeldt, Mathias T, Diefenbacher, Markus E
Published in Frontiers in cell and developmental biology (02.03.2021)
Published in Frontiers in cell and developmental biology (02.03.2021)
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Autophagy Blockage Reduces the Incidence of Pancreatic Ductal Adenocarcinoma in the Context of Mutant Trp53
Mainz, Laura, Sarhan, Mohamed A F E, Roth, Sabine, Sauer, Ursula, Maurus, Katja, Hartmann, Elena M, Seibert, Helen-Desiree, Rosenwald, Andreas, Diefenbacher, Markus E, Rosenfeldt, Mathias T
Published in Frontiers in cell and developmental biology (16.03.2022)
Published in Frontiers in cell and developmental biology (16.03.2022)
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Journal Article
p53 status determines the role of autophagy in pancreatic tumour development
Rosenfeldt, Mathias T., O’Prey, Jim, Morton, Jennifer P., Nixon, Colin, MacKay, Gillian, Mrowinska, Agata, Au, Amy, Rai, Taranjit Singh, Zheng, Liang, Ridgway, Rachel, Adams, Peter D., Anderson, Kurt I., Gottlieb, Eyal, Sansom, Owen J., Ryan, Kevin M.
Published in Nature (London) (12.12.2013)
Published in Nature (London) (12.12.2013)
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The role of autophagy in tumour development and cancer therapy
Rosenfeldt, Mathias T., Ryan, Kevin M.
Published in Expert reviews in molecular medicine (01.12.2009)
Published in Expert reviews in molecular medicine (01.12.2009)
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Journal Article
MYC- and MIZ1-Dependent Vesicular Transport of Double-Strand RNA Controls Immune Evasion in Pancreatic Ductal Adenocarcinoma
Krenz, Bastian, Gebhardt-Wolf, Anneli, Ade, Carsten P, Gaballa, Abdallah, Roehrig, Florian, Vendelova, Emilia, Baluapuri, Apoorva, Eilers, Ursula, Gallant, Peter, D'Artista, Luana, Wiegering, Armin, Gasteiger, Georg, Rosenfeldt, Mathias T, Bauer, Stefan, Zender, Lars, Wolf, Elmar, Eilers, Martin
Published in Cancer research (Chicago, Ill.) (15.08.2021)
Published in Cancer research (Chicago, Ill.) (15.08.2021)
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USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer
Maier, Carina R., Hartmann, Oliver, Prieto-Garcia, Cristian, Al-Shami, Kamal M., Schlicker, Lisa, Vogel, Felix C. E., Haid, Silke, Klann, Kevin, Buck, Viktoria, Münch, Christian, Schmitz, Werner, Einig, Elias, Krenz, Bastian, Calzado, Marco A., Eilers, Martin, Popov, Nikita, Rosenfeldt, Mathias T., Diefenbacher, Markus E., Schulze, Almut
Published in Cell death and differentiation (01.07.2023)
Published in Cell death and differentiation (01.07.2023)
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Acute systemic knockdown of Atg7 is lethal and causes pancreatic destruction in shRNA transgenic mice
Mainz, Laura, Sarhan, Mohamed A. F. E., Roth, Sabine, Sauer, Ursula, Kalogirou, Charis, Eckstein, Markus, Gerhard-Hartmann, Elena, Seibert, Helen-Desiree, Voelker, Hans-Ulrich, Geppert, Carol, Rosenwald, Andreas, Eilers, Martin, Schulze, Almut, Diefenbacher, Markus, Rosenfeldt, Mathias T.
Published in Autophagy (02.12.2022)
Published in Autophagy (02.12.2022)
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Journal Article
CD20-Targeting Immunotherapy Promotes Cellular Senescence in B-Cell Lymphoma
Däbritz, J Henry M, Yu, Yong, Milanovic, Maja, Schönlein, Martin, Rosenfeldt, Mathias T, Dörr, Jan R, Kaufmann, Andreas M, Dörken, Bernd, Schmitt, Clemens A
Published in Molecular cancer therapeutics (01.05.2016)
Published in Molecular cancer therapeutics (01.05.2016)
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LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer
Rudalska, Ramona, Harbig, Jule, Snaebjornsson, Marteinn T, Klotz, Sabrina, Zwirner, Stefan, Taranets, Liudmyla, Heinzmann, Florian, Kronenberger, Thales, Forster, Michael, Cui, Wei, D'Artista, Luana, Einig, Elias, Hinterleitner, Martina, Schmitz, Werner, Dylawerska, Agata, Kang, Tae-Won, Poso, Antti, Rosenfeldt, Mathias T, Malek, Nisar P, Bitzer, Michael, Laufer, Stefan, Pichler, Bernd J, Popov, Nikita, Schulze, Almut, Zender, Lars, Dauch, Daniel
Published in Nature cancer (01.02.2021)
Published in Nature cancer (01.02.2021)
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The organomercurial 4-aminophenylmercuric acetate, independent of matrix metalloproteinases, induces dose-dependent activation/inhibition of platelet aggregation
Rosenfeldt, Mathias T, Valentino, Michael, Labruzzo, Salvatore, Scudder, Lesley, Pavlaki, Maria, Cao, Jian, Vacirca, Jeffrey, Bahou, Wadie F, Zucker, Stanley
Published in Thrombosis and haemostasis (01.02.2005)
Published in Thrombosis and haemostasis (01.02.2005)
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Elevated ROS Levels in Response to CD20-Targeting Enhance Senescence Entry after Immunochemotherapy in Human B-Cell Lymphoma
Däbritz, J. Henry M., Yu, Yong, Milanovic, Maja, Dörr, Jan R., Kaufmann, Andreas M., Rosenfeldt, Mathias T., Dörken, Bernd, Schmitt, Clemens A.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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