Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes
Zhu, Zengrong, Li, Qing V., Lee, Kihyun, Rosen, Bess P., González, Federico, Soh, Chew-Li, Huangfu, Danwei
Published in Cell stem cell (02.06.2016)
Published in Cell stem cell (02.06.2016)
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Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions
Luo, Renhe, Yan, Jielin, Oh, Jin Woo, Xi, Wang, Shigaki, Dustin, Wong, Wilfred, Cho, Hyein S., Murphy, Dylan, Cutler, Ronald, Rosen, Bess P., Pulecio, Julian, Yang, Dapeng, Glenn, Rachel A., Chen, Tingxu, Li, Qing V., Vierbuchen, Thomas, Sidoli, Simone, Apostolou, Effie, Huangfu, Danwei, Beer, Michael A.
Published in Nature genetics (01.08.2023)
Published in Nature genetics (01.08.2023)
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Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness
Rosen, Bess P., Li, Qing V., Cho, Hyein S., Liu, Dingyu, Yang, Dapeng, Graff, Sarah, Yan, Jielin, Luo, Renhe, Verma, Nipun, Damodaran, Jeyaram R., Kale, Hanuman T., Kaplan, Samuel J., Beer, Michael A., Sidoli, Simone, Huangfu, Danwei
Published in Nature communications (17.10.2024)
Published in Nature communications (17.10.2024)
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QSER1 protects DNA methylation valleys from de novo methylation
Dixon, Gary, Pan, Heng, Yang, Dapeng, Rosen, Bess P, Jashari, Therande, Verma, Nipun, Pulecio, Julian, Caspi, Inbal, Lee, Kihyun, Stransky, Stephanie, Glezer, Abigail, Liu, Chang, Rivas, Marco, Kumar, Ritu, Lan, Yahui, Torregroza, Ingrid, He, Chuan, Sidoli, Simone, Evans, Todd, Elemento, Olivier, Huangfu, Danwei
Published in Science (American Association for the Advancement of Science) (09.04.2021)
Published in Science (American Association for the Advancement of Science) (09.04.2021)
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Genome-scale screens identify JNK–JUN signaling as a barrier for pluripotency exit and endoderm differentiation
Li, Qing V., Dixon, Gary, Verma, Nipun, Rosen, Bess P., Gordillo, Miriam, Luo, Renhe, Xu, Chunlong, Wang, Qiong, Soh, Chew-Li, Yang, Dapeng, Crespo, Miguel, Shukla, Abhijit, Xiang, Qing, Dündar, Friederike, Zumbo, Paul, Witkin, Matthew, Koche, Richard, Betel, Doron, Chen, Shuibing, Massagué, Joan, Garippa, Ralph, Evans, Todd, Beer, Michael A., Huangfu, Danwei
Published in Nature genetics (01.06.2019)
Published in Nature genetics (01.06.2019)
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CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction
Yang, Dapeng, Cho, Hyunwoo, Tayyebi, Zakieh, Shukla, Abhijit, Luo, Renhe, Dixon, Gary, Ursu, Valeria, Stransky, Stephanie, Tremmel, Daniel M., Sackett, Sara D., Koche, Richard, Kaplan, Samuel J., Li, Qing V., Park, Jiwoon, Zhu, Zengrong, Rosen, Bess P., Pulecio, Julian, Shi, Zhong-Dong, Bram, Yaron, Schwartz, Robert E., Odorico, Jon S., Sidoli, Simone, Wright, Christopher V., Leslie, Christina S., Huangfu, Danwei
Published in Nature cell biology (01.07.2022)
Published in Nature cell biology (01.07.2022)
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Glutamine independence is a selectable feature of pluripotent stem cells
Vardhana, Santosha A, Arnold, Paige K, Rosen, Bess P, Chen, Yanyang, Carey, Bryce W, Huangfu, Danwei, Carmona Fontaine, Carlos, Thompson, Craig B, Finley, Lydia W S
Published in Nature metabolism (01.07.2019)
Published in Nature metabolism (01.07.2019)
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Journal Article
Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions
Luo, Renhe, Yan, Jielin, Oh, Jin Woo, Xi, Wang, Shigaki, Dustin, Wong, Wilfred, Cho, Hyunwoo, Murphy, Dylan, Cutler, Ronald, Rosen, Bess P, Pulecio, Julian, Yang, Dapeng, Glenn, Rachel, Chen, Tingxu, Li, Qing V, Vierbuchen, Thomas, Sidoli, Simone, Apostolou, Effie, Huangfu, Danwei, Beer, Michael A
Published in bioRxiv : the preprint server for biology (09.03.2023)
Published in bioRxiv : the preprint server for biology (09.03.2023)
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Journal Article
Parallel genome-scale CRISPR-Cas9 screens uncouple human pluripotent stem cell identity versus fitness
Rosen, Bess P, Li, Qing V, Cho, Hyein S, Liu, Dingyu, Yang, Dapeng, Graff, Sarah, Yan, Jielin, Luo, Renhe, Verma, Nipun, Damodaran, Jeyaram R, Kale, Hanuman T, Kaplan, Samuel J, Beer, Michael A, Sidoli, Simone, Huangfu, Danwei
Published in bioRxiv (01.09.2024)
Published in bioRxiv (01.09.2024)
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