Prevention of Respiratory Syncytial Virus Infection in Healthy Adults by a Single Immunization of Ad26.RSV.preF in a Human Challenge Study
Sadoff, Jerald, De Paepe, Els, DeVincenzo, John, Gymnopoulou, Efi, Menten, Joris, Murray, Bryan, Rosemary Bastian, Arangassery, Vandebosch, An, Haazen, Wouter, Noulin, Nicolas, Comeaux, Christy, Heijnen, Esther, Eze, Kingsley, Gilbert, Anthony, Lambkin-Williams, Rob, Schuitemaker, Hanneke, Callendret, Benoit
Published in The Journal of infectious diseases (26.08.2022)
Published in The Journal of infectious diseases (26.08.2022)
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A Randomized, Double‐Blind, Placebo‐Controlled, Phase 1 Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of Single Vaccination of Ad26.RSV.preF‐Based Regimen in Japanese Adults Aged 60 Years and Older
Eto, Takashi, Okubo, Yusuke, Momose, Atsushi, Tamura, Hiroshi, Zheng, Richuan, Callendret, Benoit, Bastian, Arangassery Rosemary, Comeaux, Christy A.
Published in Influenza and other respiratory viruses (01.06.2024)
Published in Influenza and other respiratory viruses (01.06.2024)
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RSV A2-Based Prefusion F Vaccine Candidates Induce RSV A and RSV B Cross Binding and Neutralizing Antibodies and Provide Protection against RSV A and RSV B Challenge in Preclinical Models
Cox, Freek, Saeland, Eirikur, Thoma, Anne, van den Hoogen, Ward, Tettero, Lisanne, Drijver, Joke, Vaneman, Cornelis, van Polanen, Yolinda, Ritschel, Tina, Bastian, Arangassery Rosemary, Callendret, Benoit, Zahn, Roland, van der Fits, Leslie
Published in Vaccines (Basel) (01.03.2023)
Published in Vaccines (Basel) (01.03.2023)
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Phase 1 Safety and Immunogenicity Study of a Respiratory Syncytial Virus Vaccine With an Adenovirus 26 Vector Encoding Prefusion F (Ad26.RSV.preF) in Adults Aged ≥60 Years
Williams, Kristi, Bastian, Arangassery Rosemary, Feldman, Robert Allen, Omoruyi, Edmund, de Paepe, Els, Hendriks, Jenny, van Zeeburg, Hester, Godeaux, Olivier, Langedijk, Johannes P M, Schuitemaker, Hanneke, Sadoff, Jerry, Callendret, Benoit
Published in The Journal of infectious diseases (17.08.2020)
Published in The Journal of infectious diseases (17.08.2020)
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Concomitant Administration of Ad26.RSV.preF/RSV preF Protein Vaccine and High-Dose Influenza Vaccine in Adults 65 Years and Older: A Noninferiority Trial
Widagdo, Widagdo, Bastian, Arangassery Rosemary, Jastorff, Archana M, Scheys, Ilse, De Paepe, Els, Comeaux, Christy A, Ligtenberg, Nynke, Callendret, Benoit, Heijnen, Esther
Published in The Journal of infectious diseases (16.08.2024)
Published in The Journal of infectious diseases (16.08.2024)
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Long-term efficacy and immunogenicity of Ad26.RSV.preF–RSV preF protein vaccine (CYPRESS): a randomised, double-blind, placebo-controlled, phase 2b study
Falsey, Ann R, Hosman, Tessa, Bastian, Arangassery Rosemary, Vandenberghe, Sjouke, Chan, Eric K H, Douoguih, Macaya, Heijnen, Esther, Comeaux, Christy A, Callendret, Benoit, Allaw, Mohammed, Briskin, Toby, Brune, Daniel, Egelhof, Richard, Ervin, John, Falsey, Ann, Fierro, Carolos, Fried, David, Jackson-Booth, Peta-Gay, Kimmel, Murray, McGill, Lorrie, Nugent, Paul, Patel, Suchet, Rizzardi, Barbara, Ruhlmann, James, Strout, Cynthia, Tharenos, Leslie, Vachris, Timothy, Wadsworth, Tyler
Published in The Lancet infectious diseases (01.09.2024)
Published in The Lancet infectious diseases (01.09.2024)
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Immunogenicity, safety and reactogenicity of Ad26.RSV.preF/RSV preF protein vaccine in adults aged 60 to 75 years: A comparison of phase 2b and phase 3 clinical trial material
Jastorff, Archana, Bastian, Arangassery Rosemary, Ligtenberg, Nynke, Klyashtornyy, Vladislav, Callendret, Benoît, Heijnen, Esther
Published in Human vaccines & immunotherapeutics (31.12.2024)
Published in Human vaccines & immunotherapeutics (31.12.2024)
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Journal Article
Mechanism of Multivalent Nanoparticle Encounter with HIV-1 for Potency Enhancement of Peptide Triazole Virus Inactivation
Rosemary Bastian, Arangassery, Nangarlia, Aakansha, Bailey, Lauren D., Holmes, Andrew, Kalyana Sundaram, R. Venkat, Ang, Charles, Moreira, Diogo R.M., Freedman, Kevin, Duffy, Caitlin, Contarino, Mark, Abrams, Cameron, Root, Michael, Chaiken, Irwin
Published in The Journal of biological chemistry (02.01.2015)
Published in The Journal of biological chemistry (02.01.2015)
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Immunogenicity and safety of Ad26.RSV.preF/RSV preF protein vaccine at predicted intermediate- and end-of-shelf-life as an evaluation of potency throughout shelf life
Hosman, Tessa, van Heesbeen, Roy, Bastian, Arangassery Rosemary, Hu, Weihong, Comeaux, Christy, Ligtenberg, Nynke, van Montfort, Bart, Callendret, Benoît, Heijnen, Esther
Published in Human vaccines & immunotherapeutics (31.12.2024)
Published in Human vaccines & immunotherapeutics (31.12.2024)
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T cells, more than antibodies, may prevent symptoms developing from respiratory syncytial virus infections in older adults
Salaun, Bruno, De Smedt, Jonathan, Vernhes, Charlotte, Moureau, Annick, Öner, Deniz, Bastian, Arangassery Rosemary, Janssens, Michel, Balla-Jhagjhoorsingh, Sunita, Aerssens, Jeroen, Lambert, Christophe, Coenen, Samuel, Butler, Christopher C., Drysdale, Simon B., Wildenbeest, Joanne G., Pollard, Andrew J., Openshaw, Peter J. M., Bont, Louis
Published in Frontiers in immunology (13.10.2023)
Published in Frontiers in immunology (13.10.2023)
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Serum and mucosal antibody-mediated protection and identification of asymptomatic respiratory syncytial virus infection in community-dwelling older adults in Europe
Öner, Deniz, Vernhes, Charlotte, Balla-Jhagjhoorsingh, Sunita, Moureau, Annick, Crabbe, Marjolein, Salaun, Bruno, Bastian, Arangassery Rosemary, Thys, Kim, De Smedt, Jonathan, Ooft, Salo N., Korsten, Koos, Adriaenssens, Niels, Coenen, Samuel, Butler, Christopher C., Verheij, Theo J. M., Drysdale, Simon B., Wildenbeest, Joanne G., Pollard, Andrew J., Openshaw, Peter J. M., Bont, Louis, Aerssens, Jeroen
Published in Frontiers in immunology (18.10.2024)
Published in Frontiers in immunology (18.10.2024)
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Covalent Conjugation of a Peptide Triazole to HIV‑1 gp120 Enables Intramolecular Binding Site Occupancy
Emileh, Ali, Duffy, Caitlin, Holmes, Andrew P, Rosemary Bastian, Arangassery, Aneja, Rachna, Tuzer, Ferit, Rajagopal, Srivats, Li, Huiyuan, Abrams, Cameron F, Chaiken, Irwin M
Published in Biochemistry (Easton) (03.06.2014)
Published in Biochemistry (Easton) (03.06.2014)
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Disulfide Sensitivity in the Env Protein Underlies Lytic Inactivation of HIV‑1 by Peptide Triazole Thiols
Bailey, Lauren D, Kalyana Sundaram, Ramalingam Venkat, Li, Huiyuan, Duffy, Caitlin, Aneja, Rachna, Rosemary Bastian, Arangassery, Holmes, Andrew P, Kamanna, Kantharaju, Rashad, Adel A, Chaiken, Irwin
Published in ACS chemical biology (18.12.2015)
Published in ACS chemical biology (18.12.2015)
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Immunogenicity and safety of different dose levels of Ad26.RSV.preF/RSV preF protein vaccine in adults aged 60 years and older: A randomized, double-blind, placebo-controlled, phase 2a study
van Heesbeen, Roy, Bastian, Arangassery Rosemary, Omoruyi, Edmund, Rosen, Jeffrey, Comeaux, Christy A., Callendret, Benoit, Heijnen, Esther
Published in Vaccine (02.12.2024)
Published in Vaccine (02.12.2024)
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Antibody effector functions are associated with protection from respiratory syncytial virus
Bartsch, Yannic C., Cizmeci, Deniz, Kang, Jaewon, Zohar, Tomer, Periasamy, Sivakumar, Mehta, Nickita, Tolboom, Jeroen, Van der Fits, Leslie, Sadoff, Jerry, Comeaux, Christy, Callendret, Benoit, Bukreyev, Alexander, Lauffenburger, Douglas A., Bastian, Arangassery Rosemary, Alter, Galit
Published in Cell (22.12.2022)
Published in Cell (22.12.2022)
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Safety, Immunogenicity, and Regimen Selection of Ad26.RSV.preF–Based Vaccine Combinations: A Randomized, Double-blind, Placebo-Controlled, Phase 1/2a Study
Comeaux, Christy A, Bart, Stephan, Bastian, Arangassery Rosemary, Klyashtornyy, Vladislav, De Paepe, Els, Omoruyi, Edmund, van der Fits, Leslie, van Heesbeen, Roy, Heijnen, Esther, Callendret, Benoit, Sadoff, Jerald
Published in The Journal of infectious diseases (12.01.2024)
Published in The Journal of infectious diseases (12.01.2024)
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Safety and immunogenicity of the Ad26/protein preF RSV vaccine in adults aged 18 to 59 years with and without at-risk comorbidities for severe respiratory syncytial virus disease: A phase 3, randomized, controlled, immunobridging trial
Jastorff, Archana, Gymnopoulou, Efi, Salas, Jose, Merrall, Elizabeth, Buntinx, Erik, Martin, Charlotte, Askling, Helena H., Schenkenberger, Isabelle, Yuste, Angela Cano, Smith, William, Sotolongo, Roberto, Von Engelhardt, Charlotte, Bastian, Arangassery Rosemary, Comeaux, Christy, Ligtenberg, Nynke, Callendret, Benoit, Heijnen, Esther
Published in Vaccine (01.01.2025)
Published in Vaccine (01.01.2025)
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Vaccine-induced antibody Fc-effector functions in humans immunized with a combination Ad26.RSV.preF/RSV preF protein vaccine
Bartsch, Yannic C, Cizmeci, Deniz, Yuan, Dansu, Mehta, Nickita, Tolboom, Jeroen, De Paepe, Els, van Heesbeen, Roy, Sadoff, Jerald, Comeaux, Christy A, Heijnen, Esther, Callendret, Benoit, Alter, Galit, Bastian, Arangassery Rosemary
Published in Journal of virology (30.11.2023)
Published in Journal of virology (30.11.2023)
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Phase 1/2a Safety and Immunogenicity of an Adenovirus 26 Vector Respiratory Syncytial Virus (RSV) Vaccine Encoding Prefusion F in Adults 18-50 Years and RSV-Seropositive Children 12-24 Months
Stuart, Arabella S V, Virta, Miia, Williams, Kristi, Seppa, Ilkka, Hartvickson, Robyn, Greenland, Melanie, Omoruyi, Edmund, Bastian, Arangassery Rosemary, Haazen, Wouter, Salisch, Nadine, Gymnopoulou, Efi, Callendret, Benoit, Faust, Saul N, Snape, Matthew D, Heijnen, Esther
Published in The Journal of infectious diseases (28.12.2022)
Published in The Journal of infectious diseases (28.12.2022)
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