A General Synthesis of Dihydronaphthyridinones with Aryl-Substituted Quaternary Benzylic Centers
Murray, John C., Rose, Colin R., Curto, John M.
Published in Journal of organic chemistry (03.03.2023)
Published in Journal of organic chemistry (03.03.2023)
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Preparation of Azinones from (Cyclopropylmethoxy)azine Ethers
Londregan, Allyn T., Curto, John M., Hastry, Emma, Rose, Colin R., Berritt, Simon
Published in Journal of organic chemistry (05.05.2023)
Published in Journal of organic chemistry (05.05.2023)
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Journal Article
Cross-Laminated Secondary Timber: Experimental Testing and Modelling the Effect of Defects and Reduced Feedstock Properties
Rose, Colin, Bergsagel, Dan, Dufresne, Thibault, Unubreme, Evi, Lyu, Tianyao, Duffour, Philippe, Stegemann, Julia
Published in Sustainability (09.11.2018)
Published in Sustainability (09.11.2018)
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Discovery and Preclinical Characterization of 6‑Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]‑1H‑indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy
Cameron, Kimberly O, Kung, Daniel W, Kalgutkar, Amit S, Kurumbail, Ravi G, Miller, Russell, Salatto, Christopher T, Ward, Jessica, Withka, Jane M, Bhattacharya, Samit K, Boehm, Markus, Borzilleri, Kris A, Brown, Janice A, Calabrese, Matthew, Caspers, Nicole L, Cokorinos, Emily, Conn, Edward L, Dowling, Matthew S, Edmonds, David J, Eng, Heather, Fernando, Dilinie P, Frisbie, Richard, Hepworth, David, Landro, James, Mao, Yuxia, Rajamohan, Francis, Reyes, Allan R, Rose, Colin R, Ryder, Tim, Shavnya, Andre, Smith, Aaron C, Tu, Meihua, Wolford, Angela C, Xiao, Jun
Published in Journal of medicinal chemistry (08.09.2016)
Published in Journal of medicinal chemistry (08.09.2016)
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Journal Article
When and Why Statins Fail to Save Lives
Vos, Eddie, Nguyen, Paul V., Biron, Pierre, Rose, Colin P.
Published in The American journal of medicine (01.09.2017)
Published in The American journal of medicine (01.09.2017)
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Journal Article
6-Azaspiro[2.5]octanes as small molecule agonists of the human glucagon-like peptide-1 receptor
Aspnes, Gary E., Bagley, Scott W., Coffey, Steven B., Conn, Edward L., Curto, John M., Edmonds, David J., Genovino, Julien, Griffith, David A., Ingle, Gajendra, Jiao, Wenhua, Limberakis, Chris, Mathiowetz, Alan M., Piotrowski, David W., Rose, Colin R., Ruggeri, Roger B., Wei, Liuqing
Published in Bioorganic & medicinal chemistry letters (01.10.2023)
Published in Bioorganic & medicinal chemistry letters (01.10.2023)
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Journal Article
Design and Identification of a Novel, Functionally Subtype Selective GABA(A) Positive Allosteric Modulator (PF-06372865)
Owen, Robert M., Blakemore, David, Cao, Lishuan, Flanagan, Neil, Fish, Rebecca, Gibson, Karl R., Gurrell, Rachel, Huh, Chan Woo, Kammonen, Juha, Mortimer-Cassen, Elisabeth, Nickolls, Sarah A., Omoto, Kiyoyuki, Owen, Dafydd, Pike, Andy, Pryde, David C., Reynolds, David S., Roeloffs, Rosemarie, Rose, Colin, Stead, Clara, Takeuchi, Mifune, Warmus, Joseph S., Watson, Christine
Published in Journal of medicinal chemistry (27.06.2019)
Published in Journal of medicinal chemistry (27.06.2019)
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Journal Article
A gene-based SNP resource and linkage map for the copepod Tigriopus californicus
Foley, Brad R, Rose, Colin G, Rundle, Daniel E, Leong, Wai, Moy, Gary W, Burton, Ronald S, Edmands, Suzanne
Published in BMC genomics (21.11.2011)
Published in BMC genomics (21.11.2011)
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Journal Article
Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes
Storer, R. Ian, Pike, Andy, Swain, Nigel A., Alexandrou, Aristos J., Bechle, Bruce M., Blakemore, David C., Brown, Alan D., Castle, Neil A., Corbett, Matthew S., Flanagan, Neil J., Fengas, David, Johnson, M. Scott, Jones, Lyn H., Marron, Brian E., Payne, C. Elizabeth, Printzenhoff, David, Rawson, David J., Rose, Colin R., Ryckmans, Thomas, Sun, Jianmin, Theile, Jonathan W., Torella, Rubben, Tseng, Elaine, Warmus, Joseph S.
Published in Bioorganic & medicinal chemistry letters (01.11.2017)
Published in Bioorganic & medicinal chemistry letters (01.11.2017)
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Journal Article
The Synthesis of Methyl-Substituted Spirocyclic Piperidine-Azetidine (2,7-Diazaspiro[3.5]nonane) and Spirocyclic Piperidine-Pyrrolidine (2,8-Diazaspiro[4.5]decane) Ring Systems
Smith, Aaron C, Cabral, Shawn, Kung, Daniel W, Rose, Colin R, Southers, James A, García-Irizarry, Carmen N, Damon, David B, Bagley, Scott W, Griffith, David A
Published in Journal of organic chemistry (06.05.2016)
Published in Journal of organic chemistry (06.05.2016)
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Journal Article
Practical synthesis of capromorelin, a growth hormone secretagogue, via a crystallization-induced dynamic resolution
Rose, Colin R., Zawistoski, Michael P., Lefker, Bruce A., Mangano, F. Michael, Wright, Ann S., Carpino, Philip A.
Published in Bioorganic & medicinal chemistry (01.02.2017)
Published in Bioorganic & medicinal chemistry (01.02.2017)
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Journal Article
Letter by Vos et al regarding article, "Statins for the primary prevention of cardiovascular events in women with elevated high-sensitivity C-reactive protein or dyslipidemia: results from the Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) and meta-analysis of women from primary prevention trials"
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One-Pot Synthesis of α‑Branched N‑Acylamines via Titanium-Mediated Condensation of Amides, Aldehydes, and Organometallics
Dai, Chunhui, Genovino, Julien, Bechle, Bruce M, Corbett, Matthew S, Huh, Chan Woo, Rose, Colin R, Sun, Jianmin, Warmus, Joseph S, Blakemore, David C
Published in Organic letters (03.03.2017)
Published in Organic letters (03.03.2017)
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Journal Article
Diastereoselective Synthesis of β‑Heteroaryl syn-α-Methyl-β-Amino Acid Derivatives via a Double Chiral Auxiliary Approach
Bian, Jianwei, Blakemore, David, Warmus, Joseph S, Sun, Jianmin, Corbett, Matthew, Rose, Colin R, Bechle, Bruce M
Published in Organic letters (01.02.2013)
Published in Organic letters (01.02.2013)
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Journal Article
Discovery of SARS-CoV-2 papain-like protease (PL pro ) inhibitors with efficacy in a murine infection model
Garnsey, Michelle R, Robinson, Matthew C, Nguyen, Luong T, Cardin, Rhonda, Tillotson, Joseph, Mashalidis, Ellene, Yu, Aijia, Aschenbrenner, Lisa, Balesano, Amanda, Behzadi, Amin, Boras, Britton, Chang, Jeanne S, Eng, Heather, Ephron, Andrew, Foley, Tim, Ford, Kristen K, Frick, James M, Gibson, Scott, Hao, Li, Hurst, Brett, Kalgutkar, Amit S, Korczynska, Magdalena, Lengyel-Zhand, Zsofia, Gao, Liping, Meredith, Hannah R, Patel, Nandini C, Polivkova, Jana, Rai, Devendra, Rose, Colin R, Rothan, Hussin, Sakata, Sylvie K, Vargo, Thomas R, Qi, Wenying, Wu, Huixian, Liu, Yiping, Yurgelonis, Irina, Zhang, Jinzhi, Zhu, Yuao, Zhang, Lei, Lee, Alpha A
Published in Science advances (30.08.2024)
Published in Science advances (30.08.2024)
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Journal Article
Evolution of the Synthesis of AMPK Activators for the Treatment of Diabetic Nephropathy: From Three Preclinical Candidates to the Investigational New Drug PF-06409577
Smith, Aaron C, Kung, Daniel W, Shavnya, Andre, Brandt, Thomas A, Dent, Philip D, Genung, Nathan E, Cabral, Shawn, Panteleev, Jane, Herr, Michael, Yip, Ka Ning, Aspnes, Gary E, Conn, Edward L, Dowling, Matthew S, Edmonds, David J, Edmonds, Ian D, Fernando, Dilinie P, Herrinton, Paul M, Keene, Nandell F, Lavergne, Sophie Y, Li, Qifang, Polivkova, Jana, Rose, Colin R, Thuma, Benjamin A, Vetelino, Michael G, Wang, Guoqiang, Weaver, John D, Widlicka, Daniel W, Price Wiglesworth, Kristin E, Xiao, Jun, Zahn, Todd, Zhang, Yingxin
Published in Organic process research & development (15.06.2018)
Published in Organic process research & development (15.06.2018)
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Design and development of histone deacetylase (HDAC) chemical probes for cell-based profiling
Albrow, Victoria E, Grimley, Rachel L, Clulow, James, Rose, Colin R, Sun, Jianmin, Warmus, Joseph S, Tate, Edward W, Jones, Lyn H, Storer, R Ian
Published in Molecular bioSystems (01.01.2016)
Published in Molecular bioSystems (01.01.2016)
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Journal Article
Point: Why statins have failed to reduce mortality in just about anybody
Vos, Eddie, MEng, Rose, Colin P., MD, PhD, Biron, Pierre, MD
Published in Journal of clinical lipidology (01.05.2013)
Published in Journal of clinical lipidology (01.05.2013)
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