NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area
Borruto, Anna Maria, Fotio, Yannick, Stopponi, Serena, Brunori, Gloria, Petrella, Michele, Caputi, Francesca Felicia, Romualdi, Patrizia, Candeletti, Sanzio, Narendran, Rajesh, Rorick‐Kehn, Linda M., Ubaldi, Massimo, Weiss, Friedbert, Ciccocioppo, Roberto
Published in British journal of pharmacology (01.04.2020)
Published in British journal of pharmacology (01.04.2020)
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NOP Receptor Antagonists Decrease Alcohol Drinking in the Dark in C57BL/6J Mice
Brunori, Gloria, Weger, Michelle, Schoch, Jennifer, Targowska‐Duda, Katarzyna, Barnes, Megan, Borruto, Anna Maria, Rorick‐Kehn, Linda M., Zaveri, Nurulain T., Pintar, John E., Ciccocioppo, Roberto, Toll, Lawrence, Cippitelli, Andrea
Published in Alcoholism, clinical and experimental research (01.10.2019)
Published in Alcoholism, clinical and experimental research (01.10.2019)
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A Novel, Orally Bioavailable Nociceptin Receptor Antagonist, LY2940094, Reduces Ethanol Self-Administration and Ethanol Seeking in Animal Models
Rorick-Kehn, Linda M., Ciccocioppo, Roberto, Wong, Conrad J., Witkin, Jeffrey M., Martinez-Grau, Maria A., Stopponi, Serena, Adams, Benjamin L., Katner, Jason S., Perry, Kenneth W., Toledo, Miguel A., Diaz, Nuria, Lafuente, Celia, Jiménez, Alma, Benito, Ana, Pedregal, Concepción, Weiss, Friedbert, Statnick, Michael A.
Published in Alcoholism, clinical and experimental research (01.05.2016)
Published in Alcoholism, clinical and experimental research (01.05.2016)
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In vivo pharmacological characterization of the structurally novel, potent, selective mGlu2/3 receptor agonist LY404039 in animal models of psychiatric disorders
RORICK-KEHN, Linda M, JOHNSON, Bryan G, SCHOEPP, Darryle D, KNITOWSKI, Karen M, SALHOFF, Craig R, WITKIN, Jeffrey M, PERRY, Kenneth W, GRIFFEY, Kelly I, TIZZANO, Joseph P, MONN, James A, MCKINZIE, David L
Published in Psychopharmacologia (01.07.2007)
Published in Psychopharmacologia (01.07.2007)
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Pharmacological and Pharmacokinetic Properties of a Structurally Novel, Potent, and Selective Metabotropic Glutamate 2/3 Receptor Agonist: In Vitro Characterization of Agonist (â)-(1R,4S,5S,6S)-4-Amino-2-sulfonylbicyclo[3.1.0]-hexane-4,6-dicarboxylic Acid (LY404039)
Rorick-Kehn, Linda M, Johnson, Bryan G, Burkey, Jennifer L, Wright, Rebecca A, Calligaro, David O, Marek, Gerard J, Nisenbaum, Eric S, Catlow, John T, Kingston, Ann E, Giera, Deborah D, Herin, Marc F, Monn, James A, McKinzie, David L, Schoepp, Darryle D
Published in The Journal of pharmacology and experimental therapeutics (01.04.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2007)
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LSN2424100: a novel, potent orexin-2 receptor antagonist with selectivity over orexin-1 receptors and activity in an animal model predictive of antidepressant-like efficacy
Fitch, Thomas E, Benvenga, Mark J, Jesudason, Cynthia D, Zink, Charity, Vandergriff, Amy B, Menezes, Michelle M, Schober, Douglas A, Rorick-Kehn, Linda M
Published in Frontiers in neuroscience (2014)
Published in Frontiers in neuroscience (2014)
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Preclinical findings predicting efficacy and side‐effect profile of LY2940094, an antagonist of nociceptin receptors
Witkin, Jeffrey M., Rorick‐Kehn, Linda M., Benvenga, Mark J., Adams, Benjamin L., Gleason, Scott D., Knitowski, Karen M., Li, Xia, Chaney, Steven, Falcone, Julie F., Smith, Janice W., Foss, Julie, Lloyd, Kirsti, Catlow, John T., McKinzie, David L., Svensson, Kjell A., Barth, Vanessa N., Toledo, Miguel A., Diaz, Nuria, Lafuente, Celia, Jiménez, Alma, Benito, Alfonso, Pedregal, Conception, Martínez‐Grau, Maria A., Post, Anke, Ansonoff, Michael A., Pintar, John E., Statnick, Michael A.
Published in Pharmacology research & perspectives (01.12.2016)
Published in Pharmacology research & perspectives (01.12.2016)
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Improved Bioavailability of the mGlu2/3 Receptor Agonist LY354740 Using a Prodrug Strategy: In Vivo Pharmacology of LY544344
Rorick-Kehn, Linda M, Perkins, Everett J, Knitowski, Karen M, Hart, John C, Johnson, Bryan G, Schoepp, Darryle D, McKinzie, David L
Published in The Journal of pharmacology and experimental therapeutics (01.02.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2006)
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The biology of Nociceptin/Orphanin FQ(N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence
WITKIN, Jeffrey M, STATNICK, Michael A, RORICK-KEHN, Linda M, PINTAR, John E, ANSONOFF, Michael, YANYUN CHEN, TUCKER, R. Craig, CICCOCIOPPO, Roberto
Published in Pharmacology & therapeutics (Oxford) (01.03.2014)
Published in Pharmacology & therapeutics (Oxford) (01.03.2014)
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Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction
Kallupi, Marsida, Scuppa, Giulia, de Guglielmo, Giordano, Calò, Girolamo, Weiss, Friedbert, Statnick, Michael A, Rorick-Kehn, Linda M, Ciccocioppo, Roberto
Published in Neuropsychopharmacology (New York, N.Y.) (01.02.2017)
Published in Neuropsychopharmacology (New York, N.Y.) (01.02.2017)
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LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders
Rorick-Kehn, Linda M., Witkin, Jeffrey M., Statnick, Michael A., Eberle, Elizabeth L., McKinzie, Jamie H., Kahl, Steven D., Forster, Beth M., Wong, Conrad J., Li, Xia, Crile, Robert S., Shaw, David B., Sahr, Allison E., Adams, Benjamin L., Quimby, Steven J., Diaz, Nuria, Jimenez, Alma, Pedregal, Concepcion, Mitch, Charles H., Knopp, Kelly L., Anderson, Wesley H., Cramer, Jeffrey W., McKinzie, David L.
Published in Neuropharmacology (01.02.2014)
Published in Neuropharmacology (01.02.2014)
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Determining pharmacological selectivity of the kappa opioid receptor antagonist LY2456302 using pupillometry as a translational biomarker in rat and human
Rorick-Kehn, Linda M, Witcher, Jennifer W, Lowe, Stephen L, Gonzales, Celedon R, Weller, Mary Ann, Bell, Robert L, Hart, John C, Need, Anne B, McKinzie, Jamie H, Statnick, Michael A, Suico, Jeffrey G, McKinzie, David L, Tauscher-Wisniewski, Sitra, Mitch, Charles H, Stoltz, Randall R, Wong, Conrad J
Published in The international journal of neuropsychopharmacology (01.01.2015)
Published in The international journal of neuropsychopharmacology (01.01.2015)
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Preclinical findings predicting efficacy and side‐effect profile of LY 2940094, an antagonist of nociceptin receptors
Witkin, Jeffrey M., Rorick‐Kehn, Linda M., Benvenga, Mark J., Adams, Benjamin L., Gleason, Scott D., Knitowski, Karen M., Li, Xia, Chaney, Steven, Falcone, Julie F., Smith, Janice W., Foss, Julie, Lloyd, Kirsti, Catlow, John T., McKinzie, David L., Svensson, Kjell A., Barth, Vanessa N., Toledo, Miguel A., Diaz, Nuria, Lafuente, Celia, Jiménez, Alma, Benito, Alfonso, Pedregal, Conception, Martínez‐Grau, Maria A., Post, Anke, Ansonoff, Michael A., Pintar, John E., Statnick, Michael A.
Published in Pharmacology research & perspectives (01.12.2016)
Published in Pharmacology research & perspectives (01.12.2016)
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Corrigendum to “The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence” [Pharmacology & Therapeutics 141 (2014) 283–299]
Witkin, Jeffrey M., Statnick, Michael A., Rorick-Kehn, Linda M., Pintar, John E., Ansonoff, Michael, Chen, Yanyun, Craig Tucker, R., Ciccocioppo, Roberto
Published in Pharmacology & therapeutics (Oxford) (01.09.2014)
Published in Pharmacology & therapeutics (Oxford) (01.09.2014)
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The Biology of Nociceptin/Orphanin FQ (N/OFQ) Related to Obesity, Stress, Anxiety, Mood, and Drug Dependence1
Witkin, Jeffrey M., Statnick, Michael A., Rorick-Kehn, Linda M., Pintar, John E., Ansonoff, Michael, Chen, Yanyun, Tucker, R. Craig, Ciccocioppo, Roberto
Published in Pharmacology & therapeutics (Oxford) (01.11.2013)
Published in Pharmacology & therapeutics (Oxford) (01.11.2013)
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