An Automated Continuous Synthesis and Isolation for the Scalable Production of Aryl Sulfonyl Chlorides
Glace, Matthew, Armstrong, Cameron, Puryear, Nathan, Bailey, Colin, Moazeni-Pourasil, Roudabeh Sadat, Scott, Drew, Abdelwahed, Sherif, Roper, Thomas D
Published in Molecules (Basel, Switzerland) (20.05.2023)
Published in Molecules (Basel, Switzerland) (20.05.2023)
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7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir
Ziegler, Robert E., Desai, Bimbisar K., Jee, Jo‐Ann, Gupton, B. Frank, Roper, Thomas D., Jamison, Timothy F.
Published in Angewandte Chemie International Edition (11.06.2018)
Published in Angewandte Chemie International Edition (11.06.2018)
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3D Printing of Metformin HCl PVA Tablets by Fused Deposition Modeling: Drug Loading, Tablet Design, and Dissolution Studies
Ibrahim, Mariam, Barnes, Morgan, McMillin, Robert, Cook, Daniel W., Smith, Sarah, Halquist, Mathew, Wijesinghe, Dayanjan, Roper, Thomas D.
Published in AAPS PharmSciTech (01.07.2019)
Published in AAPS PharmSciTech (01.07.2019)
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Self-Assembly of pH-Labile Polymer Nanoparticles for Paclitaxel Prodrug Delivery: Formulation, Characterization, and Evaluation
Levit, Shani L, Gade, Narendar Reddy, Roper, Thomas D, Yang, Hu, Tang, Christina
Published in International journal of molecular sciences (05.12.2020)
Published in International journal of molecular sciences (05.12.2020)
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Practical Synthesis of 7-Bromo-4-chloro-1H-indazol-3-amine: An Important Intermediate to Lenacapavir
Asad, Naeem, Lyons, Michael, Muniz Machado Rodrigues, Shirley, Burns, Justina M, Roper, Thomas D, Laidlaw, G. Michael, Ahmad, Saeed, Gupton, B. Frank, Klumpp, Douglas, Jin, Limei
Published in Molecules (Basel, Switzerland) (01.06.2024)
Published in Molecules (Basel, Switzerland) (01.06.2024)
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Encapsulation of a highly hydrophilic drug in polymeric particles: A comparative study of batch and microfluidic processes
Aboelela, Sarah S., Ibrahim, Mariam, Badruddoza, Abu Zayed M., Tran, Valerie, Ferri, James K., Roper, Thomas D.
Published in International journal of pharmaceutics (05.09.2021)
Published in International journal of pharmaceutics (05.09.2021)
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Development of a continuous synthesis process for carbamazepine using validated in-line Raman spectroscopy and kinetic modelling for disturbance simulation
Glace, Matthew, Wu, Wei, Kraus, Harrison, Acevedo, David, Roper, Thomas D, Mohammad, Adil
Published in Reaction chemistry & engineering (02.05.2023)
Published in Reaction chemistry & engineering (02.05.2023)
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The Application of a Continuous Grignard Reaction in the Preparation of Fluconazole
Korwar, Sudha, Amir, Somi, Tosso, Perrer N., Desai, Bimbisar K., Kong, Caleb J., Fadnis, Swara, Telang, Nakul S., Ahmad, Saeed, Roper, Thomas D., Gupton, B. Frank
Published in European journal of organic chemistry (01.12.2017)
Published in European journal of organic chemistry (01.12.2017)
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Characterization and transcription of arsenic respiration and resistance genes during in situ uranium bioremediation
Giloteaux, Ludovic, Holmes, Dawn E, Williams, Kenneth H, Wrighton, Kelly C, Wilkins, Michael J, Montgomery, Alison P, Smith, Jessica A, Orellana, Roberto, Thompson, Courtney A, Roper, Thomas J, Long, Philip E, Lovley, Derek R
Published in The ISME Journal (01.02.2013)
Published in The ISME Journal (01.02.2013)
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Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic Acidemia
Armstrong, Allison J, Henke, Brad R, Collado, Maria Sol, Taylor, Justin M, Pourtaheri, Taylor D, Dillberger, John E, Roper, Thomas D, Wamhoff, Brian R, Olson, Matthew W, Figler, Robert A, Hoang, Stephen A, Reardon, John E, Johns, Brian A
Published in Journal of medicinal chemistry (22.04.2021)
Published in Journal of medicinal chemistry (22.04.2021)
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Journal Article
Enrichment of specific protozoan populations during in situ bioremediation of uranium-contaminated groundwater
Holmes, Dawn E, Giloteaux, Ludovic, Williams, Kenneth H, Wrighton, Kelly C, Wilkins, Michael J, Thompson, Courtney A, Roper, Thomas J, Long, Philip E, Lovley, Derek R
Published in The ISME Journal (01.07.2013)
Published in The ISME Journal (01.07.2013)
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Continuous flow synthesis of a pharmaceutical intermediate: a computational fluid dynamics approach
Armstrong, Cameron T, Pritchard, Cailean Q, Cook, Daniel W, Ibrahim, Mariam, Desai, Bimbisar K, Whitham, Patrick J, Marquardt, Brian J, Chen, Yizheng, Zoueu, Jeremie T, Bortner, Michael J, Roper, Thomas D
Published in Reaction chemistry & engineering (30.01.2019)
Published in Reaction chemistry & engineering (30.01.2019)
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Berichtigung: 7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir
Ziegler, Robert E., Desai, Bimbisar K., Jee, Jo‐Ann, Gupton, B. Frank, Roper, Thomas D., Jamison, Timothy F.
Published in Angewandte Chemie (12.11.2018)
Published in Angewandte Chemie (12.11.2018)
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Journal Article
7‐Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir
Ziegler, Robert E., Desai, Bimbisar K., Jee, Jo‐Ann, Gupton, B. Frank, Roper, Thomas D., Jamison, Timothy F.
Published in Angewandte Chemie (11.06.2018)
Published in Angewandte Chemie (11.06.2018)
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Journal Article
Synthesis of 4-Fluoro-β-(4-fluorophenyl)-l-phenylalanine by an Asymmetric Phase-Transfer Catalyzed Alkylation: Synthesis on Scale and Catalyst Stability
Patterson, Daniel E, Xie, Shiping, Jones, Lynda A, Osterhout, Martin H, Henry, Christopher G, Roper, Thomas D
Published in Organic process research & development (01.05.2007)
Published in Organic process research & development (01.05.2007)
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PAT Implementation on a Mobile Continuous Pharmaceutical Manufacturing System: Real-Time Process Monitoring with In-Line FTIR and Raman Spectroscopy
Miyai, Yuma, Formosa, Anna, Armstrong, Cameron, Marquardt, Brian, Rogers, Luke, Roper, Thomas
Published in Organic process research & development (17.12.2021)
Published in Organic process research & development (17.12.2021)
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The origin of greater than 200:1 enantioselectivity in a catalytic Diels-Alder reaction as revealed by physical and chemical studies
Corey, E. J, Loh, Teck Peng, Roper, Thomas D, Azimioara, Mihai D, Noe, Mark C
Published in Journal of the American Chemical Society (01.10.1992)
Published in Journal of the American Chemical Society (01.10.1992)
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Impurity Profiling for a Scalable Continuous Synthesis and Crystallization of Carbamazepine Drug Substance
Glace, Matthew, Kraus, Harrison, Wu, Wei, Acevedo, David, Liu, Dongxia, Roper, Thomas D., Mohammad, Adil
Published in Organic process research & development (17.05.2024)
Published in Organic process research & development (17.05.2024)
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