Serendipitous discovery of aryl boronic acids as β-lactamase inhibitors
Yang, Shu-Wei, Pan, Jianping, Root, Yuriko, Scapin, Giovanna, Xiao, Li, Su, Jing
Published in Bioorganic & medicinal chemistry letters (15.01.2020)
Published in Bioorganic & medicinal chemistry letters (15.01.2020)
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Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates
Mandal, Mihirbaran, Xiao, Li, Pan, Weidong, Scapin, Giovanna, Li, Guoqing, Tang, Haiqun, Yang, Shu-Wei, Pan, Jianping, Root, Yuriko, de Jesus, Reynalda Keh, Yang, Christine, Prosise, Winnie, Dayananth, Priya, Mirza, Asra, Therien, Alex G., Young, Katherine, Flattery, Amy, Garlisi, Charles, Zhang, Rumin, Chu, Donald, Sheth, Payal, Chu, Inhou, Wu, Jin, Markgraf, Carrie, Kim, Hai-Young, Painter, Ronald, Mayhood, Todd W., DiNunzio, Edward, Wyss, Daniel F., Buevich, Alexei V., Fischmann, Thierry, Pasternak, Alexander, Dong, Shuzhi, Hicks, Jacqueline D., Villafania, Artjohn, Liang, Lianzhu, Murgolo, Nicholas, Black, Todd, Hagmann, William K., Tata, Jim, Parmee, Emma R., Weber, Ann E., Su, Jing, Tang, Haifeng
Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
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Discovery of a vorapaxar analog with increased aqueous solubility
Xia, Yan, Chackalamannil, Samuel, Greenlee, William J., Wang, Yuguang, Hu, Zhiyong, Root, Yuriko, Wong, Jesse, Kong, Jianshe, Ahn, Ho-Sam, Boykow, George, Hsieh, Yunsheng, Kurowski, Stan, Chintala, Madhu
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
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