Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release
Foster, Daniel J., Wilson, Jermaine M., Remke, Daniel H., Mahmood, M. Suhaib, Uddin, M. Jashim, Wess, Jürgen, Patel, Sachin, Marnett, Lawrence J., Niswender, Colleen M., Jones, Carrie K., Xiang, Zixiu, Lindsley, Craig W., Rook, Jerri M., Conn, P. Jeffrey
Published in Neuron (Cambridge, Mass.) (21.09.2016)
Published in Neuron (Cambridge, Mass.) (21.09.2016)
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Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction
Walker, Adam G., Wenthur, Cody J., Xiang, Zixiu, Rook, Jerri M., Emmitte, Kyle A., Niswender, Colleen M., Lindsley, Craig W., Conn, P. Jeffrey
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2015)
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M1-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition
Moran, Sean P., Dickerson, Jonathan W., Cho, Hyekyung P., Xiang, Zixiu, Maksymetz, James, Remke, Daniel H., Lv, Xiaohui, Doyle, Catherine A., Rajan, Deepa H., Niswender, Colleen M., Engers, Darren W., Lindsley, Craig W., Rook, Jerri M., Conn, P. Jeffrey
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2018)
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2018)
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Journal Article
M 1 -positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition
Moran, Sean P, Dickerson, Jonathan W, Cho, Hyekyung P, Xiang, Zixiu, Maksymetz, James, Remke, Daniel H, Lv, Xiaohui, Doyle, Catherine A, Rajan, Deepa H, Niswender, Colleen M, Engers, Darren W, Lindsley, Craig W, Rook, Jerri M, Conn, P Jeffrey
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2018)
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2018)
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Development of a Selective and High Affinity Radioligand, [ 3 H]VU6013720, for the M 4 Muscarinic Receptor
Qi, Aidong, Kling, Haley E, Billard, Natasha, Rodriguez, Alice L, Peng, Li, Dickerson, Jonathan W, Engers, Julie L, Bender, Aaron M, Moehle, Mark S, Lindsley, Craig W, Rook, Jerri M, Niswender, Colleen M
Published in Molecular pharmacology (01.11.2023)
Published in Molecular pharmacology (01.11.2023)
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Mutual activation of glutamatergic mGlu4 and muscarinic M4 receptors reverses schizophrenia-related changes in rodents
Cieślik, Paulina, Woźniak, Monika, Rook, Jerri M., Tantawy, Mohammed N., Conn, P. Jeffrey, Acher, Francine, Tokarski, Krzysztof, Kusek, Magdalena, Pilc, Andrzej, Wierońska, Joanna M.
Published in Psychopharmacology (01.10.2018)
Published in Psychopharmacology (01.10.2018)
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Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M 4 Muscarinic Receptor
Moehle, Mark S, Pancani, Tristano, Byun, Nellie, Yohn, Samantha E, Wilson, 3rd, George H, Dickerson, Johnathan W, Remke, Daniel H, Xiang, Zixiu, Niswender, Colleen M, Wess, Jürgen, Jones, Carrie K, Lindsley, Craig W, Rook, Jerri M, Conn, P Jeffrey
Published in Neuron (Cambridge, Mass.) (20.12.2017)
Published in Neuron (Cambridge, Mass.) (20.12.2017)
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An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia
Balu, Darrick T, Li, Yan, Takagi, Shunsuke, Presti, Kendall Taylor, Ramikie, Teniel S, Rook, Jerri M, Jones, Carrie K, Lindsley, Craig W, Conn, P Jeffrey, Bolshakov, Vadim Y, Coyle, Joseph T
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2016)
Published in Neuropsychopharmacology (New York, N.Y.) (01.07.2016)
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Journal Article
Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M4 Muscarinic Receptor
Moehle, Mark S., Pancani, Tristano, Byun, Nellie, Yohn, Samantha E., Wilson, George H., Dickerson, Johnathan W., Remke, Daniel H., Xiang, Zixiu, Niswender, Colleen M., Wess, Jürgen, Jones, Carrie K., Lindsley, Craig W., Rook, Jerri M., Conn, P. Jeffrey
Published in Neuron (Cambridge, Mass.) (20.12.2017)
Published in Neuron (Cambridge, Mass.) (20.12.2017)
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CB2 Receptor Potentiation Mediates Antipsychotic-like Efficacy in Mice
Ferranti, Anthony S, Ishmam, Tazeen, Swann, Isaiah C, Du, Jennifer, Mariadoss, Janet, Craig, Lindsley W, Rook, Jerri M, Conn, Peter J, Foster, Daniel J
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Hyperactive Striatal Dopamine Signaling Observed in Huntington's Disease Mouse Models Prior to Motor Symptom Onset Can be Attenuated via Activation of M 4 Receptors
Rodriguez, Roland M, Foster, Daniel J, Lavery, Madigan L, Johnston, Curran M, Moehle, Mark S, Dickerson, Jonathon W, Rook, Jerri M, Conn, P J
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Tumor therapy by targeting extracellular hydroxyapatite using novel drugs: A paradigm shift
Tantawy, Mohammed N., McIntyre, J. Oliver, Yull, Fiona, Calcutt, M. Wade, Koktysh, Dmitry S., Wilson, Andrew J., Zu, Zhongliang, Nyman, Jeff, Rhoades, Julie, Peterson, Todd E., Colvin, Daniel, McCawley, Lisa J., Rook, Jerri. M., Fingleton, Barbara, Crispens, Marta Ann, Alvarez, Ronald D., Gore, John C.
Published in Cancer medicine (Malden, MA) (01.02.2024)
Published in Cancer medicine (Malden, MA) (01.02.2024)
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Allosteric activation of M₄ muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice
Pancani, Tristano, Foster, Daniel J., Moehle, Mark S., Bichell, Terry Jo, Bradley, Emma, Bridges, Thomas M., Klar, Rebecca, Poslusney, Mike, Rook, Jerri M., Daniels, J. Scott, Niswender, Colleen M., Jones, Carrie K., Wood, Michael R., Bowman, Aaron B., Lindsley, Craig W., Xiang, Zixiu, Conn, P. Jeffrey
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (10.11.2015)
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mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome
Gogliotti, Rocco G, Senter, Rebecca K, Rook, Jerri M, Ghoshal, Ayan, Zamorano, Rocio, Malosh, Chrysa, Stauffer, Shaun R, Bridges, Thomas M, Bartolome, Jose M, Daniels, J Scott, Jones, Carrie K, Lindsley, Craig W, Conn, P Jeffrey, Niswender, Colleen M
Published in Human molecular genetics (15.05.2016)
Published in Human molecular genetics (15.05.2016)
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Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity
Rodriguez, Alice L, Grier, Mark D, Jones, Carrie K, Herman, Elizabeth J, Kane, Alexander S, Smith, Randy L, Williams, Richard, Zhou, Ya, Marlo, Joy E, Days, Emily L, Blatt, Tasha N, Jadhav, Satyawan, Menon, Usha N, Vinson, Paige N, Rook, Jerri M, Stauffer, Shaun R, Niswender, Colleen M, Lindsley, Craig W, Weaver, C David, Conn, P Jeffrey
Published in Molecular pharmacology (01.12.2010)
Published in Molecular pharmacology (01.12.2010)
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Temporal Effects of Topical Morphine Application on Cutaneous Wound Healing
ROOK, Jerri M, HASAN, Wohaib, MCCARSON, Kenneth E
Published in Anesthesiology (Philadelphia) (01.07.2008)
Published in Anesthesiology (Philadelphia) (01.07.2008)
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