Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation
Chen, Serene W., Drakulic, Srdja, Deas, Emma, Ouberai, Myriam, Aprile, Francesco A., Arranz, Rocío, Ness, Samuel, Roodveldt, Cintia, Guilliams, Tim, De-Genst, Erwin J., Klenerman, David, Wood, Nicholas W., Knowles, Tuomas P.J., Alfonso, Carlos, Rivas, Germán, Abramov, Andrey Y., Valpuesta, José María, Dobson, Christopher M., Cremades, Nunilo
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (21.04.2015)
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Journal Article
Immune Signaling Kinases in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)
García-García, Raquel, Martín-Herrero, Laura, Blanca-Pariente, Laura, Pérez-Cabello, Jesús, Roodveldt, Cintia
Published in International journal of molecular sciences (10.12.2021)
Published in International journal of molecular sciences (10.12.2021)
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Journal Article
Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers
Mannini, Benedetta, Cascella, Roberta, Zampagni, Mariagioia, van Waarde-Verhagen, Maria, Meehan, Sarah, Roodveldt, Cintia, Campioni, Silvia, Boninsegna, Matilde, Penco, Amanda, Relini, Annalisa, Kampinga, Harm H, Dobson, Christopher M, Wilson, Mark R, Cecchi, Cristina, Chiti, Fabrizio
Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (31.07.2012)
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Journal Article
Extracellular TDP-43 aggregates target MAPK/MAK/MRK overlapping kinase (MOK) and trigger caspase-3/IL-18 signaling in microglia
Leal-Lasarte, María M, Franco, Jaime M, Labrador-Garrido, Adahir, Pozo, David, Roodveldt, Cintia
Published in The FASEB journal (01.07.2017)
Published in The FASEB journal (01.07.2017)
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Journal Article
The 'evolvability' of promiscuous protein functions
Tawfik, Dan S, Aharoni, Amir, Gaidukov, Leonid, Khersonsky, Olga, Gould, Stephen McQ, Roodveldt, Cintia
Published in Nature genetics (01.01.2005)
Published in Nature genetics (01.01.2005)
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Journal Article
Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation
Roodveldt, Cintia, Labrador-Garrido, Adahir, Gonzalez-Rey, Elena, Lachaud, Christian C, Guilliams, Tim, Fernandez-Montesinos, Rafael, Benitez-Rondan, Alicia, Robledo, Gema, Hmadcha, Abdelkrim, Delgado, Mario, Dobson, Christopher M, Pozo, David
Published in PloS one (13.11.2013)
Published in PloS one (13.11.2013)
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Journal Article
Hsp70 oligomerization is mediated by an interaction between the interdomain linker and the substrate-binding domain
Aprile, Francesco A, Dhulesia, Anne, Stengel, Florian, Roodveldt, Cintia, Benesch, Justin L P, Tortora, Paolo, Robinson, Carol V, Salvatella, Xavier, Dobson, Christopher M, Cremades, Nunilo
Published in PloS one (28.06.2013)
Published in PloS one (28.06.2013)
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Journal Article
Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants
Roodveldt, Cintia, Labrador-Garrido, Adahir, Gonzalez-Rey, Elena, Fernandez-Montesinos, Rafael, Caro, Marta, Lachaud, Christian C, Waudby, Christopher A, Delgado, Mario, Dobson, Christopher M, Pozo, David
Published in PloS one (26.10.2010)
Published in PloS one (26.10.2010)
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Journal Article
Editorial: Molecular Chaperones and Neurodegeneration
Roodveldt, Cintia, Outeiro, Tiago F, Braun, Janice E A
Published in Frontiers in neuroscience (11.10.2017)
Published in Frontiers in neuroscience (11.10.2017)
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Journal Article
Directed evolution of proteins for heterologous expression and stability
Roodveldt, Cintia, Aharoni, Amir, Tawfik, Dan S
Published in Current opinion in structural biology (01.02.2005)
Published in Current opinion in structural biology (01.02.2005)
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Journal Article
MAPK/MAK/MRK overlapping kinase (MOK) controls microglial inflammatory/type-I IFN responses via Brd4 and is involved in ALS
Pérez-Cabello, Jesús A, Silvera-Carrasco, Lucía, Franco, Jaime M, Capilla-González, Vivian, Armaos, Alexandros, Gómez-Lima, María, García-García, Raquel, Yap, Xin Wen, Leal-Lasarte, Magdalena, Lall, Deepti, Baloh, Robert H, Martínez, Salvador, Miyata, Yoshihiko, Tartaglia, Gian G, Sawarkar, Ritwick, García-Domínguez, Mario, Pozo, David, Roodveldt, Cintia
Published in Proceedings of the National Academy of Sciences - PNAS (11.07.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (11.07.2023)
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Journal Article
Use of Full-Length Recombinant Calflagin and Its C Fragment for Improvement of Diagnosis of Trypanosoma cruzi Infection
MARCIPAR, Ivan S, ROODVELDT, Cintia, CORRADI, Gerardo, CABEZA, Maria L, BRITO, Maria Edileuza F, FLEETER WINTER, Lucile M, MARCIPAR, Alberto J, SILBER, Ariel M
Published in Journal of Clinical Microbiology (01.11.2005)
Published in Journal of Clinical Microbiology (01.11.2005)
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Journal Article
Enzyme promiscuity: evolutionary and mechanistic aspects
Khersonsky, Olga, Roodveldt, Cintia, Tawfik, Dan S
Published in Current opinion in chemical biology (01.10.2006)
Published in Current opinion in chemical biology (01.10.2006)
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Journal Article
The immune system in Parkinson's disease: what we know so far
Roodveldt, Cintia, Bernardino, Liliana, Oztop-Cakmak, Ozgur, Dragic, Milorad, Fladmark, Kari Espolin, Ertan, Sibel, Busra, Aktas, Pita, Carlos, Ciglar, Lucia, Garraux, Gaetan, Williams-Gray, Caroline, Pacheco, Rodrigo, Romero-Ramos, Marina
Published in Brain (London, England : 1878) (04.06.2024)
Published in Brain (London, England : 1878) (04.06.2024)
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Immunological features of α‐synuclein in Parkinson's disease
Roodveldt, Cintia, Christodoulou, John, Dobson, Christopher M.
Published in Journal of cellular and molecular medicine (01.10.2008)
Published in Journal of cellular and molecular medicine (01.10.2008)
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Journal Article
The chaperonin CCT inhibits assembly of α-synuclein amyloid fibrils by a specific, conformation-dependent interaction
Sot, Begoña, Rubio-Muñoz, Alejandra, Leal-Quintero, Ahudrey, Martínez-Sabando, Javier, Marcilla, Miguel, Roodveldt, Cintia, Valpuesta, José M.
Published in Scientific reports (19.01.2017)
Published in Scientific reports (19.01.2017)
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