The mass balance recovery, absorption, metabolism, and excretion of [14C]-orvepitant in healthy male subjects after oral dosing: radiosynthesis of [14c]-orvepitant
Carver, David, Craig, Jo, Lawrence, Ron, Pawsey, Steve, Cousins, Peggy, Martos, Jose, Shaw, Iain
Published in Drug metabolism and pharmacokinetics (01.04.2024)
Published in Drug metabolism and pharmacokinetics (01.04.2024)
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Journal Article
Candidate Selection and Preclinical Evaluation of N-tert-Butyl Isoquine (GSK369796), An Affordable and Effective 4-Aminoquinoline Antimalarial for the 21st Century
O’Neill, Paul M, Park, B. Kevin, Shone, Alison E, Maggs, James L, Roberts, Phillip, Stocks, Paul A, Biagini, Giancarlo A, Bray, Patrick G, Gibbons, Peter, Berry, Neil, Winstanley, Peter A, Mukhtar, Amira, Bonar-Law, Richard, Hindley, Stephen, Bambal, Ramesh B, Davis, Charles B, Bates, Martin, Hart, Timothy K, Gresham, Stephanie L, Lawrence, Ron M, Brigandi, Richard A, Gomez-delas-Heras, Federico M, Gargallo, Domingo V, Ward, Stephen A
Published in Journal of medicinal chemistry (12.03.2009)
Published in Journal of medicinal chemistry (12.03.2009)
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Journal Article
An Asymmetric Nitro-Mannich Reaction Applicable to Alkyl, Aryl, and Heterocyclic Imines
Anderson, James C, Howell, Gareth P, Lawrence, Ron M, Wilson, Claire S
Published in Journal of organic chemistry (08.07.2005)
Published in Journal of organic chemistry (08.07.2005)
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Journal Article
Cyclic Sulfamidates as Vehicles for the Synthesis of Substituted Lactams
Bower, John F, Švenda, Jakub, Williams, Andrew J, Charmant, Jonathan P. H, Lawrence, Ron M, Szeto, Peter, Gallagher, Timothy
Published in Organic letters (09.12.2004)
Published in Organic letters (09.12.2004)
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Journal Article
Reactivity of cyclic sulfamidates towards phosphonate-stabilised enolates: synthesis and applications of alpha-phosphono lactams
Bower, John F., Williams, Andrew J., Woodward, Hannah L., Szeto, Peter, Lawrence, Ron M., Gallagher, Timothy
Published in Organic & biomolecular chemistry (01.01.2007)
Published in Organic & biomolecular chemistry (01.01.2007)
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Journal Article
1,2-Cyclic Sulfamidates as Versatile Precursors to Thiomorpholines and Piperazines
Williams, Andrew J, Chakthong, Suda, Gray, Diane, Lawrence, Ron M, Gallagher, Timothy
Published in Organic letters (20.03.2003)
Published in Organic letters (20.03.2003)
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Journal Article
Development of a Scalable Synthetic Route to GSK369796 (N-tert-Butyl Isoquine), a Novel 4-Aminoquinoline Antimalarial Drug
Lawrence, Ron M, Dennis, Katherine C, O’Neill, Paul M, Hahn, Dirk Uwe, Roeder, Michael, Struppe, Cornelia
Published in Organic process research & development (01.03.2008)
Published in Organic process research & development (01.03.2008)
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Journal Article
Reactivity of cyclic sulfamidates towards sulfur-stabilised enolates. Stereocontrolled synthesis of functionalised lactams
Bower, JF, Chakthong, S, Svenda, J, Williams, AJ, Lawrence, RM, Szeto, P, Gallagher, T
Published in Organic & biomolecular chemistry (01.01.2006)
Published in Organic & biomolecular chemistry (01.01.2006)
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Journal Article
A practical, two-stage preparation of benzyl (3 R)-3-amino-2-oxo-1-pyrrolidinecarboxylate (2 S,3 S)-2,3-bis[(4-methylbenzoyl)oxy]butanediote (2:1)
Barrett, Roger, Caine, Darren M, Cardwell, Kevin S, Cooke, Jason W.B, Lawrence, Ron M, Scott, Peter, Sjolin, Åsa
Published in Tetrahedron: asymmetry (01.11.2003)
Published in Tetrahedron: asymmetry (01.11.2003)
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