810 NX-1607, a small molecule inhibitor of CBL-B, enhances anti-PD-1-mediated tumor growth inhibition by reshaping intratumoral innate and adaptive immune response
Gallotta, Marilena, Romo, Jose Gomez, Ranucci, Serena, Lee, Ernestine, Borodovsky, Alexandra, Hansen, Gwenn M, Sands, Arthur T, Rountree, Ryan, Guiducci, Cristiana
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
Get full text
Journal Article
Intralesional SD-101 in Combination with Pembrolizumab in Anti-PD-1 Treatment-Naïve Head and Neck Squamous Cell Carcinoma: Results from a Multicenter, Phase II Trial
Cohen, Ezra E W, Nabell, Lisle, Wong, Deborah J, Day, Terry, Daniels, Gregory A, Milhem, Mohammed, Deva, Sanjeev, Jameson, Michael, Guntinas-Lichius, Orlando, Almubarak, Mohammed, Strother, Matthew, Whitman, Eric, Chisamore, Michael, Obiozor, Cynthia, Bagulho, Teresa, Gomez-Romo, Jose, Guiducci, Cristiana, Janssen, Robert, Gamelin, Erick, Algazi, Alain P
Published in Clinical cancer research (15.03.2022)
Published in Clinical cancer research (15.03.2022)
Get full text
Journal Article
Abstract 1595: Small molecule inhibition of the ubiquitin ligase CBL-B results in potent T and NK cell mediated anti-tumor response
Rountree, Ryan, Cohen, Frederick, Tenn-McClellan, Austin, Borodovsky, Alexandra, Gallotta, Marilena, Stokes, Jennifer, Romo, Jose Gomez, Karim, Chris, Hansen, Gwenn M., Guiducci, Cristiana, Sands, Arthur, Gosling, Jennifa
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Get full text
Journal Article
Abstract 573: Ex-vivo inhibition of CBL-B with a novel small molecule inhibitor, NX-0255, enhances persistence and anti-tumor activity of adoptively transferred CD8+ T cells in mouse tumor models
Gallotta, Marilena, Romo, Jose Gomez, Borodovsky, Alexandra, Tenn-McClellan, Austin, Stokes, Jennifer, Gosling, Jennifa, Hansen, Gwenn M., Sands, Arthur, Rountree, Ryan, Guiducci, Cristiana
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article