GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage
Callender, Lauren A., Schroth, Johannes, Carroll, Elizabeth C., Garrod-Ketchley, Conor, Romano, Lisa E. L., Hendy, Eleanor, Kelly, Audrey, Lavender, Paul, Akbar, Arne N., Chapple, J. Paul, Henson, Sian M.
Published in Nature communications (07.06.2021)
Published in Nature communications (07.06.2021)
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Journal Article
AlphaFold predicted structure of the Hsp90-like domains of the neurodegeneration linked protein sacsin reveals key residues for ATPase activity
Perna, Laura, Castelli, Matteo, Frasnetti, Elena, Romano, Lisa E L, Colombo, Giorgio, Prodromou, Chrisostomos, Chapple, J Paul
Published in Frontiers in molecular biosciences (13.01.2023)
Published in Frontiers in molecular biosciences (13.01.2023)
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Journal Article
Altered organization of the intermediate filament cytoskeleton and relocalization of proteostasis modulators in cells lacking the ataxia protein sacsin
Duncan, Emma J, Larivière, Roxanne, Bradshaw, Teisha Y, Longo, Fabiana, Sgarioto, Nicolas, Hayes, Matthew J, Romano, Lisa E L, Nethisinghe, Suran, Giunti, Paola, Bruntraeger, Michaela B, Durham, Heather D, Brais, Bernard, Maltecca, Francesca, Gentil, Benoit J, Chapple, J Paul
Published in Human molecular genetics (15.08.2017)
Published in Human molecular genetics (15.08.2017)
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Journal Article
Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response
Desai, Radha, East, Daniel A, Hardy, Liana, Faccenda, Danilo, Rigon, Manuel, Crosby, James, Alvarez, María Soledad, Singh, Aarti, Mainenti, Marta, Hussey, Laura Kuhlman, Bentham, Robert, Szabadkai, Gyorgy, Zappulli, Valentina, Dhoot, Gurtej K, Romano, Lisa E, Xia, Dong, Coppens, Isabelle, Hamacher-Brady, Anne, Chapple, J Paul, Abeti, Rosella, Fleck, Roland A, Vizcay-Barrena, Gema, Smith, Kenneth, Campanella, Michelangelo
Published in Science advances (01.12.2020)
Published in Science advances (01.12.2020)
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A reduction in Drp1-mediated fission compromises mitochondrial health in autosomal recessive spastic ataxia of Charlevoix Saguenay
Bradshaw, Teisha Y, Romano, Lisa E L, Duncan, Emma J, Nethisinghe, Suran, Abeti, Rosella, Michael, Gregory J, Giunti, Paola, Vermeer, Sascha, Chapple, J Paul
Published in Human molecular genetics (01.08.2016)
Published in Human molecular genetics (01.08.2016)
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Journal Article
Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization
Romano, Lisa E L, Aw, Wen Yih, Hixson, Kathryn M, Novoselova, Tatiana V, Havener, Tammy M, Howell, Stefanie, Taylor-Blake, Bonnie, Hall, Charlotte L, Xing, Lei, Beri, Josh, Nethisinghe, Suran, Perna, Laura, Hatimy, Abubakar, Altadonna, Ginevra Chioccioli, Graves, Lee M, Herring, Laura E, Hickey, Anthony J, Thalassinos, Konstantinos, Chapple, J Paul, Wolter, Justin M
Published in Cell reports (Cambridge) (01.11.2022)
Published in Cell reports (Cambridge) (01.11.2022)
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Journal Article
Oncometabolite induced primary cilia loss in pheochromocytoma
O’Toole, Samuel M, Watson, David S, Novoselova, Tatiana V, Romano, Lisa E L, King, Peter J, Bradshaw, Teisha Y, Thompson, Clare L, Knight, Martin M, Sharp, Tyson V, Barnes, Michael R, Srirangalingam, Umasuthan, Drake, William M, Chapple, J Paul
Published in Endocrine-related cancer (01.01.2019)
Published in Endocrine-related cancer (01.01.2019)
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CCG•CGG interruptions in high‐penetrance SCA8 families increase RAN translation and protein toxicity
Perez, Barbara A, Shorrock, Hannah K, Banez‐Coronel, Monica, Zu, Tao, Romano, Lisa EL, Laboissonniere, Lauren A, Reid, Tammy, Ikeda, Yoshio, Reddy, Kaalak, Gomez, Christopher M, Bird, Thomas, Ashizawa, Tetsuo, Schut, Lawrence J, Brusco, Alfredo, Berglund, J Andrew, Hasholt, Lis F, Nielsen, Jorgen E, Subramony, SH, Ranum, Laura PW
Published in EMBO molecular medicine (08.11.2021)
Published in EMBO molecular medicine (08.11.2021)
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Journal Article
GATA3 controls mitochondrial biogenesis in primary human CD4+ T cells during DNA damage
Callender, Lauren A, Schroth, Johannes, Carroll, Elizabeth C, Romano, Lisa E L, Hendy, Eleanor, Kelly, Audrey, Lavender, Paul, Akbar, Arne N, Chapple, J Paul, Henson, Sian M
Published in bioRxiv (15.05.2020)
Published in bioRxiv (15.05.2020)
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Paper
Mitochondria form contact sites with the nucleus to couple pro-survival retrograde response
Desai, Radha, East, Daniel A, Hardy, Liana, Rigon, Manuel, Faccenda, Danilo, Alvarex, Maria Soledad, Singh, Aarti, Mainenti, Marta, Laura Kuhlman Hussey, Bentham, Robert, Szabadkai, Gyorgy, Zappulli, Valentina, Dhoot, Gurtej, Romano, Lisa E, Xia Dong, Coppens, Isabelle, Hamacher-Brady, Anne, Chapple, Paul, Fleck, Roland A, Vizcay-Barrena, Gema, Abeti, Rosella, Smith, Kenneth, Campanella, Michelangelo
Published in bioRxiv (07.05.2020)
Published in bioRxiv (07.05.2020)
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Paper