Search Results - "Romanelli, Angela" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

The Antitumor Activity of IMGN529, a CD37-Targeting Antibody-Drug Conjugate, Is Potentiated by Rituximab in Non-Hodgkin Lymphoma Models

The Antitumor Activity of IMGN529, a CD37-Targeting Antibody-Drug Conjugate, Is Potentiated by Rituximab in Non-Hodgkin Lymphoma Models

by Hicks, Stuart W., Lai, Katharine C., Gavrilescu, L. Cristina, Yi, Yong, Sikka, Surina, Shah, Prerak, Kelly, Meghan E., Lee, Jenny, Lanieri, Leanne, Ponte, Jose F., Sloss, Callum M., Romanelli, Angela
Published in Neoplasia (New York, N.Y.) (01.09.2017)

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Journal Article

p70 S6 Kinase Is Regulated by Protein Kinase Cζ and Participates in a Phosphoinositide 3-Kinase-Regulated Signalling Complex

p70 S6 Kinase Is Regulated by Protein Kinase Cζ and Participates in a Phosphoinositide 3-Kinase-Regulated Signalling Complex

by Romanelli, Angela, Martin, Kathleen A., Toker, Alex, Blenis, John
Published in Molecular and Cellular Biology (01.04.1999)

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Journal Article

Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK

Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK

by Richards, Stephanie A., Fu, Joyce, Romanelli, Angela, Shimamura, Akiko, Blenis, John
Published in Current biology (12.08.1999)

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Regulation of Ribosomal S6 Kinase 2 by Effectors of the Phosphoinositide 3-Kinase Pathway

Regulation of Ribosomal S6 Kinase 2 by Effectors of the Phosphoinositide 3-Kinase Pathway

by Martin, Kathleen A., Schalm, Stefanie S., Richardson, Celeste, Romanelli, Angela, Keon, Kristen L., Blenis, John
Published in The Journal of biological chemistry (16.03.2001)

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Journal Article

Ribosomal S6 Kinase 2 Inhibition by a Potent C-terminal Repressor Domain Is Relieved by Mitogen-activated Protein-Extracellular Signal-regulated Kinase Kinase-regulated Phosphorylation

Ribosomal S6 Kinase 2 Inhibition by a Potent C-terminal Repressor Domain Is Relieved by Mitogen-activated Protein-Extracellular Signal-regulated Kinase Kinase-regulated Phosphorylation

by Martin, Kathleen A., Schalm, Stefanie S., Romanelli, Angela, Keon, Kristen L., Blenis, John
Published in The Journal of biological chemistry (16.03.2001)

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Journal Article

Characterization of Phosphatidylinositol 3-Kinase-dependent Phosphorylation of the Hydrophobic Motif Site Thr389 in p70 S6 Kinase 1

Characterization of Phosphatidylinositol 3-Kinase-dependent Phosphorylation of the Hydrophobic Motif Site Thr389 in p70 S6 Kinase 1

by Romanelli, Angela, Dreisbach, Valley C., Blenis, John
Published in The Journal of biological chemistry (25.10.2002)

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The Activated Glucocorticoid Receptor Modulates Presumptive Autoregulation of Ribosomal Protein S6 Protein Kinase, p70 S6K

The Activated Glucocorticoid Receptor Modulates Presumptive Autoregulation of Ribosomal Protein S6 Protein Kinase, p70 S6K

by Shah, O. Jameel, Iniguez-Lluhi, Jorge A., Romanelli, Angela, Kimball, Scot R., Jefferson, Leonard S.
Published in The Journal of biological chemistry (25.01.2002)

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Journal Article

Combining IMGN632, a Novel CD123-Targeting Antibody Drug Conjugate with Azacitidine and Venetoclax Facilitates Apoptosis in Vitro and Prolongs Survival In Vivo in AML Models

Combining IMGN632, a Novel CD123-Targeting Antibody Drug Conjugate with Azacitidine and Venetoclax Facilitates Apoptosis in Vitro and Prolongs Survival In Vivo in AML Models

by Kuruvilla, Vinitha Mary, Zhang, Qi, Daver, Naval, Watkins, Krystal, Sloss, Callum M, Zweidler-McKay, Patrick A, Romanelli, Angela, Konopleva, Marina
Published in Blood (05.11.2020)

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IMGN632, a CD123-Alkylating ADC Bearing a DNA-Alkylating IGN Payload, Combines Effectively with Azacitidine and Venetoclax In Vivo, Prolonging Survival in Preclinical Models of Human Acute Myeloid Leukemia (AML)

IMGN632, a CD123-Alkylating ADC Bearing a DNA-Alkylating IGN Payload, Combines Effectively with Azacitidine and Venetoclax In Vivo, Prolonging Survival in Preclinical Models of Human Acute Myeloid Leukemia (AML)

by Kuruvilla, Vinitha Mary, McCarthy, Rebecca, Zhang, Qi, Sloss, Callum M., Zweidler-McKay, Patrick A., Romanelli, Angela, Adams, Sharlene, Konopleva, Marina Y
Published in Blood (13.11.2019)

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Journal Article

IMGN779, a Next Generation CD33-Targeting ADC, Combines Effectively with Cytarabine in Acute Myeloid Leukemia (AML) Preclinical Models, Resulting in Increased DNA Damage Response, Cell Cycle Arrest and Apoptosis In Vitro and Prolonged Survival In Vivo

IMGN779, a Next Generation CD33-Targeting ADC, Combines Effectively with Cytarabine in Acute Myeloid Leukemia (AML) Preclinical Models, Resulting in Increased DNA Damage Response, Cell Cycle Arrest and Apoptosis In Vitro and Prolonged Survival In Vivo

by Adams, Sharlene, Kelly, Meghan, McCarthy, Rebecca, Wilhelm, Alan, Watkins, Krystal, Lanieri, Leanne, Sloss, Callum M., Romanelli, Angela
Published in Blood (08.12.2017)

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Abstract 45: In vitro and in vivo activity of a novel c-Met-targeting antibody-drug conjugate using a DNA-alkylating, indolinobenzodiazepine payload

Abstract 45: In vitro and in vivo activity of a novel c-Met-targeting antibody-drug conjugate using a DNA-alkylating, indolinobenzodiazepine payload

by Lai, Katharine C., Muvaffak, Asli, Li, Min, Themeles, Marian, Sikka, Surina, Donahue, Kerry, Hicks, Stuart W., Romanelli, Angela, Chittenden, Thomas
Published in Cancer research (Chicago, Ill.) (01.07.2017)

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Abstract 1073: Increased internalization and processing of the CD37-targeting antibody-drug conjugate, naratuximab emtansine (IMGN529), in the presence of rituximab leads to enhanced potency in diffuse large B-cell lymphoma models

Abstract 1073: Increased internalization and processing of the CD37-targeting antibody-drug conjugate, naratuximab emtansine (IMGN529), in the presence of rituximab leads to enhanced potency in diffuse large B-cell lymphoma models

by Hicks, Stuart W., Lai, Katharine C., Yi, Yong, Shah, Prerak, Gavrilescu, Cristina L., Ponte, Joe, Sloss, Callum M., Romanelli, Angela
Published in Cancer research (Chicago, Ill.) (01.07.2017)

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항-CD123 면역접합체를 사용하는 치료 방법

항-CD123 면역접합체를 사용하는 치료 방법

by ZWEIDLER MCKAY PATRICK, SLOSS CALLUM, CULM MERDEK KERRY, ROMANELLI ANGELA
Year of Publication 13.07.2021

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Patent

AML-367: IMGN632, a CD123-Targeting ADC Bearing a DNA-Alkylating IGN Payload, Combines Effectively as a Triplet Regimen with Azacitidine and Venetoclax In Vivo, Prolonging Survival in Preclinical Models of Human Acute Myeloid Leukemia (AML)

AML-367: IMGN632, a CD123-Targeting ADC Bearing a DNA-Alkylating IGN Payload, Combines Effectively as a Triplet Regimen with Azacitidine and Venetoclax In Vivo, Prolonging Survival in Preclinical Models of Human Acute Myeloid Leukemia (AML)

by Kuruvilla, Vinitha, McCarthy, Rebecca, Zhang, Qi, Watkins, Krystal, Adams, Sharlene, Sloss, Callum, Zweidler-McKay, Patrick, Romanelli, Angela, Konopleva, Marina
Published in Clinical lymphoma, myeloma and leukemia (01.09.2020)

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Journal Article

Clinical factors that affect walking level and performance in chronic spinal cord lesion patients

Clinical factors that affect walking level and performance in chronic spinal cord lesion patients

by Scivoletto, Giorgio, Romanelli, Angela, Mariotti, Andrea, Marinucci, Daniele, Tamburella, Federica, Mammone, Alessia, Cosentino, Elena, Sterzi, Silvia, Molinari, Marco
Published in Spine (Philadelphia, Pa. 1976) (01.02.2008)

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IMGN779, a CD33-Targeted Antibody-Drug Conjugate (ADC) with a Novel DNA-Alkylating Effector Molecule, Induces DNA Damage, Cell Cycle Arrest, and Apoptosis in AML Cells

IMGN779, a CD33-Targeted Antibody-Drug Conjugate (ADC) with a Novel DNA-Alkylating Effector Molecule, Induces DNA Damage, Cell Cycle Arrest, and Apoptosis in AML Cells

by Krystal, Watkins M, Walker, Russell, Fishkin, Nathan, Audette, Charlene, Kovtun, Yelena, Romanelli, Angela
Published in Blood (03.12.2015)

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$Coltuximab Ravtansine (SAR3419) Demonstrates Enhanced Activity in Combination with Bendamustine, Gemcitabine and Novel Targeted Agents Such As PI3K Inhibitors in Pre-Clinical Models of Relapsed and/or Refractory Non-Hodgkins Lymphoma (NHL)$

Coltuximab Ravtansine (SAR3419) Demonstrates Enhanced Activity in Combination with Bendamustine, Gemcitabine and Novel Targeted Agents Such As PI3K Inhibitors in Pre-Clinical Models of Relapsed and/or Refractory Non-Hodgkins Lymphoma (NHL)

by Sloss, Callum M, O'Callaghan, Katie, Deckert, Jutta, Tsui, Jenny, Lanieri, Leanne, Romanelli, Angela
Published in Blood (03.12.2015)

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Abstract 3400A: Development and application of an immunohistochemistry-based clinical assay for evaluating Folate Receptor Alpha (FRα) expression in a phase I clinical trial of IMGN853

Abstract 3400A: Development and application of an immunohistochemistry-based clinical assay for evaluating Folate Receptor Alpha (FRα) expression in a phase I clinical trial of IMGN853

by Zhao, Jianhua, LaBelle, Alyssa, Ab, Olga, Acosta, Krista, Yates, Al, Zhou, Yinghui, Romanelli, Angela
Published in Cancer research (Chicago, Ill.) (01.08.2015)

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Abstract 4765: Drug synergies observed for antibody and toxin components of SAR3419 ADC contribute to overall conjugate efficacy and can be combination drug or tumor cell line dependent

Abstract 4765: Drug synergies observed for antibody and toxin components of SAR3419 ADC contribute to overall conjugate efficacy and can be combination drug or tumor cell line dependent

by Rickles, Richard J., Giordano, Thomas P., Cotard, Shakira F., Grenier, Jill M., Romanelli, Angela, Cai, Ti
Published in Cancer research (Chicago, Ill.) (01.10.2014)

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Journal Article

Cardiovascular effects of troglitazone

Cardiovascular effects of troglitazone

by Umland, E M, Romanelli, A M
Published in The Annals of pharmacotherapy (01.02.1999)

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