CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer
Xiang, Jingyu, Hurchla, Michelle A, Fontana, Francesca, Su, Xinming, Amend, Sarah R, Esser, Alison K, Douglas, Garry J, Mudalagiriyappa, Chidananda, Luker, Kathryn E, Pluard, Timothy, Ademuyiwa, Foluso O, Romagnoli, Barbara, Tuffin, Gérald, Chevalier, Eric, Luker, Gary D, Bauer, Michael, Zimmermann, Johann, Aft, Rebecca L, Dembowsky, Klaus, Weilbaecher, Katherine N
Published in Molecular cancer therapeutics (01.11.2015)
Published in Molecular cancer therapeutics (01.11.2015)
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Journal Article
In silico identification of glycosylphosphatidylinositol-anchored proteins in Paracoccidioides spp
Gonçales, Relber A, Salamanca, Ayda Lm, Júnior, Luiz Rb, E Silva, Kleber Sf, de Vasconcelos, Elton Jr, Dos Reis, Thaila F, Castro, Ricardo C, C Ruy, Patrícia de, Romagnoli, Bárbara, Ruiz, Jerônimo, Pereira, Maristela, de A Soares, Célia M, Coelho, Paulo Sr
Published in Future microbiology (01.05.2021)
Published in Future microbiology (01.05.2021)
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Journal Article
Structure-Based Design of Selective and Potent G Quadruplex-Mediated Telomerase Inhibitors
Read, Martin, Harrison, R. John, Romagnoli, Barbara, Tanious, Farial A., Gowan, Sharon H., Reszka, Anthony P., Wilson, W. David, Kelland, Lloyd R., Neidle, Stephen
Published in Proceedings of the National Academy of Sciences - PNAS (24.04.2001)
Published in Proceedings of the National Academy of Sciences - PNAS (24.04.2001)
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Journal Article
Anti-HIV Activity and Resistance Profile of the CXC Chemokine Receptor 4 Antagonist POL3026
Moncunill, Gemma, Armand-Ugón, Mercedes, Clotet-Codina, Imma, Pauls, Eduardo, Ballana, Ester, Llano, Anuska, Romagnoli, Barbara, Vrijbloed, Jan W, Gombert, Frank O, Clotet, Bonaventura, De Marco, Steve, Esté, José A
Published in Molecular pharmacology (01.04.2008)
Published in Molecular pharmacology (01.04.2008)
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Journal Article
One-pot synthesis of multivalent arrays of mannose mono- and disaccharides
Hayes, Wayne, Osborn, Helen M.I, Osborne, Sadie D, Rastall, Robert A, Romagnoli, Barbara
Published in Tetrahedron (29.09.2003)
Published in Tetrahedron (29.09.2003)
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Journal Article
Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding
Harrison, R. John, Reszka, Anthony P., Haider, Shozeb M., Romagnoli, Barbara, Morrell, James, Read, Martin A., Gowan, Sharon M., Incles, Christopher M., Kelland, Lloyd R., Neidle, Stephen
Published in Bioorganic & medicinal chemistry letters (06.12.2004)
Published in Bioorganic & medicinal chemistry letters (06.12.2004)
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Journal Article
Abstract 3965: Circulating levels of IFN gammaand neutrophil counts in breast cancer patients who received balixafortide and eribulin combination therapy
Zimmermann, Johann, Douglas, Garry, Romagnoli, Barbara, Barker, Debra, Obrecht, Daniel
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Balixafortide plus eribulin in HER2-negative metastatic breast cancer: a phase 1, single-arm, dose-escalation trial
Pernas, Sonia, Martin, Miguel, Kaufman, Peter A, Gil-Martin, Marta, Gomez Pardo, Patricia, Lopez-Tarruella, Sara, Manso, Luis, Ciruelos, Eva, Perez-Fidalgo, Jose Alejandro, Hernando, Cristina, Ademuyiwa, Foluso O, Weilbaecher, Katherine, Mayer, Ingrid, Pluard, Timothy J, Martinez Garcia, Maria, Vahdat, Linda, Perez-Garcia, Jose, Wach, Achim, Barker, Debra, Fung, Samson, Romagnoli, Barbara, Cortes, Javier
Published in The lancet oncology (01.06.2018)
Published in The lancet oncology (01.06.2018)
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Simultaneous determination of deoxynivalenol, zearalenone, T-2 and HT-2 toxins in breakfast cereals and baby food by high-performance liquid chromatography and tandem mass spectrometry
Romagnoli, Barbara, Ferrari, Maria, Bergamini, Cecilia
Published in Journal of mass spectrometry (01.09.2010)
Published in Journal of mass spectrometry (01.09.2010)
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Journal Article
Conference Proceeding
Discovery of Highly Potent and Selective CXCR4 Inhibitors Using Protein Epitope Mimetics (PEM) Technology
Alexander Lederer, John A. Robinson, Kerstin Moehle, Thomas Klimkait, François Hamy, Vincent Brondani, Sergio Lociuro, Jean-Pierre Obrecht, Jan Willem Vrijbloed, Christian Ludin, Frank O. Gombert, Federico Brianza, Jürg Zumbrunn, Reshmi Mukherjee, Barbara Romagnoli, Heiko Henze, Steven J. DeMarco, Daniel Obrecht
Published in Chimia (25.04.2007)
Published in Chimia (25.04.2007)
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Journal Article
Abstract OT1-08-06: International, phase 3 trial: Balixafortide (a CXCR4 antagonist) + eribulin versus eribulin alone in patients with HER2 negative, locally recurrent or metastatic breast cancer (FORTRESS) international, phase 3 trial: Balixafortide (a CXCR4 antagonist) + eribulin versus eribulin alone in patients with HER2 negative, locally recurrent or metastatic breast cancer (FORTRESS)
Kaufmann, Peter, Cortes, Javier, Martin, Miguel, Mayer, Ingrid, Vahdat, Linda, Pernas, Sonia, Schmid, Peter, McArthur, Heather, Dent, Rebecca, Rugo, Hope, Barrios, Carlos, Barker, Debra, Romagnoli, Barbara, Bobirca, Alexandra
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Journal Article
Multifaceted C-X-C Chemokine Receptor 4 (CXCR4) Inhibition Interferes with Anti–Vascular Endothelial Growth Factor Therapy–Induced Glioma Dissemination
Gagner, Jean-Pierre, Sarfraz, Yasmeen, Ortenzi, Valerio, Alotaibi, Fawaz M., Chiriboga, Luis A., Tayyib, Awab T., Douglas, Garry J., Chevalier, Eric, Romagnoli, Barbara, Tuffin, Gérald, Schmitt, Michel, Lemercier, Guillaume, Dembowsky, Klaus, Zagzag, David
Published in The American journal of pathology (01.09.2017)
Published in The American journal of pathology (01.09.2017)
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Journal Article
Mobilization of hematopoietic stem cells with the novel CXCR4 antagonist POL6326 (balixafortide) in healthy volunteers-results of a dose escalation trial
Karpova, Darja, Bräuninger, Susanne, Wiercinska, Eliza, Krämer, Ariane, Stock, Belinda, Graff, Jochen, Martin, Hans, Wach, Achim, Escot, Christophe, Douglas, Garry, Romagnoli, Barbara, Chevalier, Eric, Dembowski, Klaus, Hooftman, Leon, Bonig, Halvard
Published in Journal of translational medicine (03.01.2017)
Published in Journal of translational medicine (03.01.2017)
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Journal Article
CXCR7-dependent angiogenic mononuclear cell trafficking regulates tumor progression in multiple myeloma
Azab, Abdel Kareem, Sahin, Ilyas, Azab, Feda, Moschetta, Michele, Mishima, Yuji, Burwick, Nicholas, Zimmermann, Johann, Romagnoli, Barbara, Patel, Kalpana, Chevalier, Eric, Roccaro, Aldo M., Ghobrial, Irene M.
Published in Blood (18.09.2014)
Published in Blood (18.09.2014)
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Journal Article
Balixafortide (a CXCR4 antagonist) + eribulin in HER2-negative metastatic breast cancer (MBC): Survival outcomes of the phase I trial
Kaufman, Peter A., Pernas Simon, Sonia, Martin, Miguel, Gil-Martin, Marta, Gomez Pardo, Patricia, Lopez-Tarruella, Sara, Manso, Luis, Ciruelos, Eva, Perez-Fidalgo, Jose Alejandro, Hernando, Cristina, Ademuyiwa, Foluso Olabisi, Weilbaecher, Katherine N., Mayer, Ingrid A., Pluard, Timothy J., Martinez Garcia, Maria, Vahdat, Linda T., Barker, Debra, Romagnoli, Barbara, Cortes, Javier
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Journal Article
POL5551, a novel and potent CXCR4 antagonist, enhances sensitivity to chemotherapy in pediatric ALL
Sison, Edward Allan R, Magoon, Daniel, Li, Li, Annesley, Colleen E, Romagnoli, Barbara, Douglas, Garry J, Tuffin, Gerald, Zimmermann, Johann, Brown, Patrick
Published in Oncotarget (13.10.2015)
Published in Oncotarget (13.10.2015)
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Journal Article
POL5551, a Novel and Potent CXCR4 Antagonist, Enhances Sensitivity to Chemotherapy in an in Vivo Model of High-Risk (HR) Pediatric Acute Lymphoblastic Leukemia (ALL)
Sison, Edward Allan R., Magoon, Daniel, Li, Li, Romagnoli, Barbara, Douglas, Garry, Tuffin, Gerald, Zimmermann, Johann, Brown, Patrick
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Potent Stem Cell Mobilization with the Novel CXCR4 Antagonist POL6326 - Results of a Phase IIa Dose Escalation Study in Comparison to G-CSF
Karpova, Darja, Brauninger, Susanne, Wiercinska, Eliza, Kraemer, Ariane, Stock, Belinda, Graff, Jochen, Escot, Christophe, Douglas, Garry, Romagnoli, Barbara, Chevalier, Eric, Dembowsky, Klaus, Hooftman, Leon, Bonig, Halvard
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma
Barone, Amy, Sengupta, Rajarshi, Warrington, Nicole M, Smith, Erin, Wen, Patrick Y, Brekken, Rolf A, Romagnoli, Barbara, Douglas, Garry, Chevalier, Eric, Bauer, Michael P, Dembowsky, Klaus, Piwnica-Worms, David, Rubin, Joshua B
Published in Oncotarget (30.10.2014)
Published in Oncotarget (30.10.2014)
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Journal Article
Dose escalation of POL6326 in combination with eribulin in HER2-negative relapsed metastatic breast cancer (mBCa) patients (pts)
Pernas Simon, Sonia, Cortes, Javier, Ademuyiwa, Foluso Olabisi, Lopez-Tarruella, Sara, Manso, Luis, Kaufman, Peter, Hooftman, Leon W., Romagnoli, Barbara, Perez-Fidalgo, Jose Alejandro, Pluard, Timothy J., Weilbaecher, Katherine N., Gomez Pardo, Patricia
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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