Structure-Based Design of Spiro-oxindoles as Potent, Specific Small-Molecule Inhibitors of the MDM2−p53 Interaction
Ding, Ke, Lu, Yipin, Nikolovska-Coleska, Zaneta, Wang, Guoping, Qiu, Su, Shangary, Sanjeev, Gao, Wei, Qin, Dongguang, Stuckey, Jeanne, Krajewski, Krzysztof, Roller, Peter P, Wang, Shaomeng
Published in Journal of medicinal chemistry (15.06.2006)
Published in Journal of medicinal chemistry (15.06.2006)
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Journal Article
Structure-Based Design of Potent Non-Peptide MDM2 Inhibitors
Ding, Ke, Lu, Yipin, Nikolovska-Coleska, Zaneta, Qiu, Su, Ding, Yousong, Gao, Wei, Stuckey, Jeanne, Krajewski, Krzysztof, Roller, Peter P, Tomita, York, Parrish, Damon A, Deschamps, Jeffrey R, Wang, Shaomeng
Published in Journal of the American Chemical Society (27.07.2005)
Published in Journal of the American Chemical Society (27.07.2005)
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Journal Article
Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization
Nikolovska-Coleska, Zaneta, Wang, Renxiao, Fang, Xueliang, Pan, Hongguang, Tomita, York, Li, Peng, Roller, Peter P., Krajewski, Krzysztof, Saito, Naoyuki G., Stuckey, Jeanne A., Wang, Shaomeng
Published in Analytical biochemistry (15.09.2004)
Published in Analytical biochemistry (15.09.2004)
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Journal Article
Discovery of Small-Molecule Inhibitors of Bcl-2 through Structure-Based Computer Screening
Enyedy, Istvan J, Ling, Yan, Nacro, Kassoum, Tomita, York, Wu, Xihan, Cao, Yeyu, Guo, Ribo, Li, Bihua, Zhu, Xiaofeng, Huang, Ying, Long, Ya-Qiu, Roller, Peter P, Yang, Dajun, Wang, Shaomeng
Published in Journal of medicinal chemistry (06.12.2001)
Published in Journal of medicinal chemistry (06.12.2001)
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Journal Article
Structure-Based Design of Potent Small-Molecule Inhibitors of Anti-Apoptotic Bcl-2 Proteins
Wang, Guoping, Nikolovska-Coleska, Zaneta, Yang, Chao-Yie, Wang, Renxiao, Tang, Guozhi, Guo, Jie, Shangary, Sanjeev, Qiu, Su, Gao, Wei, Yang, Dajun, Meagher, Jennifer, Stuckey, Jeanne, Krajewski, Krzysztof, Jiang, Sheng, Roller, Peter P, Abaan, Hatice Ozel, Tomita, York, Wang, Shaomeng
Published in Journal of medicinal chemistry (19.10.2006)
Published in Journal of medicinal chemistry (19.10.2006)
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Journal Article
Discovery of Embelin as a Cell-Permeable, Small-Molecular Weight Inhibitor of XIAP through Structure-Based Computational Screening of a Traditional Herbal Medicine Three-Dimensional Structure Database
Nikolovska-Coleska, Zaneta, Xu, Liang, Hu, Zengjian, Tomita, York, Li, Peng, Roller, Peter P, Wang, Renxiao, Fang, Xueliang, Guo, Ribo, Zhang, Manchao, Lippman, Marc E, Yang, Dajun, Wang, Shaomeng
Published in Journal of medicinal chemistry (06.05.2004)
Published in Journal of medicinal chemistry (06.05.2004)
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Structure-Based Design, Synthesis, and Evaluation of Conformationally Constrained Mimetics of the Second Mitochondria-Derived Activator of Caspase That Target the X-Linked Inhibitor of Apoptosis Protein/Caspase-9 Interaction Site
Sun, Haiying, Nikolovska-Coleska, Zaneta, Yang, Chao-Yie, Xu, Liang, Tomita, York, Krajewski, Krzysztof, Roller, Peter P, Wang, Shaomeng
Published in Journal of medicinal chemistry (12.08.2004)
Published in Journal of medicinal chemistry (12.08.2004)
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Journal Article
Conformational transitions, dissociation, and unfolding of scrapie amyloid (prion) protein
Safar, J, Roller, P.P, Gajdusek, D.C, Gibbs, C.J. Jr
Published in The Journal of biological chemistry (25.09.1993)
Published in The Journal of biological chemistry (25.09.1993)
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Journal Article
Discovery of a Novel Nonphosphorylated Pentapeptide Motif Displaying High Affinity for Grb2-SH2 Domain by the Utilization of 3‘-Substituted Tyrosine Derivatives
Song, Yan-Li, Peach, Megan L, Roller, Peter P, Qiu, Su, Wang, Shaomeng, Long, Ya-Qiu
Published in Journal of medicinal chemistry (09.03.2006)
Published in Journal of medicinal chemistry (09.03.2006)
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Journal Article
Structure-Based Design of Potent, Conformationally Constrained Smac Mimetics
Sun, Haiying, Nikolovska-Coleska, Zaneta, Yang, Chao-Yie, Xu, Liang, Liu, Meilan, Tomita, York, Pan, Hongguang, Yoshioka, Yoshiko, Krajewski, Krzysztof, Roller, Peter P, Wang, Shaomeng
Published in Journal of the American Chemical Society (29.12.2004)
Published in Journal of the American Chemical Society (29.12.2004)
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Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells
Zhang, Manchao, Liu, Hongpeng, Guo, Ribo, Ling, Yan, Wu, Xiaojin, Li, Bihua, Roller, Peter P., Wang, Shaomeng, Yang, Dajun
Published in Biochemical pharmacology (01.07.2003)
Published in Biochemical pharmacology (01.07.2003)
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Journal Article
The GADD45 Inhibition of Cdc2 Kinase Correlates with GADD45-mediated Growth Suppression
Jin, Shunqian, Antinore, Michael J., Lung, Feng-Di T., Dong, Xin, Zhao, Hongcheng, Fan, Feiyue, Colchagie, Amy B., Blanck, Patricia, Roller, Peter P., Fornace, Albert J., Zhan, Qimin
Published in The Journal of biological chemistry (02.06.2000)
Published in The Journal of biological chemistry (02.06.2000)
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Journal Article
Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction
S Xiao, D W Rose, T Sasaoka, H Maegawa, T R Burke, Jr, P P Roller, S E Shoelson, J M Olefsky
Published in The Journal of biological chemistry (19.08.1994)
Published in The Journal of biological chemistry (19.08.1994)
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Journal Article
Oligomerization of Human Gadd45a Protein
Kovalsky, Oleg, Lung, Feng-Di T., Roller, Peter P., Fornace, Albert J.
Published in The Journal of biological chemistry (19.10.2001)
Published in The Journal of biological chemistry (19.10.2001)
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Journal Article
Identification of Novel Non-phosphorylated Ligands, Which Bind Selectively to the SH2 Domain of Grb7
Pero, Stephanie C., Oligino, Lyn, Daly, Roger J., Soden, Amy L., Liu, Chen, Roller, Peter P., Li, Peng, Krag, David N.
Published in The Journal of biological chemistry (05.04.2002)
Published in The Journal of biological chemistry (05.04.2002)
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Journal Article
New HIV-1 reverse transcriptase inhibitors based on a tricyclic benzothiophene scaffold: Synthesis, resolution, and inhibitory activity
Krajewski, Krzysztof, Zhang, Yijun, Parrish, Damon, Deschamps, Jeffrey, Roller, Peter P., Pathak, Vinay K.
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
Published in Bioorganic & medicinal chemistry letters (01.06.2006)
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