Keratinocyte growth factor enhances barrier function without altering claudin expression in primary alveolar epithelial cells
LaFemina, Michael J, Rokkam, Deepti, Chandrasena, Anita, Pan, Jue, Bajaj, Anisha, Johnson, Meshell, Frank, James A
Published in American journal of physiology. Lung cellular and molecular physiology (01.12.2010)
Published in American journal of physiology. Lung cellular and molecular physiology (01.12.2010)
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228 Engineered human IL-2/IL-2Rß orthogonal pairs selectively enhance anti-GPC3 CAR T cells in vivo to drive complete responses in solid epithelial tumor models
Aspuria, Paul-Joseph, Semana, Marie, Cheng, Ivan, Ratti, Navneet, Ramadass, Mahalaksmi, Rokkam, Deepti, Ali, Mohammed, Bauer, Michele, Burgess, Ryan, Rosas, Henry, Vivona, Sandro, Zheng, George, Lupardus, Patrick, Oft, Martin
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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1053 Preclinical pharmacodynamic characterization of STK-026: a novel IL-12 partial agonist for cancer with maintained CD8 T cell activity, reduced NK-mediated toxicity and an improved therapeutic window
Koliesnik, Zhenya, Totagrande, Michael, Burgess, Ryan, Tran, Kim Q, Bauer, Michele, Jayaraman, Bharghavi, Buffone, Cindy, Balasubrahmanyam, Priyanka, Emmerich, Jan, Chaturvedi, Deepti, Rokkam, Deepti, Malefyt, Rene De Waal, Greb, Heiko, Ratti, Navneet, Vivona, Sandro, Kastelein, Robert, Lupardus, Patrick, Zuniga, Luis, Rosen, David B, Oft, Martin
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Claudin-18 Deficiency Results in Alveolar Barrier Dysfunction and Impaired Alveologenesis in Mice
LaFemina, Michael J., Sutherland, Katherine M., Bentley, Trevor, Gonzales, Linda W., Allen, Lennell, Chapin, Cheryl J., Rokkam, Deepti, Sweerus, Kelly A., Dobbs, Leland G., Ballard, Philip L., Frank, James A.
Published in American journal of respiratory cell and molecular biology (01.10.2014)
Published in American journal of respiratory cell and molecular biology (01.10.2014)
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Claudin-4 Levels Are Associated with Intact Alveolar Fluid Clearance in Human Lungs
Rokkam, Deepti, LaFemina, Michael J, Lee, Jae Woo, Matthay, Michael A, Frank, James A
Published in The American journal of pathology (01.09.2011)
Published in The American journal of pathology (01.09.2011)
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Claudin-18 deficiency results in alveolar barrier dysfunction and impaired alveologenesis in mice
LaFemina, Michael J, Sutherland, Katherine M, Bentley, Trevor, Gonzales, Linda W, Allen, Lennell, Chapin, Cheryl J, Rokkam, Deepti, Sweerus, Kelly A, Dobbs, Leland G, Ballard, Philip L, Frank, James A
Published in American journal of respiratory cell and molecular biology (01.10.2014)
Published in American journal of respiratory cell and molecular biology (01.10.2014)
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Abstract 1512: OrthoCARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell antitumor efficacy by driving T cell expansion and fitness
Aspuria, Paul-Joseph P., Vivona, Sandro, Bauer, Michele, Semana, Marie, Ratti, Navneet, McCauley, Scott, Riener, Romina, Malefyt, Rene de Waal, Rokkam, Deepti, Emmerich, Jan, Lupardus, Patrick J., Kastelein, Rob A., Oft, Martin
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 1744: STK-012, an alpha/beta selective IL-2 mutein for the activation of the antigen-activated T cells in solid tumor
Emmerich, Jan, Bauer, Michele, Semana, Marie, Jayaraman, Bhargavi, Vivona, Sandro, McCauley, Scott, Riener, Romina, Malefyt, Rene De Waal, Aspuria, Paul-Joseph, Rokkam, Deepti, Lupardus, Patrick, Kastelein, Rob, Oft, Martin
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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OrthoCARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell antitumorefficacy
Aspuria, Paul-Joseph, Bauer, Michael A, vivona, Sandro, de Waal Malefyt, Rene, Kastelein, Rob, Oft, Martin, Emmerich, Jan, Rokkam, Deepti, Kauder, Steven E, McCauley, Scott, Riener, Romina, Verma, Rakesh
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Abstract 3252: Ortho CARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell anti-tumor efficacy and durability of response
Aspuria, Paul-Joseph, Bauer, Michele, Vivona, Sandro, Kauder, Steven E., McCauley, Scott, Riener, Romina, Malefyte, Rene De Waal, Ratti, Navneet, Rokkam, Deepti, Emmerich, Jan, Lupardus, Patrick J., Kastelein, Rob A., Oft, Martin
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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An orthogonal IL-2 and IL-2Rβ system drives persistence and activation of CAR T cells and clearance of bulky lymphoma
Aspuria, Paul-Joseph, Vivona, Sandro, Bauer, Michele, Semana, Marie, Ratti, Navneet, McCauley, Scott, Riener, Romina, de Waal Malefyt, Rene, Rokkam, Deepti, Emmerich, Jan, Kastelein, Rob A, Lupardus, Patrick J, Oft, Martin
Published in Science translational medicine (22.12.2021)
Published in Science translational medicine (22.12.2021)
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IL10 수용체 결합 분자 및 사용 방법
VIVONA SANDRO, LUPARDUS PATRICK J, KASTELEIN ROBERT, RAMADASS MAHALAKSHMI, ROKKAM DEEPTI
Year of Publication 11.05.2023
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Year of Publication 11.05.2023
Patent
Abstract 6312: Orthogonal IL-2/IL-2Rβ signaling selectively enhances and sustains a synthetic effector state via a novel mechanism and outperforms constitutive armoring approaches
Jung, Ethan, Silva, Helena, Semana, Marie, Cheng, Ivan, Singh, Somya, Bauer, Michele, Ali, Mohammed, Rosas, Henry, Burgess, Ryan, Zeng, George, Chang, Woei, Ratti, Navneet, Rokkam, Deepti, Lupardus, Patrick J., Oft, Martin, Aspuria, Paul-Joseph
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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