Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein
Harischandra, Dilshan S, Rokad, Dharmin, Neal, Matthew L, Ghaisas, Shivani, Manne, Sireesha, Sarkar, Souvarish, Panicker, Nikhil, Zenitsky, Gary, Jin, Huajun, Lewis, Mechelle, Huang, Xuemei, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G
Published in Science signaling (12.03.2019)
Published in Science signaling (12.03.2019)
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Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells
Sarkar, Souvarish, Rokad, Dharmin, Malovic, Emir, Luo, Jie, Harischandra, Dilshan S, Jin, Huajun, Anantharam, Vellareddy, Huang, Xuemei, Lewis, Mechelle, Kanthasamy, Arthi, Kanthasamy, Anumantha G
Published in Science signaling (08.01.2019)
Published in Science signaling (08.01.2019)
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Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events
Singh, Neeraj, Lawana, Vivek, Luo, Jie, Phong, Phang, Abdalla, Ahmed, Palanisamy, Bharathi, Rokad, Dharmin, Sarkar, Souvarish, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Anumantha G., Kanthasamy, Arthi
Published in Neurobiology of disease (01.09.2018)
Published in Neurobiology of disease (01.09.2018)
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Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease
Gordon, Richard, Singh, Neeraj, Lawana, Vivek, Ghosh, Anamitra, Harischandra, Dilshan S, Jin, Huajun, Hogan, Colleen, Sarkar, Souvarish, Rokad, Dharmin, Panicker, Nikhil, Anantharam, Vellareddy, Kanthasamy, Anumantha G, Kanthasamy, Arthi
Published in Neurobiology of disease (01.09.2016)
Published in Neurobiology of disease (01.09.2016)
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Journal Article
Epitranscriptomic reader YTHDF2 regulates SEK1(MAP2K4)-JNK-cJUN inflammatory signaling in astrocytes during neurotoxic stress
Malovic, Emir, Ealy, Alyssa, Miller, Cameron, Jang, Ahyoung, Hsu, Phillip J., Sarkar, Souvarish, Rokad, Dharmin, Goeser, Cody, Hartman, Aleah Kristen, Zhu, Allen, Palanisamy, Bharathi, Zenitsky, Gary, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, He, Chuan, Kanthasamy, Anumantha G.
Published in iScience (20.09.2024)
Published in iScience (20.09.2024)
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Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia
Panicker, Nikhil, Sarkar, Souvarish, Harischandra, Dilshan S, Neal, Matthew, Kam, Tae-In, Jin, Huajun, Saminathan, Hariharan, Langley, Monica, Charli, Adhithiya, Samidurai, Manikandan, Rokad, Dharmin, Ghaisas, Shivani, Pletnikova, Olga, Dawson, Valina L, Dawson, Ted M, Anantharam, Vellareddy, Kanthasamy, Anumantha G, Kanthasamy, Arthi
Published in The Journal of experimental medicine (03.06.2019)
Published in The Journal of experimental medicine (03.06.2019)
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Journal Article
Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson's disease
Sarkar, Souvarish, Nguyen, Hai M, Malovic, Emir, Luo, Jie, Langley, Monica, Palanisamy, Bharathi N, Singh, Neeraj, Manne, Sireesha, Neal, Matthew, Gabrielle, Michelle, Abdalla, Ahmed, Anantharam, Poojya, Rokad, Dharmin, Panicker, Nikhil, Singh, Vikrant, Ay, Muhammet, Charli, Adhithiya, Harischandra, Dilshan, Jin, Lee-Way, Jin, Huajun, Rangaraju, Srikant, Anantharam, Vellareddy, Wulff, Heike, Kanthasamy, Anumantha G
Published in The Journal of clinical investigation (01.08.2020)
Published in The Journal of clinical investigation (01.08.2020)
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Journal Article
Environmental neurotoxicant manganese regulates exosome-mediated extracellular miRNAs in cell culture model of Parkinson's disease: Relevance to α-synuclein misfolding in metal neurotoxicity
Harischandra, Dilshan S., Ghaisas, Shivani, Rokad, Dharmin, Zamanian, Mostafa, Jin, Huajun, Anantharam, Vellareddy, Kimber, Michael, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Published in Neurotoxicology (Park Forest South) (01.01.2018)
Published in Neurotoxicology (Park Forest South) (01.01.2018)
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Journal Article
Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson's disease
Sarkar, Souvarish, Malovic, Emir, Harishchandra, Dilshan S, Ghaisas, Shivani, Panicker, Nikhil, Charli, Adhithiya, Palanisamy, Bharathi N, Rokad, Dharmin, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G
Published in NPJ Parkinson's Disease (17.10.2017)
Published in NPJ Parkinson's Disease (17.10.2017)
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Enhanced differentiation of human dopaminergic neuronal cell model for preclinical translational research in Parkinson's disease
Harischandra, Dilshan S., Rokad, Dharmin, Ghaisas, Shivani, Verma, Saurabh, Robertson, Alan, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Published in Biochimica et biophysica acta. Molecular basis of disease (01.04.2020)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.04.2020)
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Journal Article
Role of Neurotoxicants and Traumatic Brain Injury in α-Synuclein Protein Misfolding and Aggregation
Rokad, Dharmin, Ghaisas, Shivani, Harischandra, Dilshan S, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G
Published in Brain research bulletin (01.07.2017)
Published in Brain research bulletin (01.07.2017)
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Characterization and comparative analysis of a new mouse microglial cell model for studying neuroinflammatory mechanisms during neurotoxic insults
Sarkar, Souvarish, Malovic, Emir, Sarda, Deeksha, Lawana, Vivek, Rokad, Dharmin, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Published in Neurotoxicology (Park Forest South) (01.07.2018)
Published in Neurotoxicology (Park Forest South) (01.07.2018)
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Journal Article
Exosomes as Mediators of Chemical-Induced Toxicity
Rokad, Dharmin, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Published in Current environmental health reports (01.09.2019)
Published in Current environmental health reports (01.09.2019)
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Journal Article
Environmental neurotoxicant manganese regulates exosome-mediated extracellular miRNAs in cell culture model of Parkinson's disease: Relevance to a-synuclein misfolding in metal neurotoxicity
Harischandra, Dilshan S, Ghaisas, Shivani, Rokad, Dharmin, Zamanian, Mostafa, Jin, Huajun, Anantharam, Vellareddy, Kimber, Michael, Kanthasamy, Arthi, Kanthasamy, Anumantha G
Published in Neurotoxicology (Park Forest South) (01.01.2018)
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Published in Neurotoxicology (Park Forest South) (01.01.2018)
Journal Article
Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease
Gordon, Richard, Singh, Neeraj, Lawana, Vivek, Ghosh, Anamitra, Harischandra, Dilshan S., Jin, Huajun, Hogan, Colleen, Sarkar, Souvarish, Rokad, Dharmin, Panicker, Nikhil, Anantharam, Vellareddy, Kanthasamy, Anumantha G., Kanthasamy, Arthi
Published in Neurobiology of disease (01.09.2016)
Published in Neurobiology of disease (01.09.2016)
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Journal Article
Epitranscriptomic Reader YTHDF2 Regulates SEK1( MAP2K4 )-JNK-cJUN Inflammatory Signaling in Astrocytes during Neurotoxic Stress
Malovic, Emir, Ealy, Alyssa, Hsu, Phillip J, Sarkar, Souvarish, Miller, Cameron, Rokad, Dharmin, Goeser, Cody, Hartman, Aleah Kristen, Zhu, Allen, Palanisamy, Bharathi, Zenitsky, Gary, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, He, Chuan, Kanthasamy, Anumantha G
Published in bioRxiv (26.01.2024)
Published in bioRxiv (26.01.2024)
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