The PI3K∂-Selective Inhibitor Idelalisib Induces T- and NK-Cell Dysfunction Independently of B-Cell Malignancy-Associated Immunosuppression
Rohrbacher, Lisa, Brauchle, Bettina, Ogrinc Wagner, Ana, von Bergwelt-Baildon, Michael, Bücklein, Veit L, Subklewe, Marion
Published in Frontiers in immunology (15.03.2021)
Published in Frontiers in immunology (15.03.2021)
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T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals
Philipp, Nora, Kazerani, Maryam, Nicholls, Alyssa, Vick, Binje, Wulf, Jan, Straub, Tobias, Scheurer, Michaela, Muth, Amelie, Hänel, Gerulf, Nixdorf, Daniel, Sponheimer, Monika, Ohlmeyer, Malte, Lacher, Sonja M., Brauchle, Bettina, Marcinek, Anetta, Rohrbacher, Lisa, Leutbecher, Alexandra, Rejeski, Kai, Weigert, Oliver, von Bergwelt-Baildon, Michael, Theurich, Sebastian, Kischel, Roman, Jeremias, Irmela, Bücklein, Veit, Subklewe, Marion
Published in Blood (08.09.2022)
Published in Blood (08.09.2022)
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Journal Article
Beyond Mitigating Immune-Related Adverse Events: Glucocorticoids Ameliorate Bispecific Antibody-Mediated T-Cell Exhaustion I n Vitro
Muth, Amelie, Philipp, Nora, Marcinek, Anetta, Straub, Tobias, Winter, Lis, Hänel, Gerulf, Nixdorf, Daniel, Rohrbacher, Lisa, Buecklein, Veit L., Subklewe, Marion
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
CD33-TIM3 Dual CAR T Cells: Enhancing Specificity While Maintaining Efficacy Against AML
Wang, Yingshuai, Lu, Wenjie, Rohrbacher, Lisa, Flaswinkel, Heinrich, Emhardt, Alica Joana, Magno, Giulia, Haubner, Sascha, Kobold, Sebastian, Leonhardt, Heinrich, Hopfner, Karl-Peter, Busch, Dirk H, Buecklein, Veit L., Nixdorf, Daniel, Subklewe, Marion
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Two Players, One Goal: BiTE ® Vs CART Targeting FLT3 in AML
Rohrbacher, Lisa, Nixdorf, Daniel, Stadler, Helena, Brauchle, Bettina, Märkl, Florian, Philipp, Nora, Hänel, Gerulf, Marcinek, Anetta, Kazerani, Maryam, Emhardt, Alica Joana, Magno, Giulia, Goldstein, Rebecca L., Straub, Tobias, Kobold, Sebastian, Chapman-Arvedson, Tara L., Buecklein, Veit L., Subklewe, Marion
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Adaptor Anti-P329G CAR T Cells for Modular Targeting of AML
Stock, Sophia, Strzalkowski, Thaddaeus, Gottschlich, Adrian, Rohrbacher, Lisa, Fertig, Luisa, Menkhoff, Vivien D., Surowka, Marlena, Bruenker, Peter, Darowski, Diana, Endres, Stefan, von Bergwelt-Baildon, Michael, Subklewe, Marion, Klein, Christian, Kobold, Sebastian
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia
Gottschlich, Adrian, Thomas, Moritz, Grünmeier, Ruth, Lesch, Stefanie, Rohrbacher, Lisa, Igl, Veronika, Briukhovetska, Daria, Benmebarek, Mohamed-Reda, Vick, Binje, Dede, Sertac, Müller, Katharina, Xu, Tao, Dhoqina, Dario, Märkl, Florian, Robinson, Sophie, Sendelhofert, Andrea, Schulz, Heiko, Umut, Öykü, Kavaka, Vladyslav, Tsiverioti, Christina Angeliki, Carlini, Emanuele, Nandi, Sayantan, Strzalkowski, Thaddäus, Lorenzini, Theo, Stock, Sophia, Müller, Philipp Jie, Dörr, Janina, Seifert, Matthias, Cadilha, Bruno L, Brabenec, Ruben, Röder, Natalie, Rataj, Felicitas, Nüesch, Manuel, Modemann, Franziska, Wellbrock, Jasmin, Fiedler, Walter, Kellner, Christian, Beltrán, Eduardo, Herold, Tobias, Paquet, Dominik, Jeremias, Irmela, von Baumgarten, Louisa, Endres, Stefan, Subklewe, Marion, Marr, Carsten, Kobold, Sebastian
Published in Nature biotechnology (01.11.2023)
Published in Nature biotechnology (01.11.2023)
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A modular and controllable T cell therapy platform for acute myeloid leukemia
Benmebarek, Mohamed-Reda, Cadilha, Bruno L, Herrmann, Monika, Lesch, Stefanie, Schmitt, Saskia, Stoiber, Stefan, Darwich, Abbass, Augsberger, Christian, Brauchle, Bettina, Rohrbacher, Lisa, Oner, Arman, Seifert, Matthias, Schwerdtfeger, Melanie, Gottschlich, Adrian, Rataj, Felicitas, Fenn, Nadja C, Klein, Christian, Subklewe, Marion, Endres, Stefan, Hopfner, Karl-Peter, Kobold, Sebastian
Published in Leukemia (01.08.2021)
Published in Leukemia (01.08.2021)
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Journal Article
The Race Is on: BiTE Vs CART As FLT3-Directed Immunotherapies in AML
Rohrbacher, Lisa, Nixdorf, Daniel, Stadler, Helena, Brauchle, Bettina, Märkl, Florian, Phillip, Nora, Hänel, Gerulf, Marcinek, Anetta, Kazerani, Maryam, Goldstein, Rebecca, von Bergwelt, Michael, Kobold, Sebastian, Buecklein, Veit L, Chapman-Arvedson, Tara, Subklewe, Marion
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Uncovering the Enemy: Single-Cell Transcriptional Profiling of Measurable Residual Disease (MRD) Cells
Kazerani, Maryam, Wange, Lucas, Tast, Benjamin, Solovey, Maria, Nixdorf, Daniel, Rohrbacher, Lisa, Heitmüller, Christina, Koehnke, Thomas, Schnorfeil, Frauke, Grunwald, Victoria V, Spiekermann, Karsten, Metzeler, Klaus H., Hopfner, Karl-Peter, Enard, Wolfgang, Buecklein, Veit L, Subklewe, Marion
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Evolution of T-cell fitness through AML progression: enhanced bispecific T-cell engager-mediated function of bone marrow T cells at remission compared to initial diagnosis and relapse
Kazerani, Maryam, Marcinek, Anetta, Philipp, Nora, Brauchle, Bettina, Taylor, Jonathan Jonas, Moreno, Helena Domínguez, Terrasi, Andrea, Tast, Benjamin, Rohrbacher, Lisa, Wang, Yingshuai, Warm, Maximilian, Emhardt, Alica-Joana, Magno, Giulia, Spiekermann, Karsten, Herold, Tobias, Straub, Tobias, Theurich, Sebastian, Schotta, Gunnar, Kischel, Roman, Bücklein, Veit L, Subklewe, Marion
Published in Leukemia (22.08.2024)
Published in Leukemia (22.08.2024)
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Journal Article
Targeting FLT3 with a new-generation antibody-drug conjugate in combination with kinase inhibitors for treatment of AML
Roas, Maike, Vick, Binje, Kasper, Marc-André, Able, Marina, Polzer, Harald, Gerlach, Marcus, Kremmer, Elisabeth, Hecker, Judith S., Schmitt, Saskia, Stengl, Andreas, Waller, Verena, Hohmann, Natascha, Festini, Moreno, Ludwig, Alexander, Rohrbacher, Lisa, Herold, Tobias, Subklewe, Marion, Götze, Katharina S., Hackenberger, Christian P. R., Schumacher, Dominik, Helma-Smets, Jonas, Jeremias, Irmela, Leonhardt, Heinrich, Spiekermann, Karsten
Published in Blood (02.03.2023)
Published in Blood (02.03.2023)
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Journal Article
CD33 BiTE® molecule-mediated immune synapse formation and subsequent T-cell activation is determined by the expression profile of activating and inhibitory checkpoint molecules on AML cells
Marcinek, Anetta, Brauchle, Bettina, Rohrbacher, Lisa, Hänel, Gerulf, Philipp, Nora, Märkl, Florian, Strzalkowski, Thaddäus, Lacher, Sonja M., Udiljak, Dragica, Spiekermann, Karsten, Theurich, Sebastian, Kobold, Sebastian, Kischel, Roman, James, John R., Bücklein, Veit L., Subklewe, Marion
Published in Cancer Immunology, Immunotherapy (01.07.2023)
Published in Cancer Immunology, Immunotherapy (01.07.2023)
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Journal Article
Treatment-Free Intervals Mitigate T-Cell Exhaustion Induced By Continuous CD19xCD3-BiTE® Construct Stimulation in Vitro
Zieger, Nora, Nicholls, Alyssa, Wulf, Jan, Hänel, Gerulf, Kazerani Pasikhani, Maryam, Buecklein, Veit, Brauchle, Bettina, Marcinek, Anetta, Nixdorf, Daniel, Rohrbacher, Lisa, Scheurer, Michaela, Kischel, Roman, Spiekermann, Karsten, Weigert, Oliver, Theurich, Sebastian, von Bergwelt, Michael, Subklewe, Marion
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Correction to: CD33 BiTE® molecule-mediated immune synapse formation and subsequent T-cell activation is determined by the expression profile of activating and inhibitory checkpoint molecules on AML cells
Marcinek, Anetta, Brauchle, Bettina, Rohrbacher, Lisa, Hänel, Gerulf, Philipp, Nora, Märkl, Florian, Strzalkowski, Thaddäus, Lacher, Sonja M., Udiljak, Dragica, Spiekermann, Karsten, Theurich, Sebastian, Kobold, Sebastian, Kischel, Roman, James, John R., Bücklein, Veit L., Subklewe, Marion
Published in Cancer Immunology, Immunotherapy (01.07.2023)
Published in Cancer Immunology, Immunotherapy (01.07.2023)
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Journal Article
Treatment-Free Intervals during CD19xCD3 BiTE ® Construct-Mediated T-Cell Stimulation Induce Functional Reinvigoration and Transcriptional Reprogramming of Exhausted T Cells
Zieger, Nora, Kazerani Pasikhani, Maryam, Straub, Tobias, Nicholls, Alyssa, Hänel, Gerulf, Wulf, Jan, Scheurer, Michaela, Nixdorf, Daniel, Sponheimer, Monika, Lacher, Sonja M, Brauchle, Bettina, Marcinek, Anetta, Rohrbacher, Lisa, Leutbecher, Alexandra, von Bergwelt, Michael, Spiekermann, Karsten, Weigert, Oliver, Theurich, Sebastian, Buecklein, Veit L, Kischel, Roman, Subklewe, Marion
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Abstract 894: The race is on: BiTE vs CART targeting FLT3 in AML
Rohrbacher, Lisa, Nixdorf, Daniel, Stadler, Helena, Brauchle, Bettina, Märkl, Florian, Philipp, Nora, Hänel, Gerulf, Marcinek, Anetta, Kazerani, Maryam, Goldstein, Rebecca L., von Bergwelt, Michael, Kobold, Sebastian, Bücklein, Veit L., Arvedson, Tara, Subklewe, Marion
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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