Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics
Zenke, Simon, Palm, Margriet M., Braun, Julia, Gavrilov, Alina, Meiser, Philippa, Böttcher, Jan P., Beyersdorf, Niklas, Ehl, Stephan, Gerard, Audrey, Lämmermann, Tim, Schumacher, Ton N., Beltman, Joost B., Rohr, Jan C.
Published in Immunity (Cambridge, Mass.) (18.02.2020)
Published in Immunity (Cambridge, Mass.) (18.02.2020)
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Differential trafficking of ligands trogocytosed via CD28 versus CTLA4 promotes collective cellular control of co-stimulation
Zenke, Simon, Sica, Mauricio P., Steinberg, Florian, Braun, Julia, Zink, Alicia, Gavrilov, Alina, Hilger, Alexander, Arra, Aditya, Brunner-Weinzierl, Monika, Elling, Roland, Beyersdorf, Niklas, Lämmermann, Tim, Smulski, Cristian R., Rohr, Jan C.
Published in Nature communications (29.10.2022)
Published in Nature communications (29.10.2022)
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Heterogeneous Differentiation Patterns of Individual CD8⁺ T Cells
Gerlach, Carmen, Rohr, Jan C., Perié, Leïla, van Rooij, Nienke, van Heijst, Jeroen W. J., Velds, Arno, Urbanus, Jos, Naik, Shalin H., Jacobs, Heinz, Beltman, Joost B., de Boer, Rob J., Schumacher, Ton N. M.
Published in Science (American Association for the Advancement of Science) (03.05.2013)
Published in Science (American Association for the Advancement of Science) (03.05.2013)
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Familial Hemophagocytic Lymphohistiocytosis Type 5 (FHL-5) Is Caused by Mutations in Munc18-2 and Impaired Binding to Syntaxin 11
zur Stadt, Udo, Rohr, Jan, Seifert, Wenke, Koch, Florian, Grieve, Samantha, Pagel, Julia, Strauß, Julia, Kasper, Brigitte, Nürnberg, Gudrun, Becker, Christian, Maul-Pavicic, Andrea, Beutel, Karin, Janka, Gritta, Griffiths, Gillian, Ehl, Stephan, Hennies, Hans Christian
Published in American journal of human genetics (09.10.2009)
Published in American journal of human genetics (09.10.2009)
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Comprehensive infectious disease screening in a cohort of unaccompanied refugee minors in Germany from 2016 to 2017: A cross-sectional study
Janda, Ales, Eder, Kristin, Fressle, Roland, Geweniger, Anne, Diffloth, Natalie, Heeg, Maximilian, Binder, Nadine, Sitaru, Ana-Gabriela, Rohr, Jan, Henneke, Philipp, Hufnagel, Markus, Elling, Roland
Published in PLoS medicine (01.03.2020)
Published in PLoS medicine (01.03.2020)
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Functional Relevance of CTLA4 Variants: an Upgraded Approach to Assess CTLA4-Dependent Transendocytosis by Flow Cytometry
Rojas-Restrepo, Jessica, Sindram, Elena, Zenke, Simon, Haberstroh, Hanna, Mitsuiki, Noriko, Gabrysch, Annemarie, Huebscher, Katrin, Posadas-Cantera, Sara, Krausz, Máté, Kobbe, Robin, Rohr, Jan C., Grimbacher, Bodo, Gámez-Díaz, Laura
Published in Journal of clinical immunology (01.11.2023)
Published in Journal of clinical immunology (01.11.2023)
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Journal Article
Single cell behavior in T cell differentiation
Rohr, Jan C, Gerlach, Carmen, Kok, Lianne, Schumacher, Ton N
Published in Trends in immunology (01.04.2014)
Published in Trends in immunology (01.04.2014)
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Hyperactive mTOR pathway promotes lymphoproliferation and abnormal differentiation in autoimmune lymphoproliferative syndrome
Völkl, Simon, Rensing-Ehl, Anne, Allgäuer, Andrea, Schreiner, Elisabeth, Lorenz, Myriam Ricarda, Rohr, Jan, Klemann, Christian, Fuchs, Ilka, Schuster, Volker, von Bueren, André O., Naumann-Bartsch, Nora, Gambineri, Eleonora, Siepermann, Kathrin, Kobbe, Robin, Nathrath, Michaela, Arkwright, Peter D., Miano, Maurizio, Stachel, Klaus-Daniel, Metzler, Markus, Schwarz, Klaus, Kremer, Anita N., Speckmann, Carsten, Ehl, Stephan, Mackensen, Andreas
Published in Blood (14.07.2016)
Published in Blood (14.07.2016)
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Correction to: Functional Relevance of CTLA4 Variants: an Upgraded Approach to Assess CTLA4‑Dependent Transendocytosis by Flow Cytometry
Rojas‑Restrepo, Jessica, Sindram, Elena, Zenke, Simon, Haberstroh, Hanna, Mitsuiki, Noriko, Gabrysch, Annemarie, Huebscher, Katrin, Posadas‑Cantera, Sara, Krausz, Máté, Kobbe, Robin, Rohr, Jan C., Grimbacher, Bodo, Gamez‑Diaz, Laura
Published in Journal of clinical immunology (01.11.2023)
Published in Journal of clinical immunology (01.11.2023)
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Transplantation from a symptomatic carrier sister restores host defenses but does not prevent colitis in NEMO deficiency
Klemann, Christian, Pannicke, Ulrich, Morris-Rosendahl, Deborah J, Vlantis, Katerina, Rizzi, Marta, Uhlig, Holm, Vraetz, Thomas, Speckmann, Carsten, Strahm, Brigitte, Pasparakis, Manolis, Schwarz, Klaus, Ehl, Stephan, Rohr, Jan C
Published in Clinical immunology (Orlando, Fla.) (01.03.2016)
Published in Clinical immunology (Orlando, Fla.) (01.03.2016)
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Evolution of disease activity and biomarkers on and off rapamycin in 28 patients with autoimmune lymphoproliferative syndrome
Klemann, Christian, Esquivel, Myrian, Magerus-Chatinet, Aude, Lorenz, Myriam R, Fuchs, Ilka, Neveux, Nathalie, Castelle, Martin, Rohr, Jan, da Cunha, Claudia Bettoni, Ebinger, Martin, Kobbe, Robin, Kremens, Bernhard, Kollert, Florian, Gambineri, Eleonora, Lehmberg, Kai, Seidel, Markus G, Siepermann, Kathrin, Voelker, Thomas, Schuster, Volker, Goldacker, Sigune, Schwarz, Klaus, Speckmann, Carsten, Picard, Capucine, Fischer, Alain, Rieux-Laucat, Frederic, Ehl, Stephan, Rensing-Ehl, Anne, Neven, Benedicte
Published in Haematologica (Roma) (01.02.2017)
Published in Haematologica (Roma) (01.02.2017)
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Analyzing trogocytosis of T lymphocytes by flow cytometry and confocal microscopy
Zink, Alicia, Zenke, Simon, Wiese, Teresa, Beyersdorf, Niklas, Lämmermann, Tim, Rohr, Jan C.
Published in STAR protocols (17.03.2023)
Published in STAR protocols (17.03.2023)
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Assessing T lymphocyte function and differentiation by genetically encoded reporter systems
Hoekstra, Mirjam E, Dijkgraaf, Feline E, Schumacher, Ton N, Rohr, Jan C
Published in Trends in immunology (01.07.2015)
Published in Trends in immunology (01.07.2015)
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Reproducibility of Illumina platform deep sequencing errors allows accurate determination of DNA barcodes in cells
Beltman, Joost B, Urbanus, Jos, Velds, Arno, van Rooij, Nienke, Rohr, Jan C, Naik, Shalin H, Schumacher, Ton N
Published in BMC bioinformatics (02.04.2016)
Published in BMC bioinformatics (02.04.2016)
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Hemophagocytic lymphohistiocytosis as presenting manifestation of profound combined immunodeficiency due to an ORAI1 mutation
Klemann, Christian, MD, Ammann, Sandra, PhD, Heizmann, Miriam, Fuchs, Sebastian, PhD, Bode, Sebastian F., MD, Heeg, Maximilian, MD, Fuchs, Hans, MD, Lehmberg, Kai, MD, zur Stadt, Udo, MD, Roll, Claudia, MD, Vraetz, Thomas, MD, Speckmann, Carsten, MD, Lorenz, Myriam Ricarda, PhD, Schwarz, Klaus, MD, Rohr, Jan, MD, Feske, Stefan, MD, Ehl, Stephan, MD
Published in Journal of allergy and clinical immunology (01.12.2017)
Published in Journal of allergy and clinical immunology (01.12.2017)
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Increased proportions of γδ T lymphocytes in atypical SCID associate with disease manifestations
Tometten, Inga, Felgentreff, Kerstin, Hönig, Manfred, Hauck, Fabian, Albert, Michael H., Niehues, Tim, Perez, Ruy, Ghosh, Sujal, Picard, Capucine, Stary, Jan, Formankova, Renata, Worth, Austen, Soler-Palacín, Pere, García-Prat, Marina, Allende, Luis M., Gonzalez-Granado, Luis Ignacio, Stepensky, Polina, Di Cesare, Silvia, Scarselli, Alessia, Cancrini, Caterina, Speckmann, Carsten, Gilmour, Kimberly, Notarangelo, Luigi, Ehl, Stephan, Rohr, Jan C.
Published in Clinical immunology (Orlando, Fla.) (01.04.2019)
Published in Clinical immunology (Orlando, Fla.) (01.04.2019)
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Lethal hemophagocytic lymphohistiocytosis in Hermansky-Pudlak syndrome type II
Enders, Anselm, Zieger, Barbara, Schwarz, Klaus, Yoshimi, Ayami, Speckmann, Carsten, Knoepfle, Eva-Maria, Kontny, Udo, Müller, Christoph, Nurden, Alan, Rohr, Jan, Henschen, Matthias, Pannicke, Ulrich, Niemeyer, Charlotte, Nurden, Paquita, Ehl, Stephan
Published in Blood (01.07.2006)
Published in Blood (01.07.2006)
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Targeted Gene Panel Sequencing for Early-onset Inflammatory Bowel Disease and Chronic Diarrhea
Petersen, Britt-Sabina, August, Dietrich, Abt, Renate, Alddafari, Moudjahed, Atarod, Lida, Baris, Safa, Bhavsar, Hemant, Brinkert, Florian, Buchta, Mary, Bulashevska, Alla, Chee, Ronnie, Cordeiro, Ana I, Dara, Naghi, Dückers, Gregor, Elmarsafy, Aisha, Frede, Natalie, Galal, Nermeen, Gerner, Patrick, Glocker, Erik-Oliver, Goldacker, Sigune, Hammermann, Jutta, Hasselblatt, Peter, Havlicekova, Zuzana, Hübscher, Katrin, Jesenak, Milos, Karaca, Neslihan E, Karakoc-Aydiner, Elif, Kharaghani, Mahboubeh M, Kilic, Sara S, Kiykim, Ayca, Klein, Christoph, Klemann, Christian, Kobbe, Robin, Kotlarz, Daniel, Laass, Martin W, Leahy, T Ronan, Mesdaghi, Mehrnaz, Mitton, Sally, Neves, João F, Öztürk, Birol, Pereira, Luis F, Rohr, Jan, Restrepo, Jessica L R, Ruzaike, Gunda, Saleh, Nadia, Seneviratne, Suranjith, Senol, Ebru, Speckmann, Carsten, Tegtmeyer, Daniel, Thankam, Paul, van der Werff Ten Bosch, Jutte, von Bernuth, Horst, Zeissig, Sebastian, Zeissig, Yvonne, Franke, Andre, Grimbacher, Bodo
Published in Inflammatory bowel diseases (01.12.2017)
Published in Inflammatory bowel diseases (01.12.2017)
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Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases
ROHR, Jan, BEUTEL, Karin, WOESSMANN, Wilhelm, GROLL, Andreas H, STRAHM, Brigitte, PAGEL, Julia, SPECKMANN, Carsten, JANKA, Gritta, GRIFFITHS, Gillian, SCHWARZ, Klaus, ZUR STADT, Udo, EHL, Stephan, MAUL-PAVICIC, Andrea, VRAETZ, Thomas, THIEL, Jens, WARNATZ, Klaus, BONDZIO, Ilka, GROSS-WIELTSCH, Ute, SCHÜNDELN, Michael, SCHÜTZ, Barbara
Published in Haematologica (Roma) (01.12.2010)
Published in Haematologica (Roma) (01.12.2010)
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Proinflammatory cytokine response toward fungi but not bacteria in chronic granulomatous disease
Gazendam, Roel P., MD, van de Geer, Annemarie, MD, van Hamme, John L., BSc, Helgers, Leanne, BSc, Rohr, Jan, MD, PhD, Chrabieh, Maya, MD, PhD, Picard, Capucine, MD, PhD, Roos, Dirk, PhD, van den Berg, J. Merlijn, MD, PhD, van den Berg, T.K., PhD, Kuijpers, Taco W., MD, PhD
Published in Journal of allergy and clinical immunology (01.09.2016)
Published in Journal of allergy and clinical immunology (01.09.2016)
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