IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
Turcan, Sevin, Rohle, Daniel, Goenka, Anuj, Walsh, Logan A., Fang, Fang, Yilmaz, Emrullah, Campos, Carl, Fabius, Armida W. M., Lu, Chao, Ward, Patrick S., Thompson, Craig B., Kaufman, Andrew, Guryanova, Olga, Levine, Ross, Heguy, Adriana, Viale, Agnes, Morris, Luc G. T., Huse, Jason T., Mellinghoff, Ingo K., Chan, Timothy A.
Published in Nature (London) (15.02.2012)
Published in Nature (London) (15.02.2012)
Get full text
Journal Article
Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo
Venneti, Sriram, Dunphy, Mark P, Zhang, Hanwen, Pitter, Kenneth L, Zanzonico, Patrick, Campos, Carl, Carlin, Sean D, La Rocca, Gaspare, Lyashchenko, Serge, Ploessl, Karl, Rohle, Daniel, Omuro, Antonio M, Cross, Justin R, Brennan, Cameron W, Weber, Wolfgang A, Holland, Eric C, Mellinghoff, Ingo K, Kung, Hank F, Lewis, Jason S, Thompson, Craig B
Published in Science translational medicine (11.02.2015)
Published in Science translational medicine (11.02.2015)
Get more information
Journal Article
Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors
Vivanco, Igor, Robins, H Ian, Rohle, Daniel, Campos, Carl, Grommes, Christian, Nghiemphu, Phioanh Leia, Kubek, Sara, Oldrini, Barbara, Chheda, Milan G, Yannuzzi, Nicolas, Tao, Hui, Zhu, Shaojun, Iwanami, Akio, Kuga, Daisuke, Dang, Julie, Pedraza, Alicia, Brennan, Cameron W, Heguy, Adriana, Liau, Linda M, Lieberman, Frank, Yung, W K Alfred, Gilbert, Mark R, Reardon, David A, Drappatz, Jan, Wen, Patrick Y, Lamborn, Kathleen R, Chang, Susan M, Prados, Michael D, Fine, Howard A, Horvath, Steve, Wu, Nian, Lassman, Andrew B, DeAngelis, Lisa M, Yong, William H, Kuhn, John G, Mischel, Paul S, Mehta, Minesh P, Cloughesy, Timothy F, Mellinghoff, Ingo K
Published in Cancer discovery (01.05.2012)
Published in Cancer discovery (01.05.2012)
Get full text
Journal Article
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer
Oldrini, Barbara, Hsieh, Wan-Ying, Erdjument-Bromage, Hediye, Codega, Paolo, Carro, Maria Stella, Curiel-García, Alvaro, Campos, Carl, Pourmaleki, Maryam, Grommes, Christian, Vivanco, Igor, Rohle, Daniel, Bielski, Craig M., Taylor, Barry S., Hollmann, Travis J., Rosenblum, Marc, Tempst, Paul, Blenis, John, Squatrito, Massimo, Mellinghoff, Ingo K.
Published in Nature communications (11.12.2017)
Published in Nature communications (11.12.2017)
Get full text
Journal Article
phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation
Vivanco, Igor, Rohle, Daniel, Versele, Matthias, Iwanami, Akio, Kuga, Daisuke, Oldrini, Barbara, Tanaka, Kazuhiro, Dang, Julie, Kubek, Sara, Palaskas, Nicolaos, Hsueh, Teli, Evans, Michael, Mulholland, David, Wolle, Daniel, Rajasekaran, Sigrid, Rajasekaran, Ayyappan, Liau, Linda M, Cloughesy, Timothy F, Dikic, Ivan, Brennan, Cameron, Wu, Hong, Mischel, Paul S, Perera, Timothy, Mellinghoff, Ingo K
Published in Proceedings of the National Academy of Sciences - PNAS (06.04.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (06.04.2010)
Get full text
Journal Article
Abstract 1703: Sensitizing cancer cells to TNF induced cell death by the BET-inhibitor RG6146
Wellinger, Lisa C., Hogg, Simon J., Newman, Dane, Friess, Thomas, Geiss, Daniela, Bacac, Marina, Fauti, Tanja, Ruefli-Brasse, Astrid, Johnstone, Ricky W., Rohle, Daniel
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Get full text
Journal Article
DUSP4 protects BRAF- and NRAS-mutant melanoma from oncogene overdose through modulation of MITF
Gutierrez-Prat, Nuria, Zuberer, Hedwig L, Mangano, Luca, Karimaddini, Zahra, Wolf, Luise, Tyanova, Stefka, Wellinger, Lisa C, Marbach, Daniel, Griesser, Vera, Pettazzoni, Piergiorgio, Bischoff, James R, Rohle, Daniel, Palladino, Chiara, Vivanco, Igor
Published in Life science alliance (01.09.2022)
Published in Life science alliance (01.09.2022)
Get full text
Journal Article
BET Inhibition Enhances TNF-Mediated Antitumor Immunity
Wellinger, Lisa C, Hogg, Simon J, Newman, Dane M, Friess, Thomas, Geiss, Daniela, Michie, Jessica, Ramsbottom, Kelly M, Bacac, Marina, Fauti, Tanja, Marbach, Daniel, Jarassier, Laura, Thienger, Phillip, Paehler, Axel, Cluse, Leonie A, Kearney, Conor J, Vervoort, Stephin J, Trapani, Joseph A, Oliaro, Jane, Shortt, Jake, Ruefli-Brasse, Astrid, Rohle, Daniel, Johnstone, Ricky W
Published in Cancer immunology research (01.01.2022)
Published in Cancer immunology research (01.01.2022)
Get more information
Journal Article
TM-15GLUTAMINE BASED PET IMAGING FACILITATES ENHANCED METABOLIC DETECTION OF GLIOMAS IN VIVO
Venneti, Sriram, Dunphy, Mark, Zhang, Hanwen, Pitter, Kenneth, Campos, Carl, Carlin, Sean, Lyashchenko, Serge, Plöessl, Carl, Rohle, Daniel, Omuro, Antonio, Cross, Justin, Brennan, Cameron, Weber, Wolfgang, Holland, Eric, Mellinghoff, Ingo, Kung, Hank, Lewis, Jason, Thompson, Craig
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
Get full text
Journal Article
TM-15 GLUTAMINE BASED PET IMAGING FACILITATES ENHANCED METABOLIC DETECTION OF GLIOMAS IN VIVO
Venneti, S., Dunphy, M., Zhang, H., Pitter, K., Campos, C., Carlin, S., Lyashchenko, S., Ploessl, C., Rohle, D., Omuro, A., Cross, J., Brennan, C., Weber, W., Holland, E., Mellinghoff, I., Kung, H., Lewis, J., Thompson, C.
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.11.2014)
Get full text
Journal Article
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
Turcan, Sevin, Rohle, Daniel, Goenka, Anuj, Walsh, Logan A, Fang, Fang, Yilmaz, Emrullah, Campos, Carl, Fabius, Armida W.M, Lu, Chao, Ward, Patrick S, Thompson, Craig B, Kaufman, Andrew, Guryanova, Olga, Levine, Ross, Heguy, Adriana, Viale, Agnes, Morris, Luc G.T, Huse, Jason T, Mellinghoff, Ingo K, Chan, Timothy A
Published in Nature (London) (22.03.2012)
Published in Nature (London) (22.03.2012)
Get full text
Journal Article
BET Inhibition Enhances TNF Mediated Anti-Tumor Immunity
Wellinger, Lisa C, Hogg, Simon J, Newman, Dane M, Friess, Thomas, Geiss, Daniela, Michie, Jessica, Ramsbottom, Kelly M, Bacac, Marina, Fauti, Tanja, Marbach, Daniel, Jarassier, Laura, Thienger, Phillip, Paehler, Axel, Cluse, Leonie A, Kearney, Conor J, Vervoort, Stephin J, Oliaro, Jane, Shortt, Jake, Ruefli-Brasse, Astrid, Rohle, Daniel, Johnstone, Ricky W
Published in bioRxiv (15.02.2021)
Published in bioRxiv (15.02.2021)
Get full text
Paper