Design of Poly(lactic- co -glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis
Yang, Haitao, Li, Jing, Patel, Sravan Kumar, Palmer, Kenneth E, Devlin, Brid, Rohan, Lisa C
Published in Pharmaceutics (16.04.2019)
Published in Pharmaceutics (16.04.2019)
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Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA)
Li Salie, Zhe, Kirby, Karen A., Michailidis, Eleftherios, Marchand, Bruno, Singh, Kamalendra, Rohan, Lisa C., Kodama, Eiichi N., Mitsuya, Hiroaki, Parniak, Michael A., Sarafianos, Stefan G.
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2016)
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A topical rectal douche product containing Q-Griffithsin does not disrupt the epithelial border or alter CD4 + cell distribution in the human rectal mucosa
Franzén Boger, Mathias, Benhach, Nora, Hasselrot, Tyra, Brand, Rhonda M, Rohan, Lisa C, Wang, Lin, McGowan, Ian, Edick, Stacey, Ho, Ken, Meyn, Leslie, Matoba, Nobuyuki, Palmer, Kenneth E, Broliden, Kristina, Tjernlund, Annelie
Published in Scientific reports (09.05.2023)
Published in Scientific reports (09.05.2023)
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In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide
Rohan, Lisa C, Moncla, Bernard J, Kunjara Na Ayudhya, Ratiya Pamela, Cost, Marilyn, Huang, Yunda, Gai, Fang, Billitto, Nicole, Lynam, J D, Pryke, Kara, Graebing, Phillip, Hopkins, Nicole, Rooney, James F, Friend, David, Dezzutti, Charlene S
Published in PloS one (19.02.2010)
Published in PloS one (19.02.2010)
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Is wetter better? An evaluation of over-the-counter personal lubricants for safety and anti-HIV-1 activity
Dezzutti, Charlene S, Brown, Elizabeth R, Moncla, Bernard, Russo, Julie, Cost, Marilyn, Wang, Lin, Uranker, Kevin, Kunjara Na Ayudhya, Ratiya P, Pryke, Kara, Pickett, Jim, Leblanc, Marc-André, Rohan, Lisa C
Published in PloS one (07.11.2012)
Published in PloS one (07.11.2012)
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Label-free analysis of tenofovir delivery to vaginal tissue using co-registered confocal Raman spectroscopy and optical coherence tomography
Chuchuen, Oranat, Maher, Jason R, Henderson, Marcus H, Desoto, Michael, Rohan, Lisa C, Wax, Adam, Katz, David F
Published in PloS one (29.09.2017)
Published in PloS one (29.09.2017)
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A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study)
Mcgowan, Ian, Cranston, Ross D, Duffill, Kathryn, Siegel, Aaron, Engstrom, Jarret C, Nikiforov, Alexyi, Jacobson, Cindy, Rehman, Khaja K, Elliott, Julie, Khanukhova, Elena, Abebe, Kaleab, Mauck, Christine, Spiegel, Hans M L, Dezzutti, Charlene S, Rohan, Lisa C, Marzinke, Mark A, Hiruy, Hiwot, Hendrix, Craig W, Richardson-Harman, Nicola, Anton, Peter A
Published in PloS one (05.05.2015)
Published in PloS one (05.05.2015)
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The effects of reproductive hormones on the physical properties of cervicovaginal fluid
Chappell, Catherine A., MD, Rohan, Lisa C., PhD, Moncla, Bernard J., PhD, Wang, Lin, MS, Meyn, Leslie A., MS, Bunge, Katherine, MD, MPH, Hillier, Sharon L., PhD
Published in American journal of obstetrics and gynecology (01.09.2014)
Published in American journal of obstetrics and gynecology (01.09.2014)
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Development and Evaluation of Nanoparticles-in-Film Technology to Achieve Extended In Vivo Exposure of MK-2048 for HIV Prevention
Tong, Xin, Patel, Sravan Kumar, Li, Jing, Patton, Dorothy, Xu, Elaine, Anderson, Peter L, Parikh, Urvi, Sweeney, Yvonne, Strizki, Julie, Hillier, Sharon L, Rohan, Lisa C
Published in Polymers (16.03.2022)
Published in Polymers (16.03.2022)
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Transport and Permeation Properties of Dapivirine: Understanding Potential Drug-Drug Interactions
Zheng, Ruohui, Valicherla, Guru R, Zhang, Junmei, Nuttall, Jeremy, Silvera, Peter, Marshall, Leslie J, Empey, Philip E, Rohan, Lisa C
Published in Pharmaceutics (01.09.2022)
Published in Pharmaceutics (01.09.2022)
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Cryopreservation of human mucosal tissues
Hughes, Sean M, Ferre, April L, Yandura, Sarah E, Shetler, Cory, Baker, Chris A R, Calienes, Fernanda, Levy, Claire N, Astronomo, Rena D, Shu, Zhiquan, Lentz, Gretchen M, Fialkow, Michael, Kirby, Anna C, McElrath, M Juliana, Sinclair, Elizabeth, Rohan, Lisa C, Anderson, Peter L, Shacklett, Barbara L, Dezzutti, Charlene S, Gao, Dayong, Hladik, Florian
Published in PloS one (30.07.2018)
Published in PloS one (30.07.2018)
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Tenofovir vaginal film as a potential MPT product against HIV-1 and HSV-2 acquisition: formulation development and preclinical assessment in non-human primates
Patel, Sravan Kumar, Agashe, Hrushikesh, Patton, Dorothy L., Sweeney, Yvonne, Beamer, May A., Hendrix, Craig W., Hillier, Sharon L., Rohan, Lisa C.
Published in Frontiers in reproductive health (10.08.2023)
Published in Frontiers in reproductive health (10.08.2023)
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In vitro transport characteristics of EFdA, a novel nucleoside reverse transcriptase inhibitor using Caco-2 and MDCKII cell monolayers
Zhang, Wei, Parniak, Michael A., Sarafianos, Stefan G., Empey, Philip E., Rohan, Lisa C.
Published in European journal of pharmacology (05.06.2014)
Published in European journal of pharmacology (05.06.2014)
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Vaginal Microbicide Gel for Delivery of IQP-0528, a Pyrimidinedione Analog with a Dual Mechanism of Action against HIV-1
MAHALINGAM, Alamelu, SIMMONS, Adam P, UGAONKAR, Shweta R, WATSON, Karen M, DEZZUTTI, Charlene S, ROHAN, Lisa C, BUCKHEIT, Robert W, KISER, Patrick F
Published in Antimicrobial Agents and Chemotherapy (01.04.2011)
Published in Antimicrobial Agents and Chemotherapy (01.04.2011)
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Development, Characterization and In Vivo Pharmacokinetic Assessment of Rectal Suppositories Containing Combination Antiretroviral Drugs for HIV Prevention
Jhunjhunwala, Kunal, Dobard, Charles W., Sharma, Sunita, Makarova, Natalia, Holder, Angela, Dinh, Chuong, Mitchell, James, Wang, Lin, Zhang, Junmei, Patel, Sravan Kumar, Heneine, Walid, Rohan, Lisa C.
Published in Pharmaceutics (21.07.2021)
Published in Pharmaceutics (21.07.2021)
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Hypo-osmolar rectal douche tenofovir formulation prevents simian/human immunodeficiency virus acquisition in macaques
Xiao, Peng, Gumber, Sanjeev, Marzinke, Mark A, Hoang, Thuy, Myers, Rohan, Date, Abhijit A, Hanes, Justin, Ensign, Laura M, Wang, Lin, Rohan, Lisa C, Cone, Richard, Fuchs, Edward J, Hendrix, Craig W, Villinger, Francois
Published in JCI insight (08.12.2022)
Published in JCI insight (08.12.2022)
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Evaluation of Combinations of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine with Clinically Used Antiretroviral Drugs
HACHIYA, Atsuko, REEVE, Aaron B, MITSUYA, Hiroaki, PARNIAK, Michael A, SARAFIANOS, Stefan G, MARCHAND, Bruno, MICHAILIDIS, Eleftherios, YEE TSUEY ONG, KIRBY, Karen A, LESLIE, Maxwell D, OKA, Shinichi, KODAMA, Eiichi N, ROHAN, Lisa C
Published in Antimicrobial Agents and Chemotherapy (01.09.2013)
Published in Antimicrobial Agents and Chemotherapy (01.09.2013)
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The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques
Cole, Alexander M, Patton, Dorothy L, Rohan, Lisa C, Cole, Amy L, Cosgrove-Sweeney, Yvonne, Rogers, Nicole A, Ratner, Deena, Sassi, Alexandra B, Lackman-Smith, Carol, Tarwater, Patrick, Ramratnam, Bharat, Ruchala, Piotr, Lehrer, Robert I, Waring, Alan J, Gupta, Phalguni
Published in PloS one (29.11.2010)
Published in PloS one (29.11.2010)
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Preformulation studies of EFdA, a novel nucleoside reverse transcriptase inhibitor for HIV prevention
Zhang, Wei, Parniak, Michael A, Mitsuya, Hiroaki, Sarafianos, Stefan G, Graebing, Phillip W, Rohan, Lisa C
Published in Drug development and industrial pharmacy (01.08.2014)
Published in Drug development and industrial pharmacy (01.08.2014)
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