Large Neutral Amino Acid Supplementation Exerts Its Effect through Three Synergistic Mechanisms: Proof of Principle in Phenylketonuria Mice
van Vliet, Danique, Bruinenberg, Vibeke M, Mazzola, Priscila N, van Faassen, Martijn H J R, de Blaauw, Pim, Kema, Ido P, Heiner-Fokkema, M Rebecca, van Anholt, Rogier D, van der Zee, Eddy A, van Spronsen, Francjan J
Published in PloS one (01.12.2015)
Published in PloS one (01.12.2015)
Get full text
Journal Article
Beyond chance? The persistence of performance in online poker
Potter van Loon, Rogier J D, van den Assem, Martijn J, van Dolder, Dennie
Published in PloS one (02.03.2015)
Published in PloS one (02.03.2015)
Get full text
Journal Article
Discovery of INCB10820/PF-4178903, a potent, selective, and orally bioavailable dual CCR2 and CCR5 antagonist
Zheng, Changsheng, Cao, Ganfeng, Xia, Michael, Feng, Hao, Glenn, Joseph, Anand, Rajan, Zhang, Ke, Huang, Taisheng, Wang, Anlai, Kong, Ling, Li, Mei, Galya, Laurine, Hughes, Robert O., Devraj, Rajesh, Morton, Phillip A., Rogier, D. Joseph, Covington, Maryanne, Baribaud, Fred, Shin, Niu, Scherle, Peggy, Diamond, Sharon, Yeleswaram, Swamy, Vaddi, Kris, Newton, Robert, Hollis, Greg, Friedman, Steven, Metcalf, Brian, Xue, Chu-Biao
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
Published in Bioorganic & medicinal chemistry letters (01.03.2011)
Get full text
Journal Article
Number preferences in lotteries
Wang, Tong V., van Loon, Rogier J.D. Potter, van den Assem, Martijn J., van Dolder, Dennie
Published in Judgment and Decision Making (01.05.2016)
Published in Judgment and Decision Making (01.05.2016)
Get full text
Journal Article
Do Survey Probabilities Match Financial Market Beliefs?
Lumsdaine, Robin L, van Loon, Rogier J D Potter
Published in The journal of behavioral finance (01.01.2018)
Published in The journal of behavioral finance (01.01.2018)
Get full text
Journal Article
Design and synthesis of novel CCR2 antagonists: Investigation of non-aryl/heteroaryl binding motifs
Trujillo, John I., Huang, Wei, Hughes, Robert O., Joseph Rogier, D., Turner, Steven R., Devraj, Rajesh, Morton, Philip A., Xue, Chu-Biao, Chao, Ganfeng, Covington, Maryanne B., Newton, Robert C., Metcalf, Brian
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Get full text
Journal Article
Investigation of the pyrazinones as PDE5 inhibitors: Evaluation of regioisomeric projections into the solvent region
Hughes, Robert O., Maddux, Todd, Joseph Rogier, D., Lu, Sharon, Walker, John K., Jon Jacobsen, E., Rumsey, Jeanne M., Zheng, Yi, MacInnes, Alan, Bond, Brian R., Han, Seungil
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Published in Bioorganic & medicinal chemistry letters (01.11.2011)
Get full text
Journal Article
Synthesis and Biological Evaluation of the 1,5-Diarylpyrazole Class of Cyclooxygenase-2 Inhibitors: Identification of 4-[5-(4-Methylphenyl)-3- (trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)
Penning, Thomas D, Talley, John J, Bertenshaw, Stephen R, Carter, Jeffery S, Collins, Paul W, Docter, Stephen, Graneto, Matthew J, Lee, Len F, Malecha, James W, Miyashiro, Julie M, Rogers, Roland S, Rogier, D. J, Yu, Stella S, Anderson, Gary D, Burton, Earl G, Cogburn, J. Nita, Gregory, Susan A, Koboldt, Carol M, Perkins, William E, Seibert, Karen, Veenhuizen, Amy W, Zhang, Yan Y, Isakson, Peter C
Published in Journal of medicinal chemistry (25.04.1997)
Published in Journal of medicinal chemistry (25.04.1997)
Get full text
Journal Article
Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors
Owen, Dafydd R., Walker, John K., Jon Jacobsen, E., Freskos, John N., Hughes, Robert O., Brown, David L., Bell, Andrew S., Brown, David G., Phillips, Christopher, Mischke, Brent V., Molyneaux, John M., Fobian, Yvette M., Heasley, Steve E., Moon, Joseph B., Stallings, William C., Joseph Rogier, D., Fox, David N.A., Palmer, Michael J., Ringer, Tracy, Rodriquez-Lens, Margarita, Cubbage, Jerry W., Blevis-Bal, Radhika M., Benson, Alan G., Acker, Brad A., Maddux, Todd M., Tollefson, Michael B., Bond, Brian R., MacInnes, Alan, Yu, Yung
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Get full text
Journal Article
Discovery of INCB8761/PF-4136309, a Potent, Selective, and Orally Bioavailable CCR2 Antagonist
Xue, Chu-Biao, Wang, Anlai, Han, Qi, Zhang, Yingxin, Cao, Ganfeng, Feng, Hao, Huang, Taisheng, Zheng, Changsheng, Xia, Michael, Zhang, Ke, Kong, Lingquan, Glenn, Joseph, Anand, Rajan, Meloni, David, Robinson, D. J, Shao, Lixin, Storace, Lou, Li, Mei, Hughes, Robert O, Devraj, Rajesh, Morton, Philip A, Rogier, D. Joseph, Covington, Maryanne, Scherle, Peggy, Diamond, Sharon, Emm, Tom, Yeleswaram, Swamy, Contel, Nancy, Vaddi, Kris, Newton, Robert, Hollis, Greg, Metcalf, Brian
Published in ACS medicinal chemistry letters (08.12.2011)
Published in ACS medicinal chemistry letters (08.12.2011)
Get full text
Journal Article
Optimization of the aminopyridopyrazinones class of PDE5 inhibitors: Discovery of 3-[( trans-4-hydroxycyclohexyl)amino]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4- b]pyrazin-2(1 H)-one
Hughes, Robert O., Walker, John K., Joseph Rogier, D., Heasley, Steve E., Blevis-Bal, Rhadika M., Benson, Alan G., Jon Jacobsen, E., Cubbage, Jerry W., Fobian, Yvette M., Owen, Dafydd R., Freskos, John N., Molyneaux, John M., Brown, David L., Acker, Brad A., Maddux, Todd M., Tollefson, Mike B., Moon, Joseph B., Mischke, Brent V., Rumsey, Jeanne M., Zheng, Yi, MacInnes, Alan, Bond, Brian R., Yu, Ying
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
Published in Bioorganic & medicinal chemistry letters (01.09.2009)
Get full text
Journal Article
Discovery of ((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-4-ylamino)cyclopentyl)(4-(5-(trifluoromethyl)pyridazin-3-yl)piperazin-1-yl)methanone, PF-4254196, a CCR2 antagonist with an improved cardiovascular profile
Hughes, Robert O, Rogier, D.J, Devraj, Rajesh, Zheng, Changsheng, Cao, Ganfeng, Feng, Hao, Xia, Michael, Anand, Rajan, Xing, Li, Glenn, Joseph, Zhang, Ke, Covington, Maryanne, Morton, Philip A, Hutzler, J. Matthew, Davis, John W., II, Scherle, Peggy, Baribaud, Fred, Bahinski, Anthony, Mo, Zun-Li, Newton, Robert, Metcalf, Brian, Xue, Chu-Biao
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
Get full text
Journal Article
Design, Synthesis, and Biological Evaluation of 3-[4-(2-Hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a Potent, Orally Active, Brain Penetrant Inhibitor of Phosphodiesterase 5 (PDE5)
Hughes, Robert O, Rogier, D. Joseph, Jacobsen, E. Jon, Walker, John K, MacInnes, Alan, Bond, Brian R, Zhang, Lena L, Yu, Ying, Zheng, Yi, Rumsey, Jeanne M, Walgren, Jennie L, Curtiss, Sandra W, Fobian, Yvette M, Heasley, Steven E, Cubbage, Jerry W, Moon, Joseph B, Brown, David L, Acker, Brad A, Maddux, Todd M, Tollefson, Mike B, Mischke, Brent V, Owen, Dafydd R, Freskos, John N, Molyneaux, John M, Benson, Alan G, Blevis-Bal, Rhadika M
Published in Journal of medicinal chemistry (25.03.2010)
Published in Journal of medicinal chemistry (25.03.2010)
Get full text
Journal Article
Investigation of aminopyridiopyrazinones as PDE5 inhibitors: Evaluation of modifications to the central ring system
Hughes, Robert O., Walker, John K., Cubbage, Jerry W., Fobian, Yvette M., Rogier, D. Joseph, Heasley, Steve E., Blevis-Bal, Rhadika M., Benson, Alan G., Owen, Dafydd R., Jacobsen, E. Jon, Freskos, John N., Molyneaux, John M., Brown, David L., Stallings, William C., Acker, Brad A., Maddux, Todd M., Tollefson, Mike B., Williams, Jennifer M., Moon, Joseph B., Mischke, Brent V., Rumsey, Jeanne M., Zheng, Yi, MacInnes, Alan, Bond, Brian R., Yu, Ying
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Get full text
Journal Article
Effects of acetylsalicylic acid treatment on thyroid hormones, prolactins, and the stress response of tilapia (Oreochromis mossambicus)
van Anholt, Rogier D, Spanings, Tom, Koven, William, Bonga, Sjoerd E. Wendelaar
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.11.2003)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.11.2003)
Get full text
Journal Article
Incentives, performance and choking in darts
Klein Teeselink, Bouke, Potter van Loon, Rogier J.D., van den Assem, Martijn J., van Dolder, Dennie
Published in Journal of economic behavior & organization (01.01.2020)
Published in Journal of economic behavior & organization (01.01.2020)
Get full text
Journal Article
4,5-Diaryloxazole inhibitors of cyclooxygenase-2 (COX-2)
Talley, John J., Bertenshaw, Stephen R., Brown, David L., Carter, Jeffery S., Graneto, Mathew J., Koboldt, Carol M., Masferrer, Jaime L., Norman, Bryan H., Rogier Jr, D. Joseph, Zweifel, Ben S., Seibert, Karen
Published in Medicinal research reviews (01.05.1999)
Published in Medicinal research reviews (01.05.1999)
Get full text
Journal Article
Patient Related Determinants of the Administration of Continuous Palliative Sedation in Hospices and Palliative Care Units: A Prospective, Multicenter, Observational Study
van Deijck, Rogier H.P.D., MD, Hasselaar, Jeroen G.J., MSc, Verhagen, Stans C.A.H.H.V.M., MD, PhD, Vissers, Kris C.P., MD, PhD, Koopmans, Raymond T.C.M., MD, PhD
Published in Journal of pain and symptom management (01.05.2016)
Published in Journal of pain and symptom management (01.05.2016)
Get full text
Journal Article