Oxetanes as Versatile Elements in Drug Discovery and Synthesis
Burkhard, Johannes A., Wuitschik, Georg, Rogers-Evans, Mark, Müller, Klaus, Carreira, Erick M.
Published in Angewandte Chemie International Edition (22.11.2010)
Published in Angewandte Chemie International Edition (22.11.2010)
Get full text
Journal Article
NF‐κB activation in astrocytes drives a stage‐specific beneficial neuroimmunological response in ALS
Ouali Alami, Najwa, Schurr, Christine, Olde Heuvel, Florian, Tang, Linyun, Li, Qian, Tasdogan, Alpaslan, Kimbara, Atsushi, Nettekoven, Matthias, Ottaviani, Giorgio, Raposo, Catarina, Röver, Stephan, Rogers‐Evans, Mark, Rothenhäusler, Benno, Ullmer, Christoph, Fingerle, Jürgen, Grether, Uwe, Knuesel, Irene, Boeckers, Tobias M, Ludolph, Albert, Wirth, Thomas, Roselli, Francesco, Baumann, Bernd
Published in The EMBO journal (15.08.2018)
Published in The EMBO journal (15.08.2018)
Get full text
Journal Article
Oxetanes as Promising Modules in Drug Discovery
Wuitschik, Georg, Rogers-Evans, Mark, Müller, Klaus, Fischer, Holger, Wagner, Björn, Schuler, Franz, Polonchuk, Liudmila, Carreira, Erick M.
Published in Angewandte Chemie International Edition (27.11.2006)
Published in Angewandte Chemie International Edition (27.11.2006)
Get full text
Journal Article
Synthesis and Stability of Oxetane Analogs of Thalidomide and Lenalidomide
Burkhard, Johannes A, Wuitschik, Georg, Plancher, Jean-Marc, Rogers-Evans, Mark, Carreira, Erick M
Published in Organic letters (06.09.2013)
Published in Organic letters (06.09.2013)
Get full text
Journal Article
Spirocyclic Oxetanes: Synthesis and Properties
Wuitschik, Georg, Rogers-Evans, Mark, Buckl, Andreas, Bernasconi, Maurizio, Märki, Moritz, Godel, Thierry, Fischer, Holger, Wagner, Björn, Parrilla, Isabelle, Schuler, Franz, Schneider, Josef, Alker, André, Schweizer, W. Bernd, Müller, Klaus, Carreira, Erick M.
Published in Angewandte Chemie International Edition (02.06.2008)
Published in Angewandte Chemie International Edition (02.06.2008)
Get full text
Journal Article
Discovery of Highly Selective Brain-Penetrant Vasopressin 1a Antagonists for the Potential Treatment of Autism via a Chemogenomic and Scaffold Hopping Approach
Ratni, Hasane, Rogers-Evans, Mark, Bissantz, Caterina, Grundschober, Christophe, Moreau, Jean-Luc, Schuler, Franz, Fischer, Holger, Alvarez Sanchez, Ruben, Schnider, Patrick
Published in Journal of medicinal chemistry (12.03.2015)
Published in Journal of medicinal chemistry (12.03.2015)
Get full text
Journal Article
Selective Cannabinoid 2 Receptor Agonists as Potential Therapeutic Drugs for the Treatment of Endotoxin-Induced Uveitis
Porter, Richard Frederick, Szczesniak, Anna-Maria, Toguri, James Thomas, Gebremeskel, Simon, Johnston, Brent, Lehmann, Christian, Fingerle, Jürgen, Rothenhäusler, Benno, Perret, Camille, Rogers-Evans, Mark, Kimbara, Atsushi, Nettekoven, Matthias, Guba, Wolfgang, Grether, Uwe, Ullmer, Christoph, Kelly, Melanie E M
Published in Molecules (Basel, Switzerland) (13.09.2019)
Published in Molecules (Basel, Switzerland) (13.09.2019)
Get full text
Journal Article
RG7774 (Vicasinabin), an orally bioavailable cannabinoid receptor 2 (CB2R) agonist, decreases retinal vascular permeability, leukocyte adhesion, and ocular inflammation in animal models
Grether, Uwe, Foxton, Richard H, Gruener, Sabine, Korn, Claudia, Kimbara, Atsushi, Osterwald, Anja, Zirwes, Elisabeth, Uhles, Sabine, Thoele, Janina, Colé, Nadine, Rogers-Evans, Mark, Röver, Stephan, Nettekoven, Matthias, Martin, Rainer E, Adam, Jean-Michel, Fingerle, Jürgen, Bissantz, Caterina, Guba, Wolfgang, Alker, André, Szczesniak, Anna M, Porter, Ross F, Toguri, Tom J, Revelant, Franco, Poirier, Agnès, Perret, Camille, Winther, Lotte, Caruso, Antonello, Fezza, Filomena, Maccarrone, Mauro, Kelly, Melanie E M, Fauser, Sascha, Ullmer, Christoph
Published in Frontiers in pharmacology (12.07.2024)
Published in Frontiers in pharmacology (12.07.2024)
Get full text
Journal Article
Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists as Potential Treatment for Inflammatory Kidney Diseases
Nettekoven, Matthias, Adam, Jean-Michel, Bendels, Stefanie, Bissantz, Catarina, Fingerle, Jürgen, Grether, Uwe, Grüner, Sabine, Guba, Wolfgang, Kimbara, Atsushi, Ottaviani, Giorgio, Püllmann, Bernd, Rogers-Evans, Mark, Röver, Stephan, Rothenhäusler, Benno, Schmitt, Sebastien, Schuler, Franz, Schulz-Gasch, Tanja, Ullmer, Christoph
Published in ChemMedChem (19.01.2016)
Published in ChemMedChem (19.01.2016)
Get full text
Journal Article
BACE1 inhibitors: A head group scan on a series of amides
Woltering, Thomas J., Wostl, Wolfgang, Hilpert, Hans, Rogers-Evans, Mark, Pinard, Emmanuel, Mayweg, Alexander, Göbel, Martin, Banner, David W., Benz, Jörg, Travagli, Massimiliano, Pollastrini, Martina, Marconi, Guido, Gabellieri, Emanuele, Guba, Wolfgang, Mauser, Harald, Andreini, Matteo, Jacobsen, Helmut, Power, Eoin, Narquizian, Robert
Published in Bioorganic & medicinal chemistry letters (15.07.2013)
Published in Bioorganic & medicinal chemistry letters (15.07.2013)
Get full text
Journal Article
Behavioral analysis through the lifespan of disc1 mutant zebrafish identifies defects in sensorimotor transformation
Pluimer, Brock R., Harrison, Devin L., Boonyavairoje, Chanon, Prinssen, Eric P., Rogers-Evans, Mark, Peterson, Randall T., Thyme, Summer B., Nath, Anjali K.
Published in iScience (21.07.2023)
Published in iScience (21.07.2023)
Get full text
Journal Article
Adventures in drug-like chemistry space: from oxetanes to spiroazetidines and beyond
Rogers-Evans, Mark, Knust, Henner, Plancher, Jean-Marc, Carreira, Erick M, Wuitschik, George, Burkhard, Johannes, Li, Dong B, Guérot, Carine
Published in Chimia (01.01.2014)
Published in Chimia (01.01.2014)
Get full text
Journal Article
Inside Cover: Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists as Potential Treatment for Inflammatory Kidney Diseases (ChemMedChem 2/2016)
Nettekoven, Matthias, Adam, Jean-Michel, Bendels, Stefanie, Bissantz, Catarina, Fingerle, Jürgen, Grether, Uwe, Grüner, Sabine, Guba, Wolfgang, Kimbara, Atsushi, Ottaviani, Giorgio, Püllmann, Bernd, Rogers-Evans, Mark, Röver, Stephan, Rothenhäusler, Benno, Schmitt, Sebastien, Schuler, Franz, Schulz-Gasch, Tanja, Ullmer, Christoph
Published in ChemMedChem (01.01.2016)
Published in ChemMedChem (01.01.2016)
Get full text
Journal Article
[45-d] NOVEL TRIAZOLO[45-D]PYRIMIDINE DERIVATIVES
KIMBARA ATSUSHI, ROGERS EVANS MARK, ROEVER STEPHAN, SCHMITT SEBASTIEN, GRETHER UWE, NETTEKOVEN MATTHIAS
Year of Publication 18.10.2022
Get full text
Year of Publication 18.10.2022
Patent
CB2 PURINE DERIVATIVES AS CB2 RECEPTOR AGONISTS
KIMBARA ATSUSHI, BENDELS STEFANIE, ROGERS EVANS MARK, ROEVER STEPHAN, SCHULZ GASCH TANJA, GRETHER UWE, NETTEKOVEN MATTHIAS
Year of Publication 01.12.2021
Get full text
Year of Publication 01.12.2021
Patent
[45-d] NOVEL TRIAZOLO[45-D]PYRIMIDINE DERIVATIVES
KIMBARA ATSUSHI, ROGERS EVANS MARK, ROEVER STEPHAN, SCHMITT SEBASTIEN, GRETHER UWE, NETTEKOVEN MATTHIAS
Year of Publication 21.06.2021
Get full text
Year of Publication 21.06.2021
Patent