The Candida glabrata Upc2A transcription factor is a global regulator of antifungal drug resistance pathways
Vu, Bao Gia, Stamnes, Mark A, Li, Yu, Rogers, P David, Moye-Rowley, W Scott
Published in PLoS genetics (30.09.2021)
Published in PLoS genetics (30.09.2021)
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Gain-of-Function Mutations in UPC2 Are a Frequent Cause of ERG11 Upregulation in Azole-Resistant Clinical Isolates of Candida albicans
Flowers, Stephanie A, Barker, Katherine S, Berkow, Elizabeth L, Toner, Geoffrey, Chadwick, Sean G, Gygax, Scott E, Morschhäuser, Joachim, Rogers, P David
Published in Eukaryotic Cell (01.10.2012)
Published in Eukaryotic Cell (01.10.2012)
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Journal Article
Mutations in TAC1B : a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris
Rybak, Jeffrey M, Muñoz, José F, Barker, Katherine S, Parker, Josie E, Esquivel, Brooke D, Berkow, Elizabeth L, Lockhart, Shawn R, Gade, Lalitha, Palmer, Glen E, White, Theodore C, Kelly, Steve L, Cuomo, Christina A, Rogers, P David
Published in mBio (12.05.2020)
Published in mBio (12.05.2020)
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Journal Article
Emerging threat of triazole-resistant Aspergillus fumigatus
Rybak, Jeffrey M, Fortwendel, Jarrod R, Rogers, P David
Published in Journal of antimicrobial chemotherapy (01.04.2019)
Published in Journal of antimicrobial chemotherapy (01.04.2019)
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Mutations in the multi-drug resistance regulator MRR1, followed by loss of heterozygosity, are the main cause of MDR1 overexpression in fluconazole-resistant Candida albicans strains
Dunkel, Nico, Blaß, Julia, Rogers, P. David, Morschhäuser, Joachim
Published in Molecular microbiology (01.08.2008)
Published in Molecular microbiology (01.08.2008)
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Contribution of Clinically Derived Mutations in the Gene Encoding the Zinc Cluster Transcription Factor Mrr2 to Fluconazole Antifungal Resistance and CDR1 Expression in Candida albicans
Nishimoto, Andrew T, Zhang, Qing, Hazlett, Brandon, Morschhäuser, Joachim, Rogers, P David
Published in Antimicrobial agents and chemotherapy (01.05.2019)
Published in Antimicrobial agents and chemotherapy (01.05.2019)
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Journal Article
The transcription factor Mrr1p controls expression of the MDR1 efflux pump and mediates multidrug resistance in Candida albicans
Morschhäuser, Joachim, Barker, Katherine S, Liu, Teresa T, BlaB-Warmuth, Julia, Homayouni, Ramin, Rogers, P David
Published in PLoS pathogens (01.11.2007)
Published in PLoS pathogens (01.11.2007)
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In Vitro Activities of the Novel Investigational Tetrazoles VT-1161 and VT-1598 Compared to the Triazole Antifungals against Azole-Resistant Strains and Clinical Isolates of Candida albicans
Nishimoto, Andrew T, Wiederhold, Nathan P, Flowers, Stephanie A, Zhang, Qing, Kelly, Steven L, Morschhäuser, Joachim, Yates, Christopher M, Hoekstra, William J, Schotzinger, Robert J, Garvey, Edward P, Rogers, P David
Published in Antimicrobial agents and chemotherapy (01.06.2019)
Published in Antimicrobial agents and chemotherapy (01.06.2019)
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Journal Article
A Hyperactive Form of the Zinc Cluster Transcription Factor Stb5 Causes YOR1 Overexpression and Beauvericin Resistance in Candida albicans
Ramírez-Zavala, Bernardo, Manz, Hannah, Englert, Frank, Rogers, P David, Morschhäuser, Joachim
Published in Antimicrobial agents and chemotherapy (01.12.2018)
Published in Antimicrobial agents and chemotherapy (01.12.2018)
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The sterol C-24 methyltransferase encoding gene, erg6, is essential for viability of Aspergillus species
Xie, Jinhong, Rybak, Jeffrey M., Martin-Vicente, Adela, Guruceaga, Xabier, Thorn, Harrison I., Nywening, Ashley V., Ge, Wenbo, Parker, Josie E., Kelly, Steven L., Rogers, P. David, Fortwendel, Jarrod R.
Published in Nature communications (20.05.2024)
Published in Nature communications (20.05.2024)
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A secondary mechanism of action for triazole antifungals in Aspergillus fumigatus mediated by hmg1
Rybak, Jeffrey M., Xie, Jinhong, Martin-Vicente, Adela, Guruceaga, Xabier, Thorn, Harrison I., Nywening, Ashley V., Ge, Wenbo, Souza, Ana C. O., Shetty, Amol C., McCracken, Carrie, Bruno, Vincent M., Parker, Josie E., Kelly, Steven L., Snell, Hannah M., Cuomo, Christina A., Rogers, P. David, Fortwendel, Jarrod R.
Published in Nature communications (29.04.2024)
Published in Nature communications (29.04.2024)
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Journal Article
An A643T Mutation in the Transcription Factor Upc2p Causes Constitutive ERG11 Upregulation and Increased Fluconazole Resistance in Candida albicans
HEILMANN, Clemens J, SCHNEIDER, Sabrina, BARKER, Katherine S, ROGERS, P. David, MORSCHHÄUSER, Joachim
Published in Antimicrobial Agents and Chemotherapy (01.01.2010)
Published in Antimicrobial Agents and Chemotherapy (01.01.2010)
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hapE and hmg1 Mutations Are Drivers of cyp51A -Independent Pan-Triazole Resistance in an Aspergillus fumigatus Clinical Isolate
Souza, Ana C O, Ge, Wenbo, Wiederhold, Nathan P, Rybak, Jeffrey M, Fortwendel, Jarrod R, Rogers, P David
Published in Microbiology spectrum (15.06.2023)
Published in Microbiology spectrum (15.06.2023)
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