Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?)
Roep, Bart O., Thomaidou, Sofia, van Tienhoven, René, Zaldumbide, Arnaud
Published in Nature reviews. Endocrinology (01.03.2021)
Published in Nature reviews. Endocrinology (01.03.2021)
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Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study
de Groot, Pieter F, Belzer, Clara, Aydin, Ömrüm, Levin, Evgeni, Levels, Johannes H, Aalvink, Steven, Boot, Fransje, Holleman, Frits, van Raalte, Daniël H, Scheithauer, Torsten P, Simsek, Suat, Schaap, Frank G, Olde Damink, Steven W M, Roep, Bart O, Hoekstra, Joost B, de Vos, Willem M, Nieuwdorp, Max
Published in PloS one (06.12.2017)
Published in PloS one (06.12.2017)
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Islet stress, degradation and autoimmunity
Thomaidou, Sofia, Zaldumbide, Arnaud, Roep, Bart O.
Published in Diabetes, obesity & metabolism (01.09.2018)
Published in Diabetes, obesity & metabolism (01.09.2018)
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Immune checkpoint inhibitors and type 1 diabetes mellitus: a case report and systematic review
de Filette, Jeroen M K, Pen, Joeri J, Decoster, Lore, Vissers, Thomas, Bravenboer, Bert, Van der Auwera, Bart J, Gorus, Frans K, Roep, Bart O, Aspeslagh, Sandrine, Neyns, Bart, Velkeniers, Brigitte, Kharagjitsingh, Aan V
Published in European journal of endocrinology (01.09.2019)
Published in European journal of endocrinology (01.09.2019)
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Journal Article
Antigen-based immune modulation therapy for type 1 diabetes: the era of precision medicine
Roep, Bart O, Wheeler, Daniel C S, Peakman, Mark
Published in The lancet. Diabetes & endocrinology (01.01.2019)
Published in The lancet. Diabetes & endocrinology (01.01.2019)
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Journal Article
Low risk for diabetic complications in type 1 diabetes patients carrying a protective insulin gene variant
van Tienhoven, René, Vu, Anh Nguyet, Kaddis, John S, Roep, Bart O
Published in PloS one (26.01.2023)
Published in PloS one (26.01.2023)
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Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells
Furuyama, Kenichiro, Chera, Simona, van Gurp, Léon, Oropeza, Daniel, Ghila, Luiza, Damond, Nicolas, Vethe, Heidrun, Paulo, Joao A., Joosten, Antoinette M., Berney, Thierry, Bosco, Domenico, Dorrell, Craig, Grompe, Markus, Ræder, Helge, Roep, Bart O., Thorel, Fabrizio, Herrera, Pedro L.
Published in Nature (London) (07.03.2019)
Published in Nature (London) (07.03.2019)
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Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes
Kracht, Maria J L, van Lummel, Menno, Nikolic, Tatjana, Joosten, Antoinette M, Laban, Sandra, van der Slik, Arno R, van Veelen, Peter A, Carlotti, Françoise, de Koning, Eelco J P, Hoeben, Rob C, Zaldumbide, Arnaud, Roep, Bart O
Published in Nature medicine (01.04.2017)
Published in Nature medicine (01.04.2017)
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Journal Article
The challenge of modulating β-cell autoimmunity in type 1 diabetes
Atkinson, Mark A, Roep, Bart O, Posgai, Amanda, Wheeler, Daniel C S, Peakman, Mark
Published in The lancet. Diabetes & endocrinology (01.01.2019)
Published in The lancet. Diabetes & endocrinology (01.01.2019)
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Journal Article
Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes
Battaglia, Manuela, Ahmed, Simi, Anderson, Mark S, Atkinson, Mark A, Becker, Dorothy, Bingley, Polly J, Bosi, Emanuele, Brusko, Todd M, DiMeglio, Linda A, Evans-Molina, Carmella, Gitelman, Stephen E, Greenbaum, Carla J, Gottlieb, Peter A, Herold, Kevan C, Hessner, Martin J, Knip, Mikael, Jacobsen, Laura, Krischer, Jeffrey P, Long, S Alice, Lundgren, Markus, McKinney, Eoin F, Morgan, Noel G, Oram, Richard A, Pastinen, Tomi, Peters, Michael C, Petrelli, Alessandra, Qian, Xiaoning, Redondo, Maria J, Roep, Bart O, Schatz, Desmond, Skibinski, David, Peakman, Mark
Published in Diabetes care (01.01.2020)
Published in Diabetes care (01.01.2020)
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Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients
Coppieters, Ken T, Dotta, Francesco, Amirian, Natalie, Campbell, Peter D, Kay, Thomas W H, Atkinson, Mark A, Roep, Bart O, von Herrath, Matthias G
Published in The Journal of experimental medicine (16.01.2012)
Published in The Journal of experimental medicine (16.01.2012)
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Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis
Leete, Pia, Oram, Richard A., McDonald, Timothy J., Shields, Beverley M., Ziller, Clemens, Hattersley, Andrew T., Richardson, Sarah J., Morgan, Noel G.
Published in Diabetologia (01.06.2020)
Published in Diabetologia (01.06.2020)
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