Tricyclic Compounds Containing Nonenolizable Cyano Enones. A Novel Class of Highly Potent Anti-Inflammatory and Cytoprotective Agents
Honda, Tadashi, Yoshizawa, Hidenori, Sundararajan, Chitra, David, Emilie, Lajoie, Marc J, Favaloro, Frank G, Janosik, Tomasz, Su, Xiaobo, Honda, Yukiko, Roebuck, Bill D, Gribble, Gordon W
Published in Journal of medicinal chemistry (24.03.2011)
Published in Journal of medicinal chemistry (24.03.2011)
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Journal Article
Aldo‐keto reductase‐7A protects liver cells and tissues from acetaminophen‐induced oxidative stress and hepatotoxicity
Ahmed, Munzir M.E., Wang, Tao, Luo, Yu, Ye, Shuilong, Wu, Qiao, Guo, Zongsheng, Roebuck, Bill D., Sutter, Thomas R., Yang, James Y.
Published in Hepatology (Baltimore, Md.) (01.10.2011)
Published in Hepatology (Baltimore, Md.) (01.10.2011)
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Just for fun
Roebuck, Bill D
Published in Science (American Association for the Advancement of Science) (07.02.2020)
Published in Science (American Association for the Advancement of Science) (07.02.2020)
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A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin
Liby, Karen, Yore, Mark M, Roebuck, Bill D, Baumgartner, Karen J, Honda, Tadashi, Sundararajan, Chitra, Yoshizawa, Hidenori, Gribble, Gordon W, Williams, Charlotte R, Risingsong, Renee, Royce, Darlene B, Dinkova-Kostova, Albena T, Stephenson, Katherine K, Egner, Patricia A, Yates, Melinda S, Groopman, John D, Kensler, Thomas W, Sporn, Michael B
Published in Cancer research (Chicago, Ill.) (15.08.2008)
Published in Cancer research (Chicago, Ill.) (15.08.2008)
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Journal Article
Aflatoxin: a 50-year odyssey of mechanistic and translational toxicology
Kensler, Thomas W, Roebuck, Bill D, Wogan, Gerald N, Groopman, John D
Published in Toxicological sciences (01.03.2011)
Published in Toxicological sciences (01.03.2011)
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Journal Article
Protection Against Aflatoxin B1-Induced Cytotoxicity by Expression of the Cloned Aflatoxin B1-Aldehyde Reductases Rat AKR7A1 and Human AKR7A3
Bodreddigari, Sridevi, Jones, Laundette Knight, Egner, Patricia A, Sutter, Carrie Hayes, Roebuck, Bill D, Guengerich, F. Peter, Kensler, Thomas W, Sutter, Thomas R
Published in Chemical research in toxicology (01.05.2008)
Published in Chemical research in toxicology (01.05.2008)
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Quantification of Urinary Aflatoxin B1 Dialdehyde Metabolites Formed by Aflatoxin Aldehyde Reductase Using Isotope Dilution Tandem Mass Spectrometry
Johnson, Denise N, Egner, Patricia A, OBrian, Greg, Glassbrook, Norman, Roebuck, Bill D, Sutter, Thomas R, Payne, Gary A, Kensler, Thomas W, Groopman, John D
Published in Chemical research in toxicology (01.03.2008)
Published in Chemical research in toxicology (01.03.2008)
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Journal Article
Profound changes in miRNA expression during cancer initiation by aflatoxin B1 and their abrogation by the chemopreventive triterpenoid CDDO‐Im
Livingstone, Merricka C., Johnson, Natalie M., Roebuck, Bill D., Kensler, Thomas W., Groopman, John D.
Published in Molecular carcinogenesis (01.11.2017)
Published in Molecular carcinogenesis (01.11.2017)
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Complete Protection against Aflatoxin B1-Induced Liver Cancer with a Triterpenoid: DNA Adduct Dosimetry, Molecular Signature, and Genotoxicity Threshold
JOHNSON, Natalie M, EGNER, Patricia A, BAXTER, Victoria K, SPORN, Michael B, WIBLE, Ryan S, SUTTER, Thomas R, GROOPMAN, John D, KENSLER, Thomas W, ROEBUCK, Bill D
Published in Cancer prevention research (Philadelphia, Pa.) (01.07.2014)
Published in Cancer prevention research (Philadelphia, Pa.) (01.07.2014)
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Abstract 1083: Temporal trends in microRNAs during subchronic aflatoxin dosing and modulation by the chemopreventive oleane triterpenoid, CDDO-Im
Livingstone, Merricka C., Roebuck, Bill D., Johnson, Natalie M., Kensler, Thomas W., Groopman, John D.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Profound changes in miRNA expression during cancer initiation by aflatoxin B 1 and their abrogation by the chemopreventive triterpenoid CDDO-Im
Livingstone, Merricka C, Johnson, Natalie M, Roebuck, Bill D, Kensler, Thomas W, Groopman, John D
Published in Molecular carcinogenesis (01.11.2017)
Published in Molecular carcinogenesis (01.11.2017)
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Journal Article
Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat
Simonich, Michael T., Egner, Patricia A., Roebuck, Bill D., Orner, Gayle A., Jubert, Carole, Pereira, Cliff, Groopman, John D., Kensler, Thomas W., Dashwood, Roderick H., Williams, David E., Bailey, George S.
Published in Carcinogenesis (New York) (01.06.2007)
Published in Carcinogenesis (New York) (01.06.2007)
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Journal Article
Natural chlorophyll inhibits aflatoxin B[sub]1-induced multi-organ carcinogenesis in the rat
Simonich, Michael T, Egner, Patricia A, Roebuck, Bill D, Orner, Gayle A, Jubert, Carole, Pereira, Cliff, Groopman, John D, Kensler, Thomas W, Dashwood, Roderick H, Williams, David E, Bailey, George S
Published in Carcinogenesis (New York) (01.06.2007)
Published in Carcinogenesis (New York) (01.06.2007)
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Lactone Metabolite Common to the Carcinogens Dioxane, Diethylene Glycol, and N-Nitrosomorpholine: Aqueous Chemistry and Failure to Mediate Liver Carcinogenesis in the F344 Rat
Koissi, Niangoran, Shah, Niti H, Ginevan, Brandon, Eck, William S, Roebuck, Bill D, Fishbein, James C
Published in Chemical research in toxicology (21.05.2012)
Published in Chemical research in toxicology (21.05.2012)
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Identification of Aflatoxin M1-N7-Guanine in Liver and Urine of Tree Shrews and Rats Following Administration of Aflatoxin B1
Egner, Patricia A, Yu, Xiang, Johnson, Jesse K, Nathasingh, Christopher K, Groopman, John D, Kensler, Thomas W, Roebuck, Bill D
Published in Chemical research in toxicology (15.09.2003)
Published in Chemical research in toxicology (15.09.2003)
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Journal Article
Reduction of aflatoxin B1 adduct biomarkers by oltipraz in the tree shrew (Tupaia belangeri chinensis)
YUAN LI, SU, J.-J, QIN, L.-L, EGNER, P. A, WANG, J.-S, GROOPMAN, J. D, KENSLER, T. W, ROEBUCK, B. D
Published in Cancer letters (01.06.2000)
Published in Cancer letters (01.06.2000)
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Transgenic Expression of Aflatoxin Aldehyde Reductase (AKR7A1) Modulates Aflatoxin B1 Metabolism but not Hepatic Carcinogenesis in the Rat
Roebuck, Bill D., Johnson, Denise N., Sutter, Carrie Hayes, Egner, Patricia A., Scholl, Peter F., Friesen, Marlin D., Baumgartner, Karen J., Ware, Nicholas M., Bodreddigari, Sridevi, Groopman, John D., Kensler, Thomas W., Sutter, Thomas R.
Published in Toxicological sciences (01.05.2009)
Published in Toxicological sciences (01.05.2009)
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Chemical genomics of cancer chemopreventive dithiolethiones
Tran, Quynh T., Xu, Lijing, Phan, Vinhthuy, Goodwin, Shirlean B., Rahman, Mostafizur, Jin, Victor X., Sutter, Carrie H., Roebuck, Bill D., Kensler, Thomas W., George, E.Olusegun, Sutter, Thomas R.
Published in Carcinogenesis (New York) (01.03.2009)
Published in Carcinogenesis (New York) (01.03.2009)
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Journal Article
Development of Cancer Chemopreventive Agents: Oltipraz as a Paradigm
Kensler, Thomas W, Groopman, John D, Sutter, Thomas R, Curphey, Thomas J, Roebuck, Bill D
Published in Chemical research in toxicology (01.02.1999)
Published in Chemical research in toxicology (01.02.1999)
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