A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
Garg, Abhishek D, Krysko, Dmitri V, Verfaillie, Tom, Kaczmarek, Agnieszka, Ferreira, Gabriela B, Marysael, Thierry, Rubio, Noemi, Firczuk, Malgorzata, Mathieu, Chantal, Roebroek, Anton J M, Annaert, Wim, Golab, Jakub, de Witte, Peter, Vandenabeele, Peter, Agostinis, Patrizia
Published in The EMBO journal (07.03.2012)
Published in The EMBO journal (07.03.2012)
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Journal Article
Impaired LDL receptor-related protein 1 translocation correlates with improved dyslipidemia and atherosclerosis in apoE-deficient mice
Gordts, Philip L S M, Bartelt, Alexander, Nilsson, Stefan K, Annaert, Wim, Christoffersen, Christina, Nielsen, Lars Bo, Heeren, Joerg, Roebroek, Anton J M
Published in PloS one (06.06.2012)
Published in PloS one (06.06.2012)
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Journal Article
Mutant Lrp1 Knock-In Mice Generated by Recombinase-Mediated Cassette Exchange Reveal Differential Importance of the NPXY Motifs in the Intracellular Domain of LRP1 for Normal Fetal Development
Roebroek, Anton J. M., Reekmans, Sara, Lauwers, Annick, Feyaerts, Nathalie, Smeijers, Liesbet, Hartmann, Dieter
Published in Molecular and Cellular Biology (01.01.2006)
Published in Molecular and Cellular Biology (01.01.2006)
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Journal Article
Loss of Endothelial Furin Leads to Cardiac Malformation and Early Postnatal Death
Kim, WooJin, Essalmani, Rachid, Szumska, Dorota, Creemers, John W M, Roebroek, Anton J M, D'Orleans-Juste, Pedro, Bhattacharya, Shoumo, Seidah, Nabil G, Prat, Annik
Published in Molecular and Cellular Biology (01.09.2012)
Published in Molecular and Cellular Biology (01.09.2012)
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Journal Article
Phenotypic and Biochemical Analyses of BACE1- and BACE2-deficient Mice
Dominguez, Diana, Tournoy, Jos, Hartmann, Dieter, Huth, Tobias, Cryns, Kim, Deforce, Siska, Serneels, Lutgarde, Camacho, Ira Espuny, Marjaux, Els, Craessaerts, Katleen, Roebroek, Anton J.M., Schwake, Michael, D'Hooge, Rudi, Bach, Patricia, Kalinke, Ulrich, Moechars, Dieder, Alzheimer, Christian, Reiss, Karina, Saftig, Paul, De Strooper, Bart
Published in The Journal of biological chemistry (02.09.2005)
Published in The Journal of biological chemistry (02.09.2005)
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Journal Article
Role of furin in granular acidification in the endocrine pancreas: Identification of the V-ATPase subunit Ac45 as a candidate substrate
Louagie, Els, Taylor, Neil A, Flamez, Daisy, Roebroek, Anton J.M, Bright, Nicholas A, Meulemans, Sandra, Quintens, Roel, Herrera, Pedro L, Schuit, Frans, Van de Ven, Wim J.M, Creemers, John W.M
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2008)
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Journal Article
Opposing Effects of Apolipoprotein M on Catabolism of Apolipoprotein B–Containing Lipoproteins and Atherosclerosis
Christoffersen, Christina, Pedersen, Tanja Xenia, Gordts, Philip L.S.M, Roebroek, Anton J.M, Dahlbäck, Björn, Nielsen, Lars Bo
Published in Circulation research (28.05.2010)
Published in Circulation research (28.05.2010)
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Journal Article
Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesis
Reekmans, Sara M., Pflanzner, Thorsten, Gordts, Philip L. S. M., Isbert, Simone, Zimmermann, Pascale, Annaert, Wim, Weggen, Sascha, Roebroek, Anton J. M., Pietrzik, Claus U.
Published in Cellular and molecular life sciences : CMLS (01.01.2010)
Published in Cellular and molecular life sciences : CMLS (01.01.2010)
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Journal Article
LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer’s Disease
Van Gool, Bart, Storck, Steffen E., Reekmans, Sara M., Lechat, Benoit, Gordts, Philip L. S. M., Pradier, Laurent, Pietrzik, Claus U., Roebroek, Anton J. M.
Published in Molecular neurobiology (01.10.2019)
Published in Molecular neurobiology (01.10.2019)
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Journal Article
Limited Redundancy of the Proprotein Convertase Furin in Mouse Liver
Roebroek, Anton J.M., Taylor, Neil A., Louagie, Els, Pauli, Ilse, Smeijers, Liesbeth, Snellinx, An, Lauwers, Annick, Van de Ven, Wim J.M., Hartmann, Dieter, Creemers, John W.M.
Published in The Journal of biological chemistry (17.12.2004)
Published in The Journal of biological chemistry (17.12.2004)
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Journal Article
Pathogenic Aβ production by heterozygous PSEN1 mutations is intrinsic to the mutant protein and not mediated by conformational hindrance of wild-type PSEN1
Kurth, Vanessa, Ogorek, Isabella, Münch, Carolina, Lopez-Rios, Javier, Ousson, Solenne, Lehmann, Sandra, Nieweg, Katja, Roebroek, Anton J.M., Pietrzik, Claus U., Beher, Dirk, Weggen, Sascha
Published in The Journal of biological chemistry (01.08.2023)
Published in The Journal of biological chemistry (01.08.2023)
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Journal Article
LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier
Pflanzner, Thorsten, Janko, Maren C, André-Dohmen, Bettina, Reuss, Stefan, Weggen, Sascha, Roebroek, Anton J.M, Kuhlmann, Christoph R.W, Pietrzik, Claus U
Published in Neurobiology of aging (01.12.2011)
Published in Neurobiology of aging (01.12.2011)
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Journal Article
Mutation in the distal NPxY motif of LRP1 alleviates dietary cholesterol-induced dyslipidemia and tissue inflammation
Jaeschke, Anja, Haller, April, Cash, James G., Nam, Christopher, Igel, Emily, Roebroek, Anton J.M., Hui, David Y.
Published in Journal of lipid research (01.01.2021)
Published in Journal of lipid research (01.01.2021)
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Journal Article
The plasma concentration of HDL-associated apoM is influenced by LDL receptor-mediated clearance of apoB-containing particles
Christoffersen, Christina, Benn, Marianne, Christensen, Pernille M., Gordts, Philip L.S.M., Roebroek, Anton J.M., Frikke-Schmidt, Ruth, Tybjaerg-Hansen, Anne, Dahlbäck, Björn, Nielsen, Lars B.
Published in Journal of lipid research (01.10.2012)
Published in Journal of lipid research (01.10.2012)
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Journal Article
Inactivation of the LRP1 Intracellular NPxYxxL Motif in LDLR-Deficient Mice Enhances Postprandial Dyslipidemia and Atherosclerosis
Gordts, Philip L.S.M, Reekmans, Sara, Lauwers, Annick, Dongen, Amber Van, Verbeek, Leen, Roebroek, Anton J.M
Published in Arteriosclerosis, thrombosis, and vascular biology (01.09.2009)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.09.2009)
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Journal Article
Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule
Petersen, Helle Heibroch, Hilpert, Jan, Militz, Daniel, Zandler, Valerie, Jacobsen, Christian, Roebroek, Anton J M, Willnow, Thomas E
Published in Journal of cell science (01.02.2003)
Published in Journal of cell science (01.02.2003)
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Journal Article
Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin
Roebroek, A J, Umans, L, Pauli, I G, Robertson, E J, van Leuven, F, Van de Ven, W J, Constam, D B
Published in Development (Cambridge) (15.12.1998)
Published in Development (Cambridge) (15.12.1998)
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Journal Article
Knock-in approaches
Roebroek, Anton J M, Gordts, Philip L S M, Reekmans, Sara
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2011)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2011)
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