The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer
Soldi, Raffaella, Ghosh Halder, Tithi, Weston, Alexis, Thode, Trason, Drenner, Kevin, Lewis, Rhonda, Kaadige, Mohan R, Srivastava, Shreyesi, Daniel Ampanattu, Sherin, Rodriguez Del Villar, Ryan, Lang, Jessica, Vankayalapati, Hariprasad, Weissman, Bernard, Trent, Jeffrey M, Hendricks, William P D, Sharma, Sunil
Published in PloS one (10.07.2020)
Published in PloS one (10.07.2020)
Get full text
Journal Article
RNA Origami Nanostructures for Potent and Safe Anticancer Immunotherapy
Qi, Xiaodong, Liu, Xiaowei, Matiski, Lawrence, Rodriguez Del Villar, Ryan, Yip, Theresa, Zhang, Fei, Sokalingam, Sriram, Jiang, Shuoxing, Liu, Li, Yan, Hao, Chang, Yung
Published in ACS nano (28.04.2020)
Published in ACS nano (28.04.2020)
Get full text
Journal Article
The Small Molecule BC-2059 Inhibits Wingless/Integrated (Wnt)-Dependent Gene Transcription in Cancer through Disruption of the Transducin β -Like 1- β -Catenin Protein Complex
Soldi, Raffaella, Halder, Tithi Ghosh, Sampson, Samuel, Vankayalapati, Hariprasad, Weston, Alexis, Thode, Trason, Bhalla, Kapil N, Ng, Serina, Rodriguez Del Villar, Ryan, Drenner, Kevin, Kaadige, Mohan R, Horrigan, Stephen K, Batra, Surinder K, Salgia, Ravi, Sharma, Sunil
Published in The Journal of pharmacology and experimental therapeutics (01.08.2021)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2021)
Get full text
Journal Article
Abstract LB-118: SR8541A is a potent inhibitor of ENPP1 and exhibits dendritic cell mediated antitumor activity
WESTON, ALEXIS S., Thode, Trason G., Rodriguez del Villar, Ryan, Dana, Srikanta, Kasibhatla, Srinivas, Kaadige, Mohan R., Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Get full text
Journal Article
RNA origami nanostructures for potent and safe anti-cancer immunotherapy
Matiski, Lawrence, Qi, Xiaodong, Liu, Xiaowei, del Villar, Ryan Rodriguez, Zhang, Fei, Yan, Hao, Chang, Yung
Published in The Journal of immunology (1950) (01.05.2019)
Published in The Journal of immunology (1950) (01.05.2019)
Get full text
Journal Article
Abstract 3068: Everolimus mediated Radioprotection on surrounding healthy tissue in glioblastoma microbrain models
Halder, Tithi Ghosh, del Villar, Ryan Rodriguez, Lacombe, Jerome, Drenner, Kevin, Ng, Serina, Thode, Trason, Weston, Alexis, Kaadige, Mohan, Soldi, Raffaella, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Get full text
Journal Article
Abstract 1254: Preclinical studies with TGN-1062, a selective and reversible small molecule inhibitor of CDK7
Rodriguez del Villar, Ryan L., Thode, Trason G., Weston, Alexis, Ng, Serina, Soldi, Raffaella, Kaadige, Mohan, Kasibhatla, Srinivas, Chung, Vincent, Chao, Joseph, Von Hoff, Daniel D., Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Get full text
Journal Article
Abstract 3948: Development of bone-targeted Ron inhibitors to treat osseous metastases from breast cancers
Thode, Trason, Fornetti, Jaime, Rodriguez del Villar, Ryan, Weston, Alexis, Ng, Serina, Dana, Srikanta, Soldi, Raffaella, Kaadige, Mohan, Vankayalapati, Hariprasad, Kasibhatla, Srinivas, Welm, Alana, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article
Abstract 2567: Targeting TBL1/β-catenin complex using peptides designed to competitively inhibit aberrant Wnt signaling in cancer
Rheinschmidt, Shelby, Thode, Trason, Sampson, Samuel, Weston, Alexis, Halder, Tithi Ghosh, Ng, Serina, Rodriguez del Villar, Ryan, Kaadige, Mohan, Zernov, Anton, Machluf, Marcelle, Soldi, Raffaella, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article
Abstract 4060: Selective Neoantigens Peptide TILs (snapTILs): A next generation tumor infiltrating lymphocytes (TIL) therapy platform
Halder, Tithi Ghosh, Rheinschmidt, Shelby, Adamson, Sydney, Larson, Anna, Bargenquast, Taylor, Rodriguez del Villar, Ryan, Ng, Serina, Gutowsky, Kate, Weston, Alexis, Thode, Trason, Kaadige, Mohan, Kelley, Erin, Soria-Bustos, Jorge, Giron, Jorge, Altin, John, Soldi, Raffaella, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
Abstract 1048: Synergistic drug combination of LSD1 and ABL2 inhibitors for Ewing's sarcoma identified in an arrayed CRISPR screen approach
Sampson, Samuel, Thode, Trason, Drenner, Kevin, Del Villar, Ryan Rodriguez, Ozols, Annika, Kaadige, Mohan, Weston, Alexis, Ng, Serina, Halder, Tithi Ghosh, Rheinschmidt, Shelby, Anderson, David, Holden, Kevin, Soldi, Raffaella, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article
Abstract 3931: TGN-1062 inhibits CDK7 and augments the effects of gemcitabine and nab-paclitaxel in pancreatic cancer models
Weston, Alexis, Thode, Trason, Rodriguez del Villar, Ryan, Ng, Serina, Sampson, Samuel, Rheinschmidt, Shelby, Halder, Tithi Ghosh, Soldi, Raffaella, Kaadige, Mohan, Kasibhatla, Srinivas, Han, Haiyong, Moser, Justin, Chung, Vincent, Chao, Joseph, Villaflor, Victoria, Von Hoff, Daniel, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article
Abstract 1878: 3D Tumor models in drug discovery for high throughput analysis of immune cell infiltration
Halder, Tithi Ghosh, Rheinschmidt, Shelby, Thode, Trason, Sampson, Samuel, Rodriguez del Villar, Ryan, Ng, Serina, Weston, Alexis, Kaadige, Mohan, Trent, Jeffery, Altin, John, Moser, Justin, Borazanci, Erkut, Gordon, Michael, Larson, Anna, Soldi, Raffaella, Sharma, Sunil
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Get full text
Journal Article
The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer
Soldi, Raffaella, Tithi Ghosh Halder, Weston, Alexis, Thode, Trason, Drenner, Kevin, Lewis, Rhonda, Kaadige, Mohan R, Srivastava, Shreyesi, Sherin Daniel Ampanattu, Rodriguez Del Villar, Ryan, Lang, Jessica D, Hariprasad Vankayalapati, Weissman, Bernard, Trent, Jeffrey, Hendricks, William, Sharma, Sunil
Published in bioRxiv (30.01.2020)
Published in bioRxiv (30.01.2020)
Get full text
Paper