In vivo conditional deletion of HDAC7 reveals its requirement to establish proper B lymphocyte identity and development
Azagra, Alba, Román-González, Lidia, Collazo, Olga, Rodríguez-Ubreva, Javier, de Yébenes, Virginia G, Barneda-Zahonero, Bruna, Rodríguez, Jairo, Castro de Moura, Manuel, Grego-Bessa, Joaquim, Fernández-Duran, Irene, Islam, Abul B M M K, Esteller, Manel, Ramiro, Almudena R, Ballestar, Esteban, Parra, Maribel
Published in The Journal of experimental medicine (14.11.2016)
Published in The Journal of experimental medicine (14.11.2016)
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Prediction of the Progression of Undifferentiated Arthritis to Rheumatoid Arthritis Using DNA Methylation Profiling
Calle‐Fabregat, Carlos, Niemantsverdriet, Ellis, Cañete, Juan D., Li, Tianlu, Helm‐van Mil, Annette H. M., Rodríguez‐Ubreva, Javier, Ballestar, Esteban
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2021)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2021)
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SIRT1/2 orchestrate acquisition of DNA methylation and loss of histone H3 activating marks to prevent premature activation of inflammatory genes in macrophages
Li, Tianlu, Garcia-Gomez, Antonio, Morante-Palacios, Octavio, Ciudad, Laura, Özkaramehmet, Sevgi, Van Dijck, Evelien, Rodríguez-Ubreva, Javier, Vaquero, Alejandro, Ballestar, Esteban
Published in Nucleic acids research (24.01.2020)
Published in Nucleic acids research (24.01.2020)
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Prostaglandin E2 Leads to the Acquisition of DNMT3A-Dependent Tolerogenic Functions in Human Myeloid-Derived Suppressor Cells
Rodríguez-Ubreva, Javier, Català-Moll, Francesc, Obermajer, Nataša, Álvarez-Errico, Damiana, Ramirez, Ricardo N., Company, Carlos, Vento-Tormo, Roser, Moreno-Bueno, Gema, Edwards, Robert P., Mortazavi, Ali, Kalinski, Pawel, Ballestar, Esteban
Published in Cell reports (Cambridge) (03.10.2017)
Published in Cell reports (Cambridge) (03.10.2017)
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Sampling time-dependent artifacts in single-cell genomics studies
Massoni-Badosa, Ramon, Iacono, Giovanni, Moutinho, Catia, Kulis, Marta, Palau, Núria, Marchese, Domenica, Rodríguez-Ubreva, Javier, Ballestar, Esteban, Rodriguez-Esteban, Gustavo, Marsal, Sara, Aymerich, Marta, Colomer, Dolors, Campo, Elias, Julià, Antonio, Martín-Subero, José Ignacio, Heyn, Holger
Published in Genome Biology (11.05.2020)
Published in Genome Biology (11.05.2020)
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Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses
Rodríguez-Ubreva, Javier, Arutyunyan, Anna, Bonder, Marc Jan, Del Pino-Molina, Lucía, Clark, Stephen J., de la Calle-Fabregat, Carlos, Garcia-Alonso, Luz, Handfield, Louis-François, Ciudad, Laura, Andrés-León, Eduardo, Krueger, Felix, Català-Moll, Francesc, Rodríguez-Cortez, Virginia C., Polanski, Krzysztof, Mamanova, Lira, van Dongen, Stijn, Kiselev, Vladimir Yu, Martínez-Saavedra, María T., Heyn, Holger, Martín, Javier, Warnatz, Klaus, López-Granados, Eduardo, Rodríguez-Gallego, Carlos, Stegle, Oliver, Kelsey, Gavin, Vento-Tormo, Roser, Ballestar, Esteban
Published in Nature communications (01.04.2022)
Published in Nature communications (01.04.2022)
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Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease
Garcia-Gomez, Antonio, Li, Tianlu, de la Calle-Fabregat, Carlos, Rodríguez-Ubreva, Javier, Ciudad, Laura, Català-Moll, Francesc, Godoy-Tena, Gerard, Martín-Sánchez, Montserrat, San-Segundo, Laura, Muntión, Sandra, Morales, Xabier, Ortiz-de-Solórzano, Carlos, Oyarzabal, Julen, San José-Enériz, Edurne, Esteller, Manel, Agirre, Xabier, Prosper, Felipe, Garayoa, Mercedes, Ballestar, Esteban
Published in Nature communications (18.01.2021)
Published in Nature communications (18.01.2021)
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Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection
Barmada, Anis, Handfield, Louis‐François, Godoy‐Tena, Gerard, Calle‐Fabregat, Carlos, Ciudad, Laura, Arutyunyan, Anna, Andrés‐León, Eduardo, Hoo, Regina, Porter, Tarryn, Oszlanczi, Agnes, Richardson, Laura, Calero‐Nieto, Fernando J., Wilson, Nicola K., Marchese, Domenica, Sancho‐Serra, Carmen, Carrillo, Jorge, Presas‐Rodríguez, Silvia, Ramo‐Tello, Cristina, Ruiz‐Sanmartin, Adolfo, Ferrer, Ricard, Ruiz‐Rodriguez, Juan Carlos, Martínez‐Gallo, Mónica, Munera‐Campos, Mónica, Carrascosa, Jose Manuel, Göttgens, Berthold, Heyn, Holger, Prigmore, Elena, Casafont‐Solé, Ivette, Solanich, Xavier, Sánchez‐Cerrillo, Ildefonso, González‐Álvaro, Isidoro, Raimondo, Maria Gabriella, Ramming, Andreas, Martin, Javier, Martínez‐Cáceres, Eva, Ballestar, Esteban, Vento‐Tormo1, Roser, Rodríguez‐Ubreva, Javier
Published in European journal of immunology (01.01.2024)
Published in European journal of immunology (01.01.2024)
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C/EBPa-Mediated Activation of MicroRNAs 34a and 223 Inhibits Lef1 Expression To Achieve Efficient Reprogramming into Macrophages
Javier Rodriguez-Ubreva, Laura Ciudad, Chris van Oevelen, Maribel Parra, Thomas Graf, Esteban Ballestar
Published in Molecular and Cellular Biology (01.03.2014)
Published in Molecular and Cellular Biology (01.03.2014)
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Tinostamustine (EDO-S101), an Alkylating Deacetylase Inhibitor, Enhances the Efficacy of Daratumumab in Multiple Myeloma by Upregulation of CD38 and NKG2D Ligands
Díaz-Tejedor, Andrea, Rodríguez-Ubreva, Javier, Ciudad, Laura, Lorenzo-Mohamed, Mauro, González-Rodríguez, Marta, Castellanos, Bárbara, Sotolongo-Ravelo, Janet, San-Segundo, Laura, Corchete, Luis A, González-Méndez, Lorena, Martín-Sánchez, Montserrat, Mateos, María-Victoria, Ocio, Enrique M, Garayoa, Mercedes, Paíno, Teresa
Published in International journal of molecular sciences (01.05.2024)
Published in International journal of molecular sciences (01.05.2024)
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Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of inflammatory cytokines
Godoy-Tena, Gerard, Barmada, Anis, Morante-Palacios, Octavio, de la Calle-Fabregat, Carlos, Martins-Ferreira, Ricardo, Ferreté-Bonastre, Anna G, Ciudad, Laura, Ruiz-Sanmartín, Adolfo, Martínez-Gallo, Mónica, Ferrer, Ricard, Ruiz-Rodriguez, Juan Carlos, Rodríguez-Ubreva, Javier, Vento-Tormo, Roser, Ballestar, Esteban
Published in Genome medicine (29.11.2022)
Published in Genome medicine (29.11.2022)
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Impaired CpG Demethylation in Common Variable Immunodeficiency Associates With B Cell Phenotype and Proliferation Rate
Del Pino-Molina, Lucía, Rodríguez-Ubreva, Javier, Torres Canizales, Juan, Coronel-Díaz, María, Kulis, Marta, Martín-Subero, José I, van der Burg, Mirjam, Ballestar, Esteban, López-Granados, Eduardo
Published in Frontiers in immunology (24.04.2019)
Published in Frontiers in immunology (24.04.2019)
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B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion
Hernando, Henar, Shannon-Lowe, Claire, Islam, Abul B, Al-Shahrour, Fatima, Rodríguez-Ubreva, Javier, Rodríguez-Cortez, Virginia C, Javierre, Biola M, Mangas, Cristina, Fernández, Agustín F, Parra, Maribel, Delecluse, Henri-Jacques, Esteller, Manel, López-Granados, Eduardo, Fraga, Mario F, López-Bigas, Nuria, Ballestar, Esteban
Published in Genome biology (15.01.2013)
Published in Genome biology (15.01.2013)
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SHP-1 in cell-cycle regulation
López-Ruiz, Pilar, Rodriguez-Ubreva, Javier, Cariaga, Ariel Ernesto, Cortes, María Alicia, Colás, Begoña
Published in Anti-cancer agents in medicinal chemistry (01.01.2011)
Published in Anti-cancer agents in medicinal chemistry (01.01.2011)
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PU.1 target genes undergo Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiation
de la Rica, Lorenzo, Rodríguez-Ubreva, Javier, García, Mireia, Islam, Abul BMMK, Urquiza, José M, Hernando, Henar, Christensen, Jesper, Helin, Kristian, Gómez-Vaquero, Carmen, Ballestar, Esteban
Published in Genome biology (01.01.2013)
Published in Genome biology (01.01.2013)
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Epstein-Barr virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation
Hernando, Henar, Islam, Abul B M M K, Rodríguez-Ubreva, Javier, Forné, Ignasi, Ciudad, Laura, Imhof, Axel, Shannon-Lowe, Claire, Ballestar, Esteban
Published in Nucleic acids research (01.01.2014)
Published in Nucleic acids research (01.01.2014)
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Gains of DNA methylation in myeloid terminal differentiation are dispensable for gene silencing but influence the differentiated phenotype
Vento‐Tormo, Roser, Álvarez‐Errico, Damiana, Rodríguez‐Ubreva, Javier, Ballestar, Esteban
Published in The FEBS journal (01.05.2015)
Published in The FEBS journal (01.05.2015)
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Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites
Rodríguez-Cortez, Virginia C., Martínez-Redondo, Paloma, Català-Moll, Francesc, Rodríguez-Ubreva, Javier, Garcia-Gomez, Antonio, Poorani-Subramani, Ganesh, Ciudad, Laura, Hernando, Henar, Pérez-García, Arantxa, Company, Carlos, Urquiza, José M., Ramiro, Almudena R., Di Noia, Javier M., Vaquero, Alejandro, Ballestar, Esteban
Published in Scientific reports (08.08.2017)
Published in Scientific reports (08.08.2017)
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The synovial and blood monocyte DNA methylomes mirror prognosis, evolution, and treatment in early arthritis
de la Calle-Fabregat, Carlos, Rodríguez-Ubreva, Javier, Ciudad, Laura, Ramírez, Julio, Celis, Raquel, Azuaga, Ana Belén, Cuervo, Andrea, Graell, Eduard, Pérez-García, Carolina, Díaz-Torné, César, Salvador, Georgina, Gómez-Puerta, José A, Haro, Isabel, Sanmartí, Raimon, Cañete, Juan D, Ballestar, Esteban
Published in JCI insight (09.05.2022)
Published in JCI insight (09.05.2022)
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P718: EPIGENOME PROFILING REVEALS ABERRANT DNA METHYLATION SIGNATURE IN GATA2 DEFICIENCY
Marin‐Bejar, Oskar, Romero‐Moya, Damia, Rodriguez‐Ubreva, Javier, Distefano, Maximiliano, Lessi, Francesca, Aretini, Paolo, Liquori, Alessandro, Castaño, Julio, Kozyra, Emilia, Kotmayer, Lili, Bueno, Clara, Cervera, José, Carlos Rodriguez‐Gallego, José, F Nomdedeu, Josep, Murillo‐Sanjuán, Laura, Díaz de Heredia, Cristina, Pérez‐Martinez, Antonio, López‐Cardenas, Félix, Martínez‐Laperche, Carolina, Dorado‐Herrero, Nieves, M Marco, Francisco, Prósper, Felipe, Menendez, Pablo, Valcárcel, David, Ballestar, Esteban, Bödör, Csaba, Bigas, Anna, Catalá, Albert, W Wlodarski, Marcin, Giorgetti, Alessandra
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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