2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer
Blomme, Arnaud, Ford, Catriona A., Mui, Ernest, Patel, Rachana, Ntala, Chara, Jamieson, Lauren E., Planque, Mélanie, McGregor, Grace H., Peixoto, Paul, Hervouet, Eric, Nixon, Colin, Salji, Mark, Gaughan, Luke, Markert, Elke, Repiscak, Peter, Sumpton, David, Blanco, Giovanny Rodriguez, Lilla, Sergio, Kamphorst, Jurre J., Graham, Duncan, Faulds, Karen, MacKay, Gillian M., Fendt, Sarah-Maria, Zanivan, Sara, Leung, Hing Y.
Published in Nature communications (19.05.2020)
Published in Nature communications (19.05.2020)
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Disruption of the TCA cycle reveals an ATF4-dependent integration of redox and amino acid metabolism
Ryan, Dylan Gerard, Yang, Ming, Prag, Hiran A, Blanco, Giovanny Rodriguez, Nikitopoulou, Efterpi, Segarra-Mondejar, Marc, Powell, Christopher A, Young, Tim, Burger, Nils, Miljkovic, Jan Lj, Minczuk, Michal, Murphy, Michael P, von Kriegsheim, Alex, Frezza, Christian
Published in eLife (23.12.2021)
Published in eLife (23.12.2021)
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Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function
Santi, Alice, Kay, Emily J, Neilson, Lisa J, McGarry, Lynn, Lilla, Sergio, Mullin, Margaret, Paul, Nikki R, Fercoq, Frédéric, Koulouras, Grigorios, Rodriguez Blanco, Giovanny, Athineos, Dimitris, Mason, Susan, Hughes, Mark, Thomson, Gemma, Kieffer, Yann, Nixon, Colin, Blyth, Karen, Mechta-Grigoriou, Fatima, Carlin, Leo M, Zanivan, Sara
Published in Science signaling (12.03.2024)
Published in Science signaling (12.03.2024)
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SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer
Martinez, Rafael S, Salji, Mark J, Rushworth, Linda, Ntala, Chara, Rodriguez Blanco, Giovanny, Hedley, Ann, Clark, William, Peixoto, Paul, Hervouet, Eric, Renaude, Elodie, Kung, Sonia H Y, Galbraith, Laura C A, Nixon, Colin, Lilla, Sergio, MacKay, Gillian M, Fazli, Ladan, Gaughan, Luke, Sumpton, David, Gleave, Martin E, Zanivan, Sara, Blomme, Arnaud, Leung, Hing Y
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Bidirectional Cross-Talk between Biliary Epithelium and Th17 Cells Promotes Local Th17 Expansion and Bile Duct Proliferation in Biliary Liver Diseases
Jeffery, Hannah C, Hunter, Stuart, Humphreys, Elizabeth H, Bhogal, Ricky, Wawman, Rebecca E, Birtwistle, Jane, Atif, Muhammad, Bagnal, Christopher J, Rodriguez Blanco, Giovanny, Richardson, Naomi, Warner, Suz, Dunn, Warwick B, Afford, Simon C, Adams, David H, Oo, Ye Htun
Published in The Journal of immunology (1950) (01.09.2019)
Published in The Journal of immunology (1950) (01.09.2019)
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THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer
Blomme, Arnaud, Peter, Coralie, Mui, Ernest, Rodriguez Blanco, Giovanny, An, Ning, Mason, Louise M, Jamieson, Lauren E, McGregor, Grace H, Lilla, Sergio, Ntala, Chara, Patel, Rachana, Thiry, Marc, Kung, Sonia H Y, Leclercq, Marine, Ford, Catriona A, Rushworth, Linda K, McGarry, David J, Mason, Susan, Repiscak, Peter, Nixon, Colin, Salji, Mark J, Markert, Elke, MacKay, Gillian M, Kamphorst, Jurre J, Graham, Duncan, Faulds, Karen, Fazli, Ladan, Gleave, Martin E, Avezov, Edward, Edwards, Joanne, Yin, Huabing, Sumpton, David, Blyth, Karen, Close, Pierre, Murphy, Daniel J, Zanivan, Sara, Leung, Hing Y
Published in EMBO molecular medicine (07.03.2022)
Published in EMBO molecular medicine (07.03.2022)
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Differential tissue expression of extracellular vesicle‐derived proteins in prostate cancer
Duijvesz, Diederick, Rodriguez‐Blanco, Giovanny, Hoogland, A. Marije, Verhoef, Esther I., Dekker, Lennard J., Roobol, Monique J., Leenders, Geert J. L. H., Luider, Theo M., Jenster, Guido
Published in The Prostate (01.06.2019)
Published in The Prostate (01.06.2019)
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Targeting the Metabolic Response to Statin-Mediated Oxidative Stress Produces a Synergistic Antitumor Response
McGregor, Grace H, Campbell, Andrew D, Fey, Sigrid K, Tumanov, Sergey, Sumpton, David, Blanco, Giovanny Rodriguez, Mackay, Gillian, Nixon, Colin, Vazquez, Alexei, Sansom, Owen J, Kamphorst, Jurre J
Published in Cancer research (Chicago, Ill.) (15.01.2020)
Published in Cancer research (Chicago, Ill.) (15.01.2020)
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NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease
Ryan, Eilise M, Sadiku, Pranvera, Coelho, Patricia, Watts, Emily R, Zhang, Ailiang, Howden, Andrew J M, Sanchez-Garcia, Manuel A, Bewley, Martin, Cole, Joby, McHugh, Brian J, Vermaelen, Wesley, Ghesquiere, Bart, Carmeliet, Peter, Rodriguez Blanco, Giovanny, Von Kriegsheim, Alex, Sanchez, Yolanda, Rumsey, William, Callahan, James F, Cooper, George, Parkinson, Nicholas, Baillie, Kenneth, Cantrell, Doreen A, McCafferty, John, Choudhury, Gourab, Singh, Dave, Dockrell, David H, Whyte, Moira K B, Walmsley, Sarah R
Published in American journal of respiratory and critical care medicine (15.04.2023)
Published in American journal of respiratory and critical care medicine (15.04.2023)
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Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer
Almanza, Aitor, Mnich, Katarzyna, Blomme, Arnaud, Robinson, Claire M., Rodriguez-Blanco, Giovanny, Kierszniowska, Sylwia, McGrath, Eoghan P., Le Gallo, Matthieu, Pilalis, Eleftherios, Swinnen, Johannes V., Chatziioannou, Aristotelis, Chevet, Eric, Gorman, Adrienne M., Samali, Afshin
Published in Nature communications (06.05.2022)
Published in Nature communications (06.05.2022)
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Collection of Untargeted Metabolomic Data for Mammalian Urine Applying HILIC and Reversed Phase Ultra Performance Liquid Chromatography Methods Coupled to a Q Exactive Mass Spectrometer
Najdekr, Lukáš, Blanco, Giovanny Rodriguez, Dunn, Warwick B
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2019)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2019)
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Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition
Roca-Portoles, Alba, Rodriguez-Blanco, Giovanny, Sumpton, David, Cloix, Catherine, Mullin, Margaret, Mackay, Gillian M., O’Neill, Katelyn, Lemgruber, Leandro, Luo, Xu, Tait, Stephen W. G.
Published in Cell death & disease (13.08.2020)
Published in Cell death & disease (13.08.2020)
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Formate induces a metabolic switch in nucleotide and energy metabolism
Oizel, Kristell, Tait-Mulder, Jacqueline, Fernandez-de-Cossio-Diaz, Jorge, Pietzke, Matthias, Brunton, Holly, Lilla, Sergio, Dhayade, Sandeep, Athineos, Dimitri, Blanco, Giovanny Rodriguez, Sumpton, David, Mackay, Gillian M., Blyth, Karen, Zanivan, Sara R., Meiser, Johannes, Vazquez, Alexei
Published in Cell death & disease (04.05.2020)
Published in Cell death & disease (04.05.2020)
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Pilot RNAi screening using mammalian cell-based system identifies novel putative silencing factors including Kat5/Tip60
Venkateswaran Venkatasubramani, Anuroop, McLaughlin, Katy, Rodriguez Blanco, Giovanny, Larionov, Vladimir, Kagansky, Alexander
Published in AIMS biophysics (01.01.2015)
Published in AIMS biophysics (01.01.2015)
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Gender-Specific Bile Acid Profiles in Non-Alcoholic Fatty Liver Disease
Fitzinger, Julia, Rodriguez-Blanco, Giovanny, Herrmann, Markus, Borenich, Andrea, Stauber, Rudolf, Aigner, Elmar, Mangge, Harald
Published in Nutrients (01.01.2024)
Published in Nutrients (01.01.2024)
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MYC sensitises cells to apoptosis by driving energetic demand
Edwards-Hicks, Joy, Su, Huizhong, Mangolini, Maurizio, Yoneten, Kubra K., Wills, Jimi, Rodriguez-Blanco, Giovanny, Young, Christine, Cho, Kevin, Barker, Heather, Muir, Morwenna, Guerrieri, Ania Naila, Li, Xue-Feng, White, Rachel, Manasterski, Piotr, Mandrou, Elena, Wills, Karen, Chen, Jingyu, Abraham, Emily, Sateri, Kianoosh, Qian, Bin-Zhi, Bankhead, Peter, Arends, Mark, Gammoh, Noor, von Kriegsheim, Alex, Patti, Gary J., Sims, Andrew H., Acosta, Juan Carlos, Brunton, Valerie, Kranc, Kamil R., Christophorou, Maria, Pearce, Erika L., Ringshausen, Ingo, Finch, Andrew J.
Published in Nature communications (09.08.2022)
Published in Nature communications (09.08.2022)
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Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells
Lyall, Marcus J., Cartier, Jessy, Thomson, John P., Cameron, Kate, Meseguer-Ripolles, Jose, O'Duibhir, Eoghan, Szkolnicka, Dagmara, Villarin, Baltasar Lucendo, Wang, Yu, Blanco, Giovanny Rodriguez, Dunn, Warwick B., Meehan, Richard R., Hay, David C., Drake, Amanda J.
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05.07.2018)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05.07.2018)
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msPurity: Automated Evaluation of Precursor Ion Purity for Mass Spectrometry-Based Fragmentation in Metabolomics
Lawson, Thomas N, Weber, Ralf J. M, Jones, Martin R, Chetwynd, Andrew J, Rodrı́guez-Blanco, Giovanny, Di Guida, Riccardo, Viant, Mark R, Dunn, Warwick B
Published in Analytical chemistry (Washington) (21.02.2017)
Published in Analytical chemistry (Washington) (21.02.2017)
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Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturation
Dembitz, Vilma, Lawson, Hannah, Burt, Richard, Natani, Sirisha, Philippe, Céline, James, Sophie C., Atkinson, Samantha, Durko, Jozef, Wang, Lydia M., Campos, Joana, Magee, Aoife M. S., Woodley, Keith, Austin, Michael J., Rio-Machin, Ana, Casado, Pedro, Bewicke-Copley, Findlay, Rodriguez Blanco, Giovanny, Pereira-Martins, Diego, Oudejans, Lieve, Boet, Emeline, von Kriegsheim, Alex, Schwaller, Juerg, Finch, Andrew J., Patel, Bela, Sarry, Jean-Emmanuel, Tamburini, Jerome, Schuringa, Jan Jacob, Hazlehurst, Lori, Copland III, John A., Yuneva, Mariia, Peck, Barrie, Cutillas, Pedro, Fitzgibbon, Jude, Rouault-Pierre, Kevin, Kranc, Kamil, Gallipoli, Paolo
Published in Leukemia (26.08.2024)
Published in Leukemia (26.08.2024)
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Impact of High-Fat Diet and Exercise on Bone and Bile Acid Metabolism in Rats
Alonso, Nerea, Almer, Gunter, Semeraro, Maria Donatella, Rodriguez-Blanco, Giovanny, Fauler, Günter, Anders, Ines, Ritter, Gerald, Vom Scheidt, Annika, Hammer, Niels, Gruber, Hans-Jürgen, Herrmann, Markus
Published in Nutrients (01.06.2024)
Published in Nutrients (01.06.2024)
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