Human Protein Tyrosine Phosphatase 1B (PTP1B): From Structure to Clinical Inhibitor Perspectives
Liu, Rongxing, Mathieu, Cécile, Berthelet, Jérémy, Zhang, Wenchao, Dupret, Jean-Marie, Rodrigues Lima, Fernando
Published in International journal of molecular sciences (24.06.2022)
Published in International journal of molecular sciences (24.06.2022)
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Targeting neutrophil extracellular traps: A novel strategy in hematologic malignancies
Liu, Rongxing, Zhang, Jin, Rodrigues Lima, Fernando, Zeng, Jinhao, Nian, Qing
Published in Biomedicine & pharmacotherapy (01.04.2024)
Published in Biomedicine & pharmacotherapy (01.04.2024)
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Journal Article
Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy
Nian, Qing, Berthelet, Jérémy, Parlato, Marianna, Mechaly, Ariel E., Liu, Rongxing, Dupret, Jean‐Marie, Cerf‐Bensussan, Nadine, Haouz, Ahmed, Rodrigues Lima, Fernando
Published in Protein science (01.02.2022)
Published in Protein science (01.02.2022)
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UNC45A deficiency causes microvillus inclusion disease-like phenotype by impairing myosin VB-dependent apical trafficking
Duclaux-Loras, Rémi, Lebreton, Corinne, Berthelet, Jérémy, Charbit-Henrion, Fabienne, Nicolle, Ophelie, Revenu des Courtils, Céline, Waich, Stephanie, Valovka, Taras, Khiat, Anis, Rabant, Marion, Racine, Caroline, Guerrera, Ida Chiara, Baptista, Júlia, Mahe, Maxime M, Hess, Michael W, Durel, Béatrice, Lefort, Nathalie, Banal, Céline, Parisot, Mélanie, Talbotec, Cecile, Lacaille, Florence, Ecochard-Dugelay, Emmanuelle, Demir, Arzu Meltem, Vogel, Georg F, Faivre, Laurence, Rodrigues, Astor, Fowler, Darren, Janecke, Andreas R, Müller, Thomas, Huber, Lukas A, Rodrigues-Lima, Fernando, Ruemmele, Frank M, Uhlig, Holm H, Del Bene, Filippo, Michaux, Grégoire, Cerf-Bensussan, Nadine, Parlato, Marianna
Published in The Journal of clinical investigation (16.05.2022)
Published in The Journal of clinical investigation (16.05.2022)
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Journal Article
Biochemical, Enzymatic, and Computational Characterization of Recurrent Somatic Mutations of the Human Protein Tyrosine Phosphatase PTP1B in Primary Mediastinal B Cell Lymphoma
Liu, Rongxing, Sun, Yujie, Berthelet, Jérémy, Bui, Linh-Chi, Xu, Ximing, Viguier, Mireille, Dupret, Jean-Marie, Deshayes, Frédérique, Rodrigues Lima, Fernando
Published in International journal of molecular sciences (24.06.2022)
Published in International journal of molecular sciences (24.06.2022)
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Journal Article
Cisplatin causes covalent inhibition of protein-tyrosine phosphatase 1B (PTP1B) through reaction with its active site cysteine: Molecular, cellular and in vivo mice studies
Liu, Rongxing, Zhang, Wenchao, Gou, Panhong, Berthelet, Jérémy, Nian, Qing, Chevreux, Guillaume, Legros, Véronique, Moroy, Gautier, Bui, Linh-Chi, Wang, Li, Dupret, Jean-Marie, Deshayes, Frédérique, Rodrigues Lima, Fernando
Published in Biomedicine & pharmacotherapy (01.09.2022)
Published in Biomedicine & pharmacotherapy (01.09.2022)
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Journal Article
Systemic inflammatory syndrome in children with FARSA deficiency
Charbit‐Henrion, Fabienne, Goguyer‐Deschaumes, Roman, Borensztajn, Keren, Mirande, Marc, Berthelet, Jérémy, Rodrigues‐Lima, Fernando, Khiat, Anis, Frémond, Marie‐Louise, Bader‐Meunier, Brigitte, Rodari, Marco M., Seabra, Luis, Rice, Gillian I., Legendre, Marie, Drummond, David, Berteloot, Laureline, Roux, Charles‐Joris, Boddaert, Nathalie, Drabent, Philippe, Molina, Thierry Jo, Lacaille, Florence, Kossorotoff, Manoelle, Cerf‐Bensussan, Nadine, Parlato, Marianna, Hadchouel, Alice
Published in Clinical genetics (01.05.2022)
Published in Clinical genetics (01.05.2022)
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Journal Article
Structural and enzymatic evidence for the methylation of the ACK1 tyrosine kinase by the histone lysine methyltransferase SETD2
Le Coadou, Louise, Berthelet, Jérémy, Mechaly, Ariel E, Michail, Christina, Bui, Linh-Chi, Dairou, Julien, Haouz, Ahmed, Dupret, Jean-Marie, Rodrigues Lima, Fernando
Published in Biochemical and biophysical research communications (05.02.2024)
Published in Biochemical and biophysical research communications (05.02.2024)
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Journal Article
U2AF1 in various neoplastic diseases and relevant targeted therapies for malignant cancers with complex mutations (Review)
Nian, Qing, Li, Yihui, Li, Jingwei, Zhao, Liyun, Lima, Fernando Rodrigues, Zeng, Jinhao, Liu, Rongxing, Ye, Zhijun
Published in Oncology reports (01.01.2024)
Published in Oncology reports (01.01.2024)
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Journal Article
Haploinsufficiency in PTPN2 leads to early-onset systemic autoimmunity from Evans syndrome to lupus
Jeanpierre, Marie, Cognard, Jade, Tusseau, Maud, Riller, Quentin, Bui, Linh-Chi, Berthelet, Jérémy, Laurent, Audrey, Crickx, Etienne, Parlato, Marianna, Stolzenberg, Marie-Claude, Suarez, Felipe, Leverger, Guy, Aladjidi, Nathalie, Collardeau-Frachon, Sophie, Pietrement, Christine, Malphettes, Marion, Froissart, Antoine, Bole-Feysot, Christine, Cagnard, Nicolas, Rodrigues Lima, Fernando, Walzer, Thierry, Rieux-Laucat, Frédéric, Belot, Alexandre, Mathieu, Anne-Laure
Published in The Journal of experimental medicine (02.09.2024)
Published in The Journal of experimental medicine (02.09.2024)
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Legionella para-effectors target chromatin and promote bacterial replication
Schator, Daniel, Mondino, Sonia, Berthelet, Jérémy, Di Silvestre, Cristina, Ben Assaya, Mathilde, Rusniok, Christophe, Rodrigues-Lima, Fernando, Wehenkel, Annemarie, Buchrieser, Carmen, Rolando, Monica
Published in Nature communications (14.04.2023)
Published in Nature communications (14.04.2023)
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Journal Article
Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues
Zhang, Wenchao, Berthelet, Jérémy, Michail, Christina, Bui, Linh-Chi, Gou, Panhong, Liu, Rongxing, Duval, Romain, Renault, Justine, Dupret, Jean-Marie, Guidez, Fabien, Chomienne, Christine, Rodrigues Lima, Fernando
Published in Free radical biology & medicine (01.01.2021)
Published in Free radical biology & medicine (01.01.2021)
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Variable pathogenic potentials of mutations located in the desmin alpha-helical domain
Goudeau, Bertrand, Rodrigues-Lima, Fernando, Fischer, Dirk, Casteras-Simon, Monique, Sambuughin, Nyamkhishig, de Visser, Marianne, Laforet, Pascal, Ferrer, Xavier, Chapon, Françoise, Sjöberg, Gunnar, Kostareva, Anna, Sejersen, Thomas, Dalakas, Marinos C., Goldfarb, Lev G., Vicart, Patrick
Published in Human mutation (01.09.2006)
Published in Human mutation (01.09.2006)
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Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylation
Boy, Maxime, Bisio, Valeria, Zhao, Lin-Pierre, Guidez, Fabien, Schell, Bérénice, Lereclus, Emilie, Henry, Guylaine, Villemonteix, Juliette, Rodrigues-Lima, Fernando, Gagne, Katia, Retiere, Christelle, Larcher, Lise, Kim, Rathana, Clappier, Emmanuelle, Sebert, Marie, Mekinian, Arsène, Fain, Olivier, Caignard, Anne, Espeli, Marion, Balabanian, Karl, Toubert, Antoine, Fenaux, Pierre, Ades, Lionel, Dulphy, Nicolas
Published in Nature communications (03.02.2023)
Published in Nature communications (03.02.2023)
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Journal Article
Dynamic methylation of histone H3K18 in differentiating Theileria parasites
Cheeseman, Kevin, Jannot, Guillaume, Lourenço, Nelly, Villares, Marie, Berthelet, Jérémy, Calegari-Silva, Teresa, Hamroune, Juliette, Letourneur, Franck, Rodrigues-Lima, Fernando, Weitzman, Jonathan B.
Published in Nature communications (28.05.2021)
Published in Nature communications (28.05.2021)
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Journal Article
DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives
Neumann, Fernanda, Gourdain, Stéphanie, Albac, Christelle, Dekker, Alain D, Bui, Linh Chi, Dairou, Julien, Schmitz-Afonso, Isabelle, Hue, Nathalie, Rodrigues-Lima, Fernando, Delabar, Jean M, Potier, Marie-Claude, Le Caër, Jean-Pierre, Touboul, David, Delatour, Benoît, Cariou, Kevin, Dodd, Robert H
Published in Scientific reports (12.02.2018)
Published in Scientific reports (12.02.2018)
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SPARC in hematologic malignancies and novel technique for hematological disease with its abnormal expression
Nian, Qing, Li, Jingwei, Han, ZhongYu, Liang, Qi, Liu, Maoyu, Yang, Chan, Rodrigues-Lima, Fernando, Jiang, Tao, Zhao, Liyun, Zeng, Jinhao, Liu, Chi, Shi, Jianyou
Published in Biomedicine & pharmacotherapy (01.09.2022)
Published in Biomedicine & pharmacotherapy (01.09.2022)
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Journal Article
T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide
Nian, Qing, Berthelet, Jérémy, Zhang, Wenchao, Bui, Linh-Chi, Liu, Rongxing, Xu, Ximing, Duval, Romain, Ganesan, Saravanan, Leger, Thibaut, Chomienne, Christine, Busi, Florent, Guidez, Fabien, Dupret, Jean-Marie, Rodrigues Lima, Fernando
Published in Molecular pharmacology (01.08.2019)
Published in Molecular pharmacology (01.08.2019)
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